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The map label for this gene is oppA [H]

Identifier: 110632400

GI number: 110632400

Start: 45967

End: 47568

Strand: Reverse

Name: oppA [H]

Synonym: Meso_0038

Alternate gene names: 110632400

Gene position: 47568-45967 (Counterclockwise)

Preceding gene: 110632401

Following gene: 110632399

Centisome position: 1.08

GC content: 59.05

Gene sequence:

>1602_bases
ATGCTGAAAAGTGCGGGAATCCGGCCCCTGATGGCCGGCGCTCTGGTGATGGCCGGAGTGTTTTTCGGTGCAAGCACGGC
GCTTGCCCAGGTCACCTATATCCGCGGCAATGACGCGAACCCCGAAACTTTGGACCAGCACAAGACTTCGACAATCGCCG
AGGCGAACATCCTGCGCGACCTCTATGAGGGGCTGGTGATCTACAGCGCGAAGGCGGAGGTCATCCCCGGTGTCGCAGAA
AGCTGGGAAACGTCCGATGACGGCCTAGTCTGGACATTCAAGCTGCGCGACGCGAATTGGTCGAACGGTGATCCGGTGAC
GGCGGAGGATTTCGTCTTCTCCTACCAGCGGATATTGAATCCGGAGACCGGCGCGAAATACGCCAACATGCTCTACGTCA
TCAAGAACGGCGAGAAAGTGAACAAGGGCGAGCTTGAGCCCGGCGAGCTAGGCGTGCGCGCAGTTGACGACAAGACGCTG
GAGATCACGCTAGAGAACCCGACACCTTATTTCCTCCAGCTCCTCACCCACCAGACGAGCTATCCGGTGCACAAGGCGAG
TGTCGAGGAACACGGCTCCGATTTCGTGAAGCCGGAGAATATGGTCACCAATGGACCCTACAAGCTCGTCTCCTTCGTAC
CCAACGACAAGGTGGTGCTGGAGAAAAATCCCGAGTTTCGCGAGGCGGACAAGGTTTCGATCGACCGCGTGGAATTCGTG
CCCTTCGAGGAGCGTGCGACCTGCGTGCGCCGCTTCGAGGCGGGCGAGGTGCTGAGTTGCTCCGACCTGCCGGCAGAGCA
GCTCCAGTCGCTCAAGGAACGGTTGGGCGAACAAGTGCATGTGGTGCCCTATCTCGGAACTTATTATTACGCGCTCAACA
ACAAGAGGGACGATCTGAAGGACCCGCGAGTCCGCCAGGCGCTTTCCATGATGGTCGACCGCGAGTTCATCGCCAACGAA
ATCTGGTCGGGCGCCATGCTGCCTGCCTACACCTTCGTGCCGCCTGGCATCGGCAATTACGAGGGTGGCGGGCCGAAGGT
GGAATGGGCCGATCTTGACCCGCTCGACAAGGAAGACCAGGCGATCGCCCTCATGAAGGAGGCCGGCTACAGCCCCGATA
ATCCGCTGGAGCTGGAGATCTCGTATAGCGCGGGCGAAAACCACAAGAACACGGCGACGGCCATCGCCGACATGTGGAAA
CCGCTGGGCGTTAATGTGACCTTCAACGTCCGCGACGGCTCGGCGCATTATTCGCATCTGCGCGACAGCGACGATTATGA
GGTGGCGCGCGCCGGCTGGATTGGCGACTTTTCAGACCCGGTAAATTTCCTTCAGCTCTGGGAAAGCGACAATACGGGCT
TCAACTATTCCAAATACGAGAACCCCGAATACGACAAGCTGATGGACCAGGCGGCCGCCGAAAGCGACCTTGCAAAACGC
GAGGAGATCCTGCGCCAGGCGGAAGCCCTTCTCGTGGAGGATGCCGCCGTTATCTCGATGCTCTATTATTCGTCCATGTC
GCTCGTCTCGCCCAAGCTGAAGGGCTGGGAAGACAATATTCAGAACGCTCACGCCACGCGCTGGATGAGCATTTCCGAAT
AG

Upstream 100 bases:

>100_bases
GGCGGTCAGACATAGCTGACGGAGGGAACGGTACCAAGCAGCCACAGGTGCGTTTAAGCAACAACAAAAACATGAACGCG
AAAGATGATGGGAGCTTATC

Downstream 100 bases:

>100_bases
TTCCTGCGTCCGCGGGGCCGCGCAGAAAAGCGCGCGGCTCCGGGACCCGACGAGAGCAACGGCGATGCTTGCCTATGTTT
TGCGGCGCCTATTCGGCGCG

Product: extracellular solute-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MLKSAGIRPLMAGALVMAGVFFGASTALAQVTYIRGNDANPETLDQHKTSTIAEANILRDLYEGLVIYSAKAEVIPGVAE
SWETSDDGLVWTFKLRDANWSNGDPVTAEDFVFSYQRILNPETGAKYANMLYVIKNGEKVNKGELEPGELGVRAVDDKTL
EITLENPTPYFLQLLTHQTSYPVHKASVEEHGSDFVKPENMVTNGPYKLVSFVPNDKVVLEKNPEFREADKVSIDRVEFV
PFEERATCVRRFEAGEVLSCSDLPAEQLQSLKERLGEQVHVVPYLGTYYYALNNKRDDLKDPRVRQALSMMVDREFIANE
IWSGAMLPAYTFVPPGIGNYEGGGPKVEWADLDPLDKEDQAIALMKEAGYSPDNPLELEISYSAGENHKNTATAIADMWK
PLGVNVTFNVRDGSAHYSHLRDSDDYEVARAGWIGDFSDPVNFLQLWESDNTGFNYSKYENPEYDKLMDQAAAESDLAKR
EEILRQAEALLVEDAAVISMLYYSSMSLVSPKLKGWEDNIQNAHATRWMSISE

Sequences:

>Translated_533_residues
MLKSAGIRPLMAGALVMAGVFFGASTALAQVTYIRGNDANPETLDQHKTSTIAEANILRDLYEGLVIYSAKAEVIPGVAE
SWETSDDGLVWTFKLRDANWSNGDPVTAEDFVFSYQRILNPETGAKYANMLYVIKNGEKVNKGELEPGELGVRAVDDKTL
EITLENPTPYFLQLLTHQTSYPVHKASVEEHGSDFVKPENMVTNGPYKLVSFVPNDKVVLEKNPEFREADKVSIDRVEFV
PFEERATCVRRFEAGEVLSCSDLPAEQLQSLKERLGEQVHVVPYLGTYYYALNNKRDDLKDPRVRQALSMMVDREFIANE
IWSGAMLPAYTFVPPGIGNYEGGGPKVEWADLDPLDKEDQAIALMKEAGYSPDNPLELEISYSAGENHKNTATAIADMWK
PLGVNVTFNVRDGSAHYSHLRDSDDYEVARAGWIGDFSDPVNFLQLWESDNTGFNYSKYENPEYDKLMDQAAAESDLAKR
EEILRQAEALLVEDAAVISMLYYSSMSLVSPKLKGWEDNIQNAHATRWMSISE
>Mature_533_residues
MLKSAGIRPLMAGALVMAGVFFGASTALAQVTYIRGNDANPETLDQHKTSTIAEANILRDLYEGLVIYSAKAEVIPGVAE
SWETSDDGLVWTFKLRDANWSNGDPVTAEDFVFSYQRILNPETGAKYANMLYVIKNGEKVNKGELEPGELGVRAVDDKTL
EITLENPTPYFLQLLTHQTSYPVHKASVEEHGSDFVKPENMVTNGPYKLVSFVPNDKVVLEKNPEFREADKVSIDRVEFV
PFEERATCVRRFEAGEVLSCSDLPAEQLQSLKERLGEQVHVVPYLGTYYYALNNKRDDLKDPRVRQALSMMVDREFIANE
IWSGAMLPAYTFVPPGIGNYEGGGPKVEWADLDPLDKEDQAIALMKEAGYSPDNPLELEISYSAGENHKNTATAIADMWK
PLGVNVTFNVRDGSAHYSHLRDSDDYEVARAGWIGDFSDPVNFLQLWESDNTGFNYSKYENPEYDKLMDQAAAESDLAKR
EEILRQAEALLVEDAAVISMLYYSSMSLVSPKLKGWEDNIQNAHATRWMSISE

Specific function: This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=538, Percent_Identity=37.546468401487, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI87081878, Length=490, Percent_Identity=36.734693877551, Blast_Score=328, Evalue=6e-91,
Organism=Escherichia coli, GI1789397, Length=502, Percent_Identity=34.6613545816733, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1787762, Length=539, Percent_Identity=27.8293135435993, Blast_Score=169, Evalue=6e-43,
Organism=Escherichia coli, GI1789966, Length=544, Percent_Identity=25.3676470588235, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1787052, Length=526, Percent_Identity=22.8136882129278, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789887, Length=473, Percent_Identity=24.9471458773784, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1787551, Length=526, Percent_Identity=22.6235741444867, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59637; Mature: 59637

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSAGIRPLMAGALVMAGVFFGASTALAQVTYIRGNDANPETLDQHKTSTIAEANILRD
CCCCCCCCHHHHHHHHHHHHHHCCHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
LYEGLVIYSAKAEVIPGVAESWETSDDGLVWTFKLRDANWSNGDPVTAEDFVFSYQRILN
HHCCEEEEECCHHHCCCCHHCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCC
PETGAKYANMLYVIKNGEKVNKGELEPGELGVRAVDDKTLEITLENPTPYFLQLLTHQTS
CCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHHCCC
YPVHKASVEEHGSDFVKPENMVTNGPYKLVSFVPNDKVVLEKNPEFREADKVSIDRVEFV
CCCHHHHHHHCCCCCCCCCCEECCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEEC
PFEERATCVRRFEAGEVLSCSDLPAEQLQSLKERLGEQVHVVPYLGTYYYALNNKRDDLK
CCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCEEEEEEECEEEEEECCCCCCCC
DPRVRQALSMMVDREFIANEIWSGAMLPAYTFVPPGIGNYEGGGPKVEWADLDPLDKEDQ
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCEEEECCCCCCCCCCH
AIALMKEAGYSPDNPLELEISYSAGENHKNTATAIADMWKPLGVNVTFNVRDGSAHYSHL
HHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHC
RDSDDYEVARAGWIGDFSDPVNFLQLWESDNTGFNYSKYENPEYDKLMDQAAAESDLAKR
CCCCCCCHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EEILRQAEALLVEDAAVISMLYYSSMSLVSPKLKGWEDNIQNAHATRWMSISE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHEEEEECC
>Mature Secondary Structure
MLKSAGIRPLMAGALVMAGVFFGASTALAQVTYIRGNDANPETLDQHKTSTIAEANILRD
CCCCCCCCHHHHHHHHHHHHHHCCHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
LYEGLVIYSAKAEVIPGVAESWETSDDGLVWTFKLRDANWSNGDPVTAEDFVFSYQRILN
HHCCEEEEECCHHHCCCCHHCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCC
PETGAKYANMLYVIKNGEKVNKGELEPGELGVRAVDDKTLEITLENPTPYFLQLLTHQTS
CCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHHCCC
YPVHKASVEEHGSDFVKPENMVTNGPYKLVSFVPNDKVVLEKNPEFREADKVSIDRVEFV
CCCHHHHHHHCCCCCCCCCCEECCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEEC
PFEERATCVRRFEAGEVLSCSDLPAEQLQSLKERLGEQVHVVPYLGTYYYALNNKRDDLK
CCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCEEEEEEECEEEEEECCCCCCCC
DPRVRQALSMMVDREFIANEIWSGAMLPAYTFVPPGIGNYEGGGPKVEWADLDPLDKEDQ
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCEEEECCCCCCCCCCH
AIALMKEAGYSPDNPLELEISYSAGENHKNTATAIADMWKPLGVNVTFNVRDGSAHYSHL
HHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHC
RDSDDYEVARAGWIGDFSDPVNFLQLWESDNTGFNYSKYENPEYDKLMDQAAAESDLAKR
CCCCCCCHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EEILRQAEALLVEDAAVISMLYYSSMSLVSPKLKGWEDNIQNAHATRWMSISE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187863; 9097039; 9278503; 2015910; 9298646; 9600841 [H]