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The map label for this gene is yqhT [H]

Identifier: 109947673

GI number: 109947673

Start: 990240

End: 991313

Strand: Reverse

Name: yqhT [H]

Synonym: Hac_1141

Alternate gene names: 109947673

Gene position: 991313-990240 (Counterclockwise)

Preceding gene: 109947674

Following gene: 109947672

Centisome position: 63.79

GC content: 39.66

Gene sequence:

>1074_bases
ATGAAAGGATTAGAAAGAGGATCGCATTTCACGCTCAATGAAAATGCGATGTTTTTTGAGTGTGCTTATAGTTGCGATAA
TGCTTTGTTTTTGCAATTAAACGATCGCTCGTTTTTTATCACTGATTCTCGCTACACTCAAGAGGCTAGAGAAAGTATTC
AGCCTAAAAATGGCGTTTTAGCGGAAGTAATAGAGTCTAGTGATTTAGTGCAAAGTGCGATTGATTTGATTATAAAAAGC
TCTGTTAAAAAGCTCTTTTTTGACCCTAATCAGGTGAATTTACAAACCTATAAGCGTTTGGATTCAGCGATTGGTGCTAA
AGTGAGTTTAGAGGGCGTGCCCAGTTACCACCGTCAAAAACGCATCATTAAAAATGAGCATGAGATCCAACTTCTCAAAA
AATCTCAAGCCTTGAATGTTGAAGCTTTTGAAAATTTTGCCGAGTATGTGAAGAATATTTTTGATGAAAAAGAGTCCTTG
AGCGAGCGGTATTTGCAGCATAAGGTTAAAGACTTTTTGACTAGAGAAGGGGTTTATGATTTGAGTTTTGAACCTATCTT
AGCCTTGAATGCGAATGCGAGCAAACCCCATGCCTTGCCTAGTGCTAAGGATTTTTTAAAAGCGGAGCATAGCATTCTTT
TGGATATGGGGATCAAATACGAGCGTTATTGCTCTGATAGGACCCGCACGGCTTTTTTTGACCCAAAAGACTTTGTGTTT
AAAAGAGAGCAAAGTTTTAAGGATAAAGAGCGTCAAAAGATTTATGATATTGTCAAAGAAACGCAAGAAAAGGCTATTGC
AGGCATTAGAGCGGGCATGACCGGTAAAGAAGCGGACAGCTTGGCTAGGGGAGTGATTAGTGAGTATGGCTATGGGCAAT
ATTTCACTCACAGCACTGGGCATGGCATTGGTTTAGACATTCATGAGCTCCCTTATATTTCATCGCACAGTGAAACCATT
TTAGAAGAAGGCATGGTGTTTTCTGTGGAGCCTGGGATTTATATCCCTGGATTTTTTGGGGTGCGCATTGAAGATTTAGT
CGTGATTAAAAATTCTAGGGCTGAGCTTTTGTGA

Upstream 100 bases:

>100_bases
GAATATTCTAGCCGAGATGAAAGCTTTCCAAGAAGCCCAACAAAACAACCCCAATAACTCGATCAACAATATCAATAACT
AACCAGAAAGGGGGCTACCC

Downstream 100 bases:

>100_bases
TGCAAGAGATCCTTACTAGCCACTTTTTCCCTAGCCTTTTTAAAAGAAGACTTGATTTTTCTAACAGAGTGGTTTTAGGG
TTGGGATCTAATATTAAAAA

Product: proline peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKGLERGSHFTLNENAMFFECAYSCDNALFLQLNDRSFFITDSRYTQEARESIQPKNGVLAEVIESSDLVQSAIDLIIKS
SVKKLFFDPNQVNLQTYKRLDSAIGAKVSLEGVPSYHRQKRIIKNEHEIQLLKKSQALNVEAFENFAEYVKNIFDEKESL
SERYLQHKVKDFLTREGVYDLSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
KREQSFKDKERQKIYDIVKETQEKAIAGIRAGMTGKEADSLARGVISEYGYGQYFTHSTGHGIGLDIHELPYISSHSETI
LEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRAELL

Sequences:

>Translated_357_residues
MKGLERGSHFTLNENAMFFECAYSCDNALFLQLNDRSFFITDSRYTQEARESIQPKNGVLAEVIESSDLVQSAIDLIIKS
SVKKLFFDPNQVNLQTYKRLDSAIGAKVSLEGVPSYHRQKRIIKNEHEIQLLKKSQALNVEAFENFAEYVKNIFDEKESL
SERYLQHKVKDFLTREGVYDLSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
KREQSFKDKERQKIYDIVKETQEKAIAGIRAGMTGKEADSLARGVISEYGYGQYFTHSTGHGIGLDIHELPYISSHSETI
LEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRAELL
>Mature_357_residues
MKGLERGSHFTLNENAMFFECAYSCDNALFLQLNDRSFFITDSRYTQEARESIQPKNGVLAEVIESSDLVQSAIDLIIKS
SVKKLFFDPNQVNLQTYKRLDSAIGAKVSLEGVPSYHRQKRIIKNEHEIQLLKKSQALNVEAFENFAEYVKNIFDEKESL
SERYLQHKVKDFLTREGVYDLSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
KREQSFKDKERQKIYDIVKETQEKAIAGIRAGMTGKEADSLARGVISEYGYGQYFTHSTGHGIGLDIHELPYISSHSETI
LEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRAELL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=279, Percent_Identity=25.4480286738351, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI264681563, Length=257, Percent_Identity=26.4591439688716, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI93141226, Length=242, Percent_Identity=28.5123966942149, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788728, Length=324, Percent_Identity=32.4074074074074, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789275, Length=310, Percent_Identity=25.1612903225806, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17509539, Length=363, Percent_Identity=26.4462809917355, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320922, Length=253, Percent_Identity=23.7154150197628, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6321118, Length=252, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40746; Mature: 40746

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLERGSHFTLNENAMFFECAYSCDNALFLQLNDRSFFITDSRYTQEARESIQPKNGVL
CCCCCCCCCEEECCCCEEEEEEECCCCEEEEEECCCEEEEECCHHHHHHHHHCCCCCCHH
AEVIESSDLVQSAIDLIIKSSVKKLFFDPNQVNLQTYKRLDSAIGAKVSLEGVPSYHRQK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHH
RIIKNEHEIQLLKKSQALNVEAFENFAEYVKNIFDEKESLSERYLQHKVKDFLTREGVYD
HHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
CCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEECCCHHHHH
KREQSFKDKERQKIYDIVKETQEKAIAGIRAGMTGKEADSLARGVISEYGYGQYFTHSTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEECCCC
HGIGLDIHELPYISSHSETILEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRAELL
CCCCCCHHHCCCCCCCHHHHHHCCCEEEECCCEEECCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure
MKGLERGSHFTLNENAMFFECAYSCDNALFLQLNDRSFFITDSRYTQEARESIQPKNGVL
CCCCCCCCCEEECCCCEEEEEEECCCCEEEEEECCCEEEEECCHHHHHHHHHCCCCCCHH
AEVIESSDLVQSAIDLIIKSSVKKLFFDPNQVNLQTYKRLDSAIGAKVSLEGVPSYHRQK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHH
RIIKNEHEIQLLKKSQALNVEAFENFAEYVKNIFDEKESLSERYLQHKVKDFLTREGVYD
HHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
CCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEECCCHHHHH
KREQSFKDKERQKIYDIVKETQEKAIAGIRAGMTGKEADSLARGVISEYGYGQYFTHSTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEECCCC
HGIGLDIHELPYISSHSETILEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRAELL
CCCCCCHHHCCCCCCCHHHHHHCCCEEEECCCEEECCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]