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The map label for this gene is yabD [H]

Identifier: 109948154

GI number: 109948154

Start: 1462024

End: 1462788

Strand: Reverse

Name: yabD [H]

Synonym: Hac_1680

Alternate gene names: 109948154

Gene position: 1462788-1462024 (Counterclockwise)

Preceding gene: 109948161

Following gene: 109948153

Centisome position: 94.13

GC content: 37.12

Gene sequence:

>765_bases
ATGTTTATTGATACGCACTGCCATCTAGACCACAAGGATTATGAAAACGATTTAGAAGAAGTGTTAAAAGAAAGCTTAGA
AAAAGGCGTTTCTAAATGCGTGATTCCAGGTGCGGACATGAAAGATTTGAATAAAGCAATAGAGATTAGCGAAAAACATG
AAGGCGTGTTTTTTGCCATAGGTGCTCATCCTTATGATGCGGATAGCTTTGATGAAAGCTTGTTTGAAGCGTTTGTTGGG
CATGAAAAATGCGTGGCGATAGGCGAATGCGGATTGGATTACTACCGCTTGCCTAAATTGAATGAAAGAGAAAATTACAA
AAACAAACAAAAAGAAATTTTTACAAAACAAATTGAATTTTCTGTCAAACACAAGAAGCCTTTGATTGTCCACATTAGAG
AAGCGAGTTTTGATAGTTTGAATCTTTTAAAAAATTATCCTAAAGCTTTTGGGGTGTTGCATTGTTTTAATGCTGATGGC
ATGCTTTTGGAATTGAGCGATCGTTTTTATTATGGGATAGGGGGGGTTAGCACTTTTAAGAATGCTAAAAGGTTGGTAGA
AATCCTCCCTAAAATCCCTAAAAACAGGCTTCTTTTAGAAACGGATTCGCCTTATTTGACCCCACACCCTTTTAGAGGCA
CTAGAAATAGCCCTACTTATATCCCTTTAATCGCTCAAAAAATTGCCGAAATAATTAATATAGAGACTGAAGAGCTCGCT
TCTTTAAGCACGCATAACGCCCAAACGCTCTTTAACTTCCCTTAA

Upstream 100 bases:

>100_bases
CTATTTTATGGATTAACCCACTAAACATAATTGGTTGTTATTTTCCTTATGTTAAAATGCTCAGTTATTATAACATATTA
AATAAAACCATAGGATAAGC

Downstream 100 bases:

>100_bases
AAGTAAAGTTGTATTTAAAAAAGTATTATTCAAGTTTGGTATAATTAGAGCCATTATTAAACTTATCAAATTATTAGGAT
TTTAAAAAAGAATGAAATAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MFIDTHCHLDHKDYENDLEEVLKESLEKGVSKCVIPGADMKDLNKAIEISEKHEGVFFAIGAHPYDADSFDESLFEAFVG
HEKCVAIGECGLDYYRLPKLNERENYKNKQKEIFTKQIEFSVKHKKPLIVHIREASFDSLNLLKNYPKAFGVLHCFNADG
MLLELSDRFYYGIGGVSTFKNAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPTYIPLIAQKIAEIINIETEELA
SLSTHNAQTLFNFP

Sequences:

>Translated_254_residues
MFIDTHCHLDHKDYENDLEEVLKESLEKGVSKCVIPGADMKDLNKAIEISEKHEGVFFAIGAHPYDADSFDESLFEAFVG
HEKCVAIGECGLDYYRLPKLNERENYKNKQKEIFTKQIEFSVKHKKPLIVHIREASFDSLNLLKNYPKAFGVLHCFNADG
MLLELSDRFYYGIGGVSTFKNAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPTYIPLIAQKIAEIINIETEELA
SLSTHNAQTLFNFP
>Mature_254_residues
MFIDTHCHLDHKDYENDLEEVLKESLEKGVSKCVIPGADMKDLNKAIEISEKHEGVFFAIGAHPYDADSFDESLFEAFVG
HEKCVAIGECGLDYYRLPKLNERENYKNKQKEIFTKQIEFSVKHKKPLIVHIREASFDSLNLLKNYPKAFGVLHCFNADG
MLLELSDRFYYGIGGVSTFKNAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPTYIPLIAQKIAEIINIETEELA
SLSTHNAQTLFNFP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=262, Percent_Identity=27.4809160305344, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI110349734, Length=264, Percent_Identity=28.030303030303, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=27.5735294117647, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI225903424, Length=262, Percent_Identity=29.3893129770992, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI14042943, Length=280, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI226061614, Length=251, Percent_Identity=26.2948207171315, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI225903439, Length=258, Percent_Identity=28.2945736434109, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=26.2008733624454, Blast_Score=78, Evalue=6e-15,
Organism=Escherichia coli, GI1787342, Length=262, Percent_Identity=35.4961832061069, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI48994985, Length=266, Percent_Identity=29.3233082706767, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082439, Length=266, Percent_Identity=29.3233082706767, Blast_Score=117, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=288, Percent_Identity=29.1666666666667, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=29.7709923664122, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17565396, Length=304, Percent_Identity=26.6447368421053, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17543026, Length=193, Percent_Identity=29.0155440414508, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648690, Length=290, Percent_Identity=29.3103448275862, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI221330018, Length=291, Percent_Identity=27.8350515463918, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24586117, Length=291, Percent_Identity=27.8350515463918, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29037; Mature: 29037

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDTHCHLDHKDYENDLEEVLKESLEKGVSKCVIPGADMKDLNKAIEISEKHEGVFFAI
CEECCEECCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCCCCEEEEE
GAHPYDADSFDESLFEAFVGHEKCVAIGECGLDYYRLPKLNERENYKNKQKEIFTKQIEF
CCCCCCCCHHHHHHHHHHHCCHHEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHE
SVKHKKPLIVHIREASFDSLNLLKNYPKAFGVLHCFNADGMLLELSDRFYYGIGGVSTFK
EECCCCCEEEEEECCCCCHHHHHHHCHHHHCEEEEECCCCEEEEECCCEEECCCCHHHHH
NAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPTYIPLIAQKIAEIINIETEELA
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHH
SLSTHNAQTLFNFP
HHHCCCCCEEECCC
>Mature Secondary Structure
MFIDTHCHLDHKDYENDLEEVLKESLEKGVSKCVIPGADMKDLNKAIEISEKHEGVFFAI
CEECCEECCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCCCCEEEEE
GAHPYDADSFDESLFEAFVGHEKCVAIGECGLDYYRLPKLNERENYKNKQKEIFTKQIEF
CCCCCCCCHHHHHHHHHHHCCHHEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHE
SVKHKKPLIVHIREASFDSLNLLKNYPKAFGVLHCFNADGMLLELSDRFYYGIGGVSTFK
EECCCCCEEEEEECCCCCHHHHHHHCHHHHCEEEEECCCCEEEEECCCEEECCCCHHHHH
NAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPTYIPLIAQKIAEIINIETEELA
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHH
SLSTHNAQTLFNFP
HHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]