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The map label for this gene is argD [H]

Identifier: 110632371

GI number: 110632371

Start: 8113

End: 9318

Strand: Reverse

Name: argD [H]

Synonym: Meso_0009

Alternate gene names: 110632371

Gene position: 9318-8113 (Counterclockwise)

Preceding gene: 110632373

Following gene: 110632370

Centisome position: 0.21

GC content: 60.86

Gene sequence:

>1206_bases
ATGAGCGGTTCGGCGCTTTTTGATACTTTTGCGAGGCTACCCCTTTCTTTCGAGCGGGGGGAAGGATCGTGGCTGATCAC
CGCCGACGGGACGCGATATCTAGATTTTGCCGCGGGAATAGCGGTCAATTCCCTGGGTCACGCCCATCCGCATCTGGTGG
CCGCCCTTACCGAGCAAGCCGGCAAGCTGTGGCACGTTTCAAATCTTTACGAGATTCCCGGTCAGCGCCGCCTGGGCGAG
CGGCTTGCCGAGCATAGCTTCGCAGACAAGGTGTTCTTCACCAATTCGGGCGCGGAGGCGCTCGAATGCGCCATCAAGAC
GGCGCGGCGCTATCATTACGTCAACGGGCAGGAAAACCGCTTCCGCATCATCACTTTCGAAGGCGCATTCCACGGCCGTA
CGCTTGCGACCATCGCTGCCGGCGGCCAGAAGAAATATCTGGAGGGCTTCGGTCCAAAGGTCGAAGGTTTTGACCAGTTG
CCCTTCGGGGATCTGCGGGCCGTTGAAAACGCCATCACACCCGAGACCGCCGCCATTCTCATTGAGCCGATCCAGGGTGA
GGGCGGCATCCGTATGCCCCCCGCCCAGTTCATTCAGGGATTGAGGGAACTCTGCGACAAGCATGGCCTGCTGCTGATCT
TCGACGAAGTTCAGACGGGGATCGGCCGCACCGGAAAGCTCTTTGCCTATGAATGGACTGGCGTAGCACCTGATATTGCG
GCCATCGCGAAAGGCATCGGAGGCGGTTTTCCGATGGGCGCGTGCCTGGCAACAGAGGAAGCCGCAAAGGGAATGACACC
AGGCGTGCACGGCACCACTTTCGGTGGCAATCCCCTCGCGATGGCGGTTGGAAACGCAGTGCTGGACGTGGTCCTGGAGC
CTGGCTTCCTCGATGAGGTGAGCCGCAGGGGCCTGCTCCTCAAGCAAGGCCTCGCCGCAATTGCCGACACCTTCCCCGAT
ATCGTGGACGAGATCCGCGGCACCGGGCTGCTGCTCGGAATCCGCTGCAAGAGCCCCACTTCCGCGCTGCAGCAGGCGCT
GCGCGAGGAGGGAATACTTGTGGCGCCGGCCGGAGAGAATGTGCTCCGCCTGCTGCCGCCGCTCAATGTCACTGATGAAG
ATATTCAGGAGGGGCTGGAGCGTATCCATCGCGCCATGGAAAGCTTGGTATCTGCGTCCTCAATTGCCACAGCGACAAAG
GTGTGA

Upstream 100 bases:

>100_bases
AATGCTGATAAAAAGGCCGCTTGCCGCCCTTGGGGCGGCATTTTGATTTCATCGGCATCGCGGCTTGGTGCCGTCGAGCA
GAATCCCGAGGAATGTGCGC

Downstream 100 bases:

>100_bases
CTGCCTTGGCACGCAATTTCATCGATCTTTCCGCCGTTTCTGCCGCCGATCTGCGGTCCATTCTGGACGATGCCAAGGAG
CGCAAGGCGCTGCTGAAATC

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSGSALFDTFARLPLSFERGEGSWLITADGTRYLDFAAGIAVNSLGHAHPHLVAALTEQAGKLWHVSNLYEIPGQRRLGE
RLAEHSFADKVFFTNSGAEALECAIKTARRYHYVNGQENRFRIITFEGAFHGRTLATIAAGGQKKYLEGFGPKVEGFDQL
PFGDLRAVENAITPETAAILIEPIQGEGGIRMPPAQFIQGLRELCDKHGLLLIFDEVQTGIGRTGKLFAYEWTGVAPDIA
AIAKGIGGGFPMGACLATEEAAKGMTPGVHGTTFGGNPLAMAVGNAVLDVVLEPGFLDEVSRRGLLLKQGLAAIADTFPD
IVDEIRGTGLLLGIRCKSPTSALQQALREEGILVAPAGENVLRLLPPLNVTDEDIQEGLERIHRAMESLVSASSIATATK
V

Sequences:

>Translated_401_residues
MSGSALFDTFARLPLSFERGEGSWLITADGTRYLDFAAGIAVNSLGHAHPHLVAALTEQAGKLWHVSNLYEIPGQRRLGE
RLAEHSFADKVFFTNSGAEALECAIKTARRYHYVNGQENRFRIITFEGAFHGRTLATIAAGGQKKYLEGFGPKVEGFDQL
PFGDLRAVENAITPETAAILIEPIQGEGGIRMPPAQFIQGLRELCDKHGLLLIFDEVQTGIGRTGKLFAYEWTGVAPDIA
AIAKGIGGGFPMGACLATEEAAKGMTPGVHGTTFGGNPLAMAVGNAVLDVVLEPGFLDEVSRRGLLLKQGLAAIADTFPD
IVDEIRGTGLLLGIRCKSPTSALQQALREEGILVAPAGENVLRLLPPLNVTDEDIQEGLERIHRAMESLVSASSIATATK
V
>Mature_400_residues
SGSALFDTFARLPLSFERGEGSWLITADGTRYLDFAAGIAVNSLGHAHPHLVAALTEQAGKLWHVSNLYEIPGQRRLGER
LAEHSFADKVFFTNSGAEALECAIKTARRYHYVNGQENRFRIITFEGAFHGRTLATIAAGGQKKYLEGFGPKVEGFDQLP
FGDLRAVENAITPETAAILIEPIQGEGGIRMPPAQFIQGLRELCDKHGLLLIFDEVQTGIGRTGKLFAYEWTGVAPDIAA
IAKGIGGGFPMGACLATEEAAKGMTPGVHGTTFGGNPLAMAVGNAVLDVVLEPGFLDEVSRRGLLLKQGLAAIADTFPDI
VDEIRGTGLLLGIRCKSPTSALQQALREEGILVAPAGENVLRLLPPLNVTDEDIQEGLERIHRAMESLVSASSIATATKV

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=389, Percent_Identity=35.2185089974293, Blast_Score=245, Evalue=5e-65,
Organism=Homo sapiens, GI284507298, Length=303, Percent_Identity=36.963696369637, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI13994255, Length=438, Percent_Identity=31.5068493150685, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI37574042, Length=433, Percent_Identity=28.175519630485, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI226442705, Length=433, Percent_Identity=27.4826789838337, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI24119277, Length=422, Percent_Identity=28.1990521327014, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI226442709, Length=398, Percent_Identity=28.391959798995, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI188536080, Length=416, Percent_Identity=23.5576923076923, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI38679950, Length=416, Percent_Identity=23.5576923076923, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI38679946, Length=416, Percent_Identity=23.5576923076923, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1788044, Length=393, Percent_Identity=45.8015267175573, Blast_Score=338, Evalue=5e-94,
Organism=Escherichia coli, GI1789759, Length=378, Percent_Identity=46.2962962962963, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=35.2941176470588, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1789016, Length=418, Percent_Identity=36.6028708133971, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1787560, Length=402, Percent_Identity=33.8308457711443, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1786991, Length=401, Percent_Identity=31.6708229426434, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1786349, Length=377, Percent_Identity=30.7692307692308, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25144271, Length=385, Percent_Identity=35.3246753246753, Blast_Score=241, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=31.3364055299539, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI25144274, Length=275, Percent_Identity=36, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=431, Percent_Identity=27.3781902552204, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17541228, Length=447, Percent_Identity=24.6085011185682, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71981843, Length=160, Percent_Identity=33.125, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=389, Percent_Identity=36.7609254498715, Blast_Score=260, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6323470, Length=404, Percent_Identity=34.4059405940594, Blast_Score=226, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6324386, Length=394, Percent_Identity=23.8578680203046, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=437, Percent_Identity=25.1716247139588, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21357415, Length=384, Percent_Identity=35.4166666666667, Blast_Score=241, Evalue=9e-64,
Organism=Drosophila melanogaster, GI161085790, Length=437, Percent_Identity=30.8924485125858, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI28574759, Length=418, Percent_Identity=31.1004784688995, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI21356575, Length=411, Percent_Identity=29.1970802919708, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281366494, Length=436, Percent_Identity=26.3761467889908, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24667139, Length=436, Percent_Identity=26.3761467889908, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24667143, Length=436, Percent_Identity=26.3761467889908, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42825; Mature: 42693

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSALFDTFARLPLSFERGEGSWLITADGTRYLDFAAGIAVNSLGHAHPHLVAALTEQA
CCCHHHHHHHHHCCCEEECCCCCEEEEECCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHC
GKLWHVSNLYEIPGQRRLGERLAEHSFADKVFFTNSGAEALECAIKTARRYHYVNGQENR
CCEEEECHHHHCCCHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHEEECCCCCCE
FRIITFEGAFHGRTLATIAAGGQKKYLEGFGPKVEGFDQLPFGDLRAVENAITPETAAIL
EEEEEEECCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEE
IEPIQGEGGIRMPPAQFIQGLRELCDKHGLLLIFDEVQTGIGRTGKLFAYEWTGVAPDIA
EEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECHHHCCCCCCCEEEEECCCCCHHHH
AIAKGIGGGFPMGACLATEEAAKGMTPGVHGTTFGGNPLAMAVGNAVLDVVLEPGFLDEV
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
SRRGLLLKQGLAAIADTFPDIVDEIRGTGLLLGIRCKSPTSALQQALREEGILVAPAGEN
HHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHCCEEEEECCCC
VLRLLPPLNVTDEDIQEGLERIHRAMESLVSASSIATATKV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGSALFDTFARLPLSFERGEGSWLITADGTRYLDFAAGIAVNSLGHAHPHLVAALTEQA
CCHHHHHHHHHCCCEEECCCCCEEEEECCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHC
GKLWHVSNLYEIPGQRRLGERLAEHSFADKVFFTNSGAEALECAIKTARRYHYVNGQENR
CCEEEECHHHHCCCHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHEEECCCCCCE
FRIITFEGAFHGRTLATIAAGGQKKYLEGFGPKVEGFDQLPFGDLRAVENAITPETAAIL
EEEEEEECCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEE
IEPIQGEGGIRMPPAQFIQGLRELCDKHGLLLIFDEVQTGIGRTGKLFAYEWTGVAPDIA
EEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECHHHCCCCCCCEEEEECCCCCHHHH
AIAKGIGGGFPMGACLATEEAAKGMTPGVHGTTFGGNPLAMAVGNAVLDVVLEPGFLDEV
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
SRRGLLLKQGLAAIADTFPDIVDEIRGTGLLLGIRCKSPTSALQQALREEGILVAPAGEN
HHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHCCEEEEECCCC
VLRLLPPLNVTDEDIQEGLERIHRAMESLVSASSIATATKV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]