Click here to switch to the map view.

The map label for this gene is coaX [H]

Identifier: 109947750

GI number: 109947750

Start: 1060527

End: 1061192

Strand: Reverse

Name: coaX [H]

Synonym: Hac_1225

Alternate gene names: 109947750

Gene position: 1061192-1060527 (Counterclockwise)

Preceding gene: 109947751

Following gene: 109947749

Centisome position: 68.29

GC content: 37.84

Gene sequence:

>666_bases
ATGCCAGAATGTTTTAAAGAAGCAAAAGATTTGATTTTATGCGATATAGGTAATACATGCATCCATTTTGCACAAGGCTA
TCAGCTCTTTTCAAGCGCTAAAGAAGATTTAAAGCGTTTGGATATTCAAAAAGAAATTTTTTACATTAGCGTGAACGAAG
AAAATGAAAAAGCCCTTTTAGATTGTTACCCTAACGCTAAAAATATTGCAGGATTTTTTCATTTAGAAACCGATTATATA
GGGCTTGGGATAGACCGGCAAATGGCGTGTTTAGCGGTGGCAAATGGCGTGGTGGTGGATGCGGGGAGTGCAATTACGAT
AGATTTAATCAAAGATAGTAAGCATTTAGGGGGGTGTATTTTACCTGGGTTAGCCCAATATACCCATGCGTATAGAAAAA
GCGCGAAAATTTTAGAGCAACCTTTCAAAGCCTTAGATTCTTTAGAAATTTTACCCAAAAATACTAGAGACGCTGTGAAT
TATGGCATGATTTTGAGCGTGATTGCTTGTATCCAACATTTAGCCAAAGATCAAAAAATCTATCTTTGTGGGGGCGATGC
GAAATTTTTGAGCGCGTTTTTAGTGCATTCTGTTTGTAAGGAGCGCTTGGTTTTTGATGGGATGGAGATCGCTCTTAAAA
AAGCGGGGATATTGGAATGCAAATGA

Upstream 100 bases:

>100_bases
CAAAGGGGTAGGGAATTTGAACAAAGAGCGAGGGAGCAACAAGAAAGAGATGAAAAAGAGCTTGAAGAAAAAAGAAAGGC
TTTAAAAGCGAAGTGATCCC

Downstream 100 bases:

>100_bases
TGCAAAATCTGAGTTTTTTAGGCATGTTTTTAGCCGCCTTGAGCATGTCTTTAGGGCATTGTGTGGGCATGTGTGGGGGG
ATTGTGAGCGCGTTTAGTCA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MPECFKEAKDLILCDIGNTCIHFAQGYQLFSSAKEDLKRLDIQKEIFYISVNEENEKALLDCYPNAKNIAGFFHLETDYI
GLGIDRQMACLAVANGVVVDAGSAITIDLIKDSKHLGGCILPGLAQYTHAYRKSAKILEQPFKALDSLEILPKNTRDAVN
YGMILSVIACIQHLAKDQKIYLCGGDAKFLSAFLVHSVCKERLVFDGMEIALKKAGILECK

Sequences:

>Translated_221_residues
MPECFKEAKDLILCDIGNTCIHFAQGYQLFSSAKEDLKRLDIQKEIFYISVNEENEKALLDCYPNAKNIAGFFHLETDYI
GLGIDRQMACLAVANGVVVDAGSAITIDLIKDSKHLGGCILPGLAQYTHAYRKSAKILEQPFKALDSLEILPKNTRDAVN
YGMILSVIACIQHLAKDQKIYLCGGDAKFLSAFLVHSVCKERLVFDGMEIALKKAGILECK
>Mature_220_residues
PECFKEAKDLILCDIGNTCIHFAQGYQLFSSAKEDLKRLDIQKEIFYISVNEENEKALLDCYPNAKNIAGFFHLETDYIG
LGIDRQMACLAVANGVVVDAGSAITIDLIKDSKHLGGCILPGLAQYTHAYRKSAKILEQPFKALDSLEILPKNTRDAVNY
GMILSVIACIQHLAKDQKIYLCGGDAKFLSAFLVHSVCKERLVFDGMEIALKKAGILECK

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 24453; Mature: 24322

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPECFKEAKDLILCDIGNTCIHFAQGYQLFSSAKEDLKRLDIQKEIFYISVNEENEKALL
CCHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEE
DCYPNAKNIAGFFHLETDYIGLGIDRQMACLAVANGVVVDAGSAITIDLIKDSKHLGGCI
EECCCCCCCEEEEEEECCEEECCCCHHHHHHHHHCCEEEECCCEEEEEEEECCCCCCCCH
LPGLAQYTHAYRKSAKILEQPFKALDSLEILPKNTRDAVNYGMILSVIACIQHLAKDQKI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
YLCGGDAKFLSAFLVHSVCKERLVFDGMEIALKKAGILECK
EEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
PECFKEAKDLILCDIGNTCIHFAQGYQLFSSAKEDLKRLDIQKEIFYISVNEENEKALL
CHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEE
DCYPNAKNIAGFFHLETDYIGLGIDRQMACLAVANGVVVDAGSAITIDLIKDSKHLGGCI
EECCCCCCCEEEEEEECCEEECCCCHHHHHHHHHCCEEEECCCEEEEEEEECCCCCCCCH
LPGLAQYTHAYRKSAKILEQPFKALDSLEILPKNTRDAVNYGMILSVIACIQHLAKDQKI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
YLCGGDAKFLSAFLVHSVCKERLVFDGMEIALKKAGILECK
EEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA