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The map label for this gene is lysK [H]

Identifier: 110632379

GI number: 110632379

Start: 17262

End: 18923

Strand: Direct

Name: lysK [H]

Synonym: Meso_0017

Alternate gene names: 110632379

Gene position: 17262-18923 (Clockwise)

Preceding gene: 110632377

Following gene: 110632387

Centisome position: 0.39

GC content: 59.99

Gene sequence:

>1662_bases
ATGACGATCACGCTTGGAAACGCGCTCGAACTTACCCCGGAAGTGCTGCAGGCCGCCGCGGAAAGCAAAGCCTGGCCCTT
CGAGGAGGCGCGCAAGATCGTCAAACGTTACGAGGGAAGGGGTTTTCCCGAGACGGTGCTTTTCGAGACCGGTTACGGTC
CGTCGGGCCTGCCGCACATTGGCACGTTCGGCGAGGTGGCCCGCACGTCCATGGTGCGCCACGCCTTCCGTGTGATCACC
GAGGATAAGGTTAGGACAAAGATCCTATGCTTCTCGGACGATATGGACGGTTTGAGGAAGGTGCCTGACAATGTACCGAA
CCAGGAGATGCTGCGCGCCCATCTCGGCAAGCCGCTGACACGCGTGCCGGACCCGTTTTCCAACCAGTATCCTTCTTTCG
GCGCTGCCAACAACGCGCGGCTGAGAGCCTTCCTCGACCAGTTCGGCTTCGAATATGAGTTCGCTTCTTCGACGGAATAC
TATGCCTCGGGTCGTTTCGACGCGACGCTTTTGAAAGTCTTGGAGCGCTTCGATGAGGTAATGGCGGTCATGCTGCCTTC
GCTGCGCGAAGAGCGGGCACAGACCTATTCCCCCTTCCTGCCTATTCACCCGAAAACCGGGGTTGTGATGCAGGTGCCCA
TTGAGGAGCGAAAGCTCGACGCAGGCACGATCGTTTGGCGCGATCCTGAAAGCGGTGAGCGCTTCGAGACGCTGGTGACC
GGCGGCCATTCCAAGCTGCAGTGGAAGCCCGATTGGGCGATGCGCTGGGCGGCGCTCGGTGTCGACTATGAAATGTCCGG
CAAGGACCTGATCGACAGCGTGAAACTCGCGGCGCAGATTTGCACCGTACTCGACGGTACGCCGCCGGAAGGCTTCAACT
ATGAGCTTTTCCTGGACGAGAAGGGCCAGAAGATCTCGAAGTCCAAGGGCAACGGGCTGACCATCGATGAGTGGCTCGCC
TACGCGCCGACGGAGAGCTTGTCGCTTTATATGTTCCAGAAGCCGAAGACAGCGAAAAAGCTTTATTTCGATGTCATTCC
GAAGGCGGTGGACGACTACTATTCGTTCCTCTCGGCCTATTCCCGCCAGGACTGGCAGAACCGGCTGGGCAATCCGGTCT
GGCATATTCACGACGGAAACCCGCCGCCGATCGACCTGCCTGTGCCTTTCGCGCTGCTGCTCAATCTTGTGAGCGCTTCC
AATGCGCACGAGAAGGGCGTGCTTTGGGGCTTCATCTCGCGCTACGCGCCTGGCGTCACACCGCAGACGCATCCCGAACT
GGATCGGCTGACGGAATACGCCATCCGCTACTTCGATGATTTCGTGAAGCCCGCGAAGAAGTTCCGTGAACCGGATGCCG
TTGAACGACAGGCGCTCGAAGCTCTAAGGGACAAGTTCGCTGCCCTGCCTGAAGGCGCCGACGGAGAGGAGATCCAAAAC
CTAGTCCTCGACGTGGCGCGTGGTATCGAACGGTACCAGGACCACACCAAGCAAAGCCCGAGCGGTGGGCCGGGCGTTTC
CGTGGCCTTCTTCCAGATGCTCTATCAGGTTCTCCTGGGACAGGAGCGTGGGCCGCGGTTCGGCTCCTTCGCCGCCCTTT
ACGGCGTCACGGAGACGCGGGCGCTGATCGAAAAGGCGTTGGCCGGAGAGCTGGCAGGATAA

Upstream 100 bases:

>100_bases
ATGGCGCAGGTGGGCTTACACGCCAAGCGGTGAACCGGTCCCGAAACGCCGCCATCGCGGTGCCGGAGGCGGAACATCCA
TCATTTACCGGATACAGCAG

Downstream 100 bases:

>100_bases
TCATTCTTCTCCGTCTCCGCGAGGAGACGGGGAGGGCTATTGGCTAGCCCAGACAATTCGGGCAATCCAGTCCACTTCTT
CATGCCCGAGCACTCGGTTC

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MTITLGNALELTPEVLQAAAESKAWPFEEARKIVKRYEGRGFPETVLFETGYGPSGLPHIGTFGEVARTSMVRHAFRVIT
EDKVRTKILCFSDDMDGLRKVPDNVPNQEMLRAHLGKPLTRVPDPFSNQYPSFGAANNARLRAFLDQFGFEYEFASSTEY
YASGRFDATLLKVLERFDEVMAVMLPSLREERAQTYSPFLPIHPKTGVVMQVPIEERKLDAGTIVWRDPESGERFETLVT
GGHSKLQWKPDWAMRWAALGVDYEMSGKDLIDSVKLAAQICTVLDGTPPEGFNYELFLDEKGQKISKSKGNGLTIDEWLA
YAPTESLSLYMFQKPKTAKKLYFDVIPKAVDDYYSFLSAYSRQDWQNRLGNPVWHIHDGNPPPIDLPVPFALLLNLVSAS
NAHEKGVLWGFISRYAPGVTPQTHPELDRLTEYAIRYFDDFVKPAKKFREPDAVERQALEALRDKFAALPEGADGEEIQN
LVLDVARGIERYQDHTKQSPSGGPGVSVAFFQMLYQVLLGQERGPRFGSFAALYGVTETRALIEKALAGELAG

Sequences:

>Translated_553_residues
MTITLGNALELTPEVLQAAAESKAWPFEEARKIVKRYEGRGFPETVLFETGYGPSGLPHIGTFGEVARTSMVRHAFRVIT
EDKVRTKILCFSDDMDGLRKVPDNVPNQEMLRAHLGKPLTRVPDPFSNQYPSFGAANNARLRAFLDQFGFEYEFASSTEY
YASGRFDATLLKVLERFDEVMAVMLPSLREERAQTYSPFLPIHPKTGVVMQVPIEERKLDAGTIVWRDPESGERFETLVT
GGHSKLQWKPDWAMRWAALGVDYEMSGKDLIDSVKLAAQICTVLDGTPPEGFNYELFLDEKGQKISKSKGNGLTIDEWLA
YAPTESLSLYMFQKPKTAKKLYFDVIPKAVDDYYSFLSAYSRQDWQNRLGNPVWHIHDGNPPPIDLPVPFALLLNLVSAS
NAHEKGVLWGFISRYAPGVTPQTHPELDRLTEYAIRYFDDFVKPAKKFREPDAVERQALEALRDKFAALPEGADGEEIQN
LVLDVARGIERYQDHTKQSPSGGPGVSVAFFQMLYQVLLGQERGPRFGSFAALYGVTETRALIEKALAGELAG
>Mature_552_residues
TITLGNALELTPEVLQAAAESKAWPFEEARKIVKRYEGRGFPETVLFETGYGPSGLPHIGTFGEVARTSMVRHAFRVITE
DKVRTKILCFSDDMDGLRKVPDNVPNQEMLRAHLGKPLTRVPDPFSNQYPSFGAANNARLRAFLDQFGFEYEFASSTEYY
ASGRFDATLLKVLERFDEVMAVMLPSLREERAQTYSPFLPIHPKTGVVMQVPIEERKLDAGTIVWRDPESGERFETLVTG
GHSKLQWKPDWAMRWAALGVDYEMSGKDLIDSVKLAAQICTVLDGTPPEGFNYELFLDEKGQKISKSKGNGLTIDEWLAY
APTESLSLYMFQKPKTAKKLYFDVIPKAVDDYYSFLSAYSRQDWQNRLGNPVWHIHDGNPPPIDLPVPFALLLNLVSASN
AHEKGVLWGFISRYAPGVTPQTHPELDRLTEYAIRYFDDFVKPAKKFREPDAVERQALEALRDKFAALPEGADGEEIQNL
VLDVARGIERYQDHTKQSPSGGPGVSVAFFQMLYQVLLGQERGPRFGSFAALYGVTETRALIEKALAGELAG

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 62080; Mature: 61949

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITLGNALELTPEVLQAAAESKAWPFEEARKIVKRYEGRGFPETVLFETGYGPSGLPHI
CEEECCCCHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
GTFGEVARTSMVRHAFRVITEDKVRTKILCFSDDMDGLRKVPDNVPNQEMLRAHLGKPLT
CCHHHHHHHHHHHHHHHHHHHHCHHEEEEEECCCHHHHHHCCCCCCCHHHHHHHHCCCHH
RVPDPFSNQYPSFGAANNARLRAFLDQFGFEYEFASSTEYYASGRFDATLLKVLERFDEV
HCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCHHHCCCCHHHHHHHHHHHHHH
MAVMLPSLREERAQTYSPFLPIHPKTGVVMQVPIEERKLDAGTIVWRDPESGERFETLVT
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHCCCCCEEEECCCCCCCHHHHHHC
GGHSKLQWKPDWAMRWAALGVDYEMSGKDLIDSVKLAAQICTVLDGTPPEGFNYELFLDE
CCCCCEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
KGQKISKSKGNGLTIDEWLAYAPTESLSLYMFQKPKTAKKLYFDVIPKAVDDYYSFLSAY
CCCHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
SRQDWQNRLGNPVWHIHDGNPPPIDLPVPFALLLNLVSASNAHEKGVLWGFISRYAPGVT
HHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
PQTHPELDRLTEYAIRYFDDFVKPAKKFREPDAVERQALEALRDKFAALPEGADGEEIQN
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LVLDVARGIERYQDHTKQSPSGGPGVSVAFFQMLYQVLLGQERGPRFGSFAALYGVTETR
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ALIEKALAGELAG
HHHHHHHHHCCCC
>Mature Secondary Structure 
TITLGNALELTPEVLQAAAESKAWPFEEARKIVKRYEGRGFPETVLFETGYGPSGLPHI
EEECCCCHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
GTFGEVARTSMVRHAFRVITEDKVRTKILCFSDDMDGLRKVPDNVPNQEMLRAHLGKPLT
CCHHHHHHHHHHHHHHHHHHHHCHHEEEEEECCCHHHHHHCCCCCCCHHHHHHHHCCCHH
RVPDPFSNQYPSFGAANNARLRAFLDQFGFEYEFASSTEYYASGRFDATLLKVLERFDEV
HCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCHHHCCCCHHHHHHHHHHHHHH
MAVMLPSLREERAQTYSPFLPIHPKTGVVMQVPIEERKLDAGTIVWRDPESGERFETLVT
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHCCCCCEEEECCCCCCCHHHHHHC
GGHSKLQWKPDWAMRWAALGVDYEMSGKDLIDSVKLAAQICTVLDGTPPEGFNYELFLDE
CCCCCEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
KGQKISKSKGNGLTIDEWLAYAPTESLSLYMFQKPKTAKKLYFDVIPKAVDDYYSFLSAY
CCCHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
SRQDWQNRLGNPVWHIHDGNPPPIDLPVPFALLLNLVSASNAHEKGVLWGFISRYAPGVT
HHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
PQTHPELDRLTEYAIRYFDDFVKPAKKFREPDAVERQALEALRDKFAALPEGADGEEIQN
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LVLDVARGIERYQDHTKQSPSGGPGVSVAFFQMLYQVLLGQERGPRFGSFAALYGVTETR
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ALIEKALAGELAG
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]