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The map label for this gene is hslO [H]

Identifier: 110632369

GI number: 110632369

Start: 6186

End: 7202

Strand: Reverse

Name: hslO [H]

Synonym: Meso_0007

Alternate gene names: 110632369

Gene position: 7202-6186 (Counterclockwise)

Preceding gene: 110632370

Following gene: 110632368

Centisome position: 0.16

GC content: 61.75

Gene sequence:

>1017_bases
GTGAACGACGATACGGCGAAATTGGGCGACTTCGGCTTCGCCGGAGACGATCACGTCGTGCCTTTCGAGGTGGAGATGCT
CGACGTGCGCGGGCGCGCCGTGCAGGTTGGTGCGATGCTCGACCAGATTCTGGAGCGTCATGCCTATCCGGAGCCAGTCG
CGCGGCTCTTGGCCGAAGTGATCGTTCTGACGGTCCTTCTCGGCAGCTCGCTGAAATTCGACGGTAAGTTCATCGTCCAG
ACGCGTTCCGACGGCCCGGTCGACATGCTGGTGGCCGACTTCTCCACGCCCGGTTCAGTGCGTGCCTATGCCCGGTTCGA
TGAGGCTCGGCTCGCCGACGCAGTCGAGCAGGGGGCGGCTTCGCCAGAGGCATTGCTCGGAGAGGGCATCCTGGCGCTTA
CGATCGACCAAGGACCCTATACGCAGCGTTATCAGGGCATAGTGCAGCTAGACGGCTCTACATTGGAGGACGTGGCGCGC
AGCTATTTCCGCCAGTCGGAGCAGATCCCGACCGAAGTGCGCCTTGGCGTGGCTCGCATTGTCATGCCGGGCGAGAGCGG
AAAGGGGCGCTGGCGCGCCGGCGGACTGCTTGTCCAGTTCCTGCCCTCCGTGCCCGAACGTGCCCGCATGGGCGATCTAC
CGGGCGGCGACGGCGACGAAGAGAACGAGGGCAACGGCCACCCCGACGACAATGCCTGGCAGGAGGCACTGGCGCTTCTG
AACACCGTCGAAGTCGACGAGCTTCTAGATCCCACCGTCGGCGCTGAAAGGCTTCTCTATCGCCTGTTCCACGAGCAGGG
CGTGCGCGTCTATGACGGCGTGGACGTGATCGACAACTGCTCCTGCTCGCGTGAGAAAATCAAAACCATCCTCGATGGCT
TCACTGCCGAGGAAATCAAGGAAAGCACCGAAGACGGCATCATTCGCGTCAACTGCGAATTCTGTTCGAAGGAATATCTC
TTCGATCCCAAGGAATTCGATGGGGCGCAGGATTCCAAGGCTCAGTCAGAAGACTGA

Upstream 100 bases:

>100_bases
TGACCGACGGCGTTATCGACGGCCCCCACTCGGTGGTGTTCGACGAGGCGGAGAACCGCTTGCACGCCCAGAAAGCCGTT
CTCGCCTGGTGCCTCGGCCA

Downstream 100 bases:

>100_bases
CGCCCTGCTTAGAAGACGGGTCGTTCCACCGCGCCATACGAAAATCGATCTCCAGCGCTAGCAGGCCCGGGATATCTCTG
AAATCACGCCCTTTTACCGC

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33 [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNDDTAKLGDFGFAGDDHVVPFEVEMLDVRGRAVQVGAMLDQILERHAYPEPVARLLAEVIVLTVLLGSSLKFDGKFIVQ
TRSDGPVDMLVADFSTPGSVRAYARFDEARLADAVEQGAASPEALLGEGILALTIDQGPYTQRYQGIVQLDGSTLEDVAR
SYFRQSEQIPTEVRLGVARIVMPGESGKGRWRAGGLLVQFLPSVPERARMGDLPGGDGDEENEGNGHPDDNAWQEALALL
NTVEVDELLDPTVGAERLLYRLFHEQGVRVYDGVDVIDNCSCSREKIKTILDGFTAEEIKESTEDGIIRVNCEFCSKEYL
FDPKEFDGAQDSKAQSED

Sequences:

>Translated_338_residues
MNDDTAKLGDFGFAGDDHVVPFEVEMLDVRGRAVQVGAMLDQILERHAYPEPVARLLAEVIVLTVLLGSSLKFDGKFIVQ
TRSDGPVDMLVADFSTPGSVRAYARFDEARLADAVEQGAASPEALLGEGILALTIDQGPYTQRYQGIVQLDGSTLEDVAR
SYFRQSEQIPTEVRLGVARIVMPGESGKGRWRAGGLLVQFLPSVPERARMGDLPGGDGDEENEGNGHPDDNAWQEALALL
NTVEVDELLDPTVGAERLLYRLFHEQGVRVYDGVDVIDNCSCSREKIKTILDGFTAEEIKESTEDGIIRVNCEFCSKEYL
FDPKEFDGAQDSKAQSED
>Mature_338_residues
MNDDTAKLGDFGFAGDDHVVPFEVEMLDVRGRAVQVGAMLDQILERHAYPEPVARLLAEVIVLTVLLGSSLKFDGKFIVQ
TRSDGPVDMLVADFSTPGSVRAYARFDEARLADAVEQGAASPEALLGEGILALTIDQGPYTQRYQGIVQLDGSTLEDVAR
SYFRQSEQIPTEVRLGVARIVMPGESGKGRWRAGGLLVQFLPSVPERARMGDLPGGDGDEENEGNGHPDDNAWQEALALL
NTVEVDELLDPTVGAERLLYRLFHEQGVRVYDGVDVIDNCSCSREKIKTILDGFTAEEIKESTEDGIIRVNCEFCSKEYL
FDPKEFDGAQDSKAQSED

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress [H]

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family [H]

Homologues:

Organism=Escherichia coli, GI87082260, Length=311, Percent_Identity=34.4051446945338, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153 [H]

Pfam domain/function: PF01430 HSP33 [H]

EC number: NA

Molecular weight: Translated: 37046; Mature: 37046

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDDTAKLGDFGFAGDDHVVPFEVEMLDVRGRAVQVGAMLDQILERHAYPEPVARLLAEV
CCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHH
IVLTVLLGSSLKFDGKFIVQTRSDGPVDMLVADFSTPGSVRAYARFDEARLADAVEQGAA
HHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCC
SPEALLGEGILALTIDQGPYTQRYQGIVQLDGSTLEDVARSYFRQSEQIPTEVRLGVARI
CCHHHHCCCEEEEEECCCCCHHHHCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHCEEEE
VMPGESGKGRWRAGGLLVQFLPSVPERARMGDLPGGDGDEENEGNGHPDDNAWQEALALL
EECCCCCCCCEECCCHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
NTVEVDELLDPTVGAERLLYRLFHEQGVRVYDGVDVIDNCSCSREKIKTILDGFTAEEIK
HHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCHHHCCCCCHHHHHHHHCCCCHHHHH
ESTEDGIIRVNCEFCSKEYLFDPKEFDGAQDSKAQSED
HHCCCCEEEEEHHHHCHHHCCCCHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNDDTAKLGDFGFAGDDHVVPFEVEMLDVRGRAVQVGAMLDQILERHAYPEPVARLLAEV
CCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHH
IVLTVLLGSSLKFDGKFIVQTRSDGPVDMLVADFSTPGSVRAYARFDEARLADAVEQGAA
HHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCC
SPEALLGEGILALTIDQGPYTQRYQGIVQLDGSTLEDVARSYFRQSEQIPTEVRLGVARI
CCHHHHCCCEEEEEECCCCCHHHHCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHCEEEE
VMPGESGKGRWRAGGLLVQFLPSVPERARMGDLPGGDGDEENEGNGHPDDNAWQEALALL
EECCCCCCCCEECCCHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
NTVEVDELLDPTVGAERLLYRLFHEQGVRVYDGVDVIDNCSCSREKIKTILDGFTAEEIK
HHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCHHHCCCCCHHHHHHHHCCCCHHHHH
ESTEDGIIRVNCEFCSKEYLFDPKEFDGAQDSKAQSED
HHCCCCEEEEEHHHHCHHHCCCCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA