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The map label for this gene is proWX [H]

Identifier: 109947293

GI number: 109947293

Start: 631980

End: 633635

Strand: Direct

Name: proWX [H]

Synonym: Hac_0721

Alternate gene names: 109947293

Gene position: 631980-633635 (Clockwise)

Preceding gene: 109947292

Following gene: 109947294

Centisome position: 40.67

GC content: 38.59

Gene sequence:

>1656_bases
ATGCTGATCATGGGCGTTTTTAAACAATTGATCAAAGAATTGTATGAATGGTTGATCCATTCTGTGGATGTGGCTATACA
ACATTTAGTTGCAATGGTGTTAAAGATAAGCGTGGTAAAATATTTGATAAAAGAATTTCATGATCGCTTTATTTATTTTA
TAGATTTAATTGCACAGCATTTTATCATCGTTTCGCTTTCTGGTCTTATCGTGTTGGTGTTTGGGGTTTTGATTGGGGTT
TTTGTGTTTTACAATTCAAAGGCTAGGGTCTTTTTACTCCCTGTGGTGAATTTTCTCTACACGATCCCTTCGCTGGCACT
ATTTGCGTTATTCATCCCTTTGATTGGGGTGGGGTTAAAAAACGCCCTTTTAGTGTTGGTCTTATACGGCTTATTACCCA
TTGTCCATAGCACTTATAACGCCTTAAAAGAGGTGAGAGAGGAAGTCATTAAGGCCGCCATTGGGCTAGGGTGTAACCCC
AAAGAGTTGTTTTTTAGGGTGCGATTTTTACTTGCTATCCCCCAAATTTTAGTGGGCTTAAGGATTGCGGTGGTGATGTT
AGTGGCGATGGCTGGGATTGGAGCACTCATTGGGGCTGGGGGATTAGGGCAAGCGATTTTTAGAGGGCTAAACACACAAA
ATACCACGCTTTTAGTGGCGGGTAGTTTTATTATTGCGGTTTTTAGTGTTTTAGCGGATAAATTTGTGAGCGTGTTTCAG
CATGAAAACGCCTTGCAACACCTGCTTTCTCAAAACGCCACCAAAAAACAAAAAAGAAGAGTTTATGTTAGTGTGGCGGT
ATTCCTCTTTTTATTACTAGCGAGTATATTATGGCTAGTGCCTAGAAGCGTTATAGAAGAAAAGCCTTTAGTCGTGGCGG
CAAAACCTAGCAGCGAGCAGTATATTTTGGGCGAGATTTTAAGCCTTTTGTTAGAAAAACACCATATTCCTGTTAAGCGA
GTGTTTGGCATTGGTGGGGGGACGATGAATATCCATCCGGCATTAATTAGGGGCGATTTTGATTTGTATGTGGAATATAC
CGGCACCGCTTGGGTGAATACGCTCAAAAACCCTTTGACTCAAAAAGTGGATTTTGAAACGATTAAAAGGCGTTATGAGA
AAGAATTTAATCTTTTATGGGTGGGGCTTTTGGGCTTTAATAACACCTATTCCTTAGCGATTTCTAAAGAGGACGCTCAA
AAATACGCTGTTGAAACTTTTAGCGATTTAGCCTTTCATAGCCCAAATTTTGATTTTGGCGCGGAGTTTGACTTTTTTGA
AAGAGAGGACGCTTTTAAGGGCTTAGTGAAAGCCTATCGCTTTCATTTTAGAAGTTTGCATGAAATGGATATTAACTTGC
GTTATAAAAGTTTTGAATCCCATAAAATCAACGCTTTAGATGTCTTCACTACAGACGCTCAAATCAAAGAGCTTGATTTG
AAGGTGCTTAGAGACGATAAAGGATTTTTCCCTAATTATCAAGCCGGTATTGTCATAAGAAAAGAAATTGTCAAAAAATA
TCCTAAAGTGTTAGAAATCTTAGAAAAAATAAAGATCAGCGATGAAAAAATGCAAGATTTAAACTATCAGGTGGAAGTGT
TGAAAAAAAGCCCCCAAATAGTAGCTAAAGATTTTTTAGAAAACATGGGGCTATAA

Upstream 100 bases:

>100_bases
CCAATTTAGGCAAACGAACCTTTCAATTTTAACTTGCAACCAACATTAAAGAATGCCTTTAGCATTTTAAGACACCTTTA
TTAGAATAAGTTTGGTTATA

Downstream 100 bases:

>100_bases
AACATGAAAGAAATCATTAAAATAGAGAATTTATCTTTTAACTACCACAATCGTGCAATTTTTAAAGATTTTAATTTAAG
TATTGAAGAAGGGGATTTTT

Product: osmoprotection protein

Products: NA

Alternate protein names: Osmoprotectant-binding protein [H]

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MLIMGVFKQLIKELYEWLIHSVDVAIQHLVAMVLKISVVKYLIKEFHDRFIYFIDLIAQHFIIVSLSGLIVLVFGVLIGV
FVFYNSKARVFLLPVVNFLYTIPSLALFALFIPLIGVGLKNALLVLVLYGLLPIVHSTYNALKEVREEVIKAAIGLGCNP
KELFFRVRFLLAIPQILVGLRIAVVMLVAMAGIGALIGAGGLGQAIFRGLNTQNTTLLVAGSFIIAVFSVLADKFVSVFQ
HENALQHLLSQNATKKQKRRVYVSVAVFLFLLLASILWLVPRSVIEEKPLVVAAKPSSEQYILGEILSLLLEKHHIPVKR
VFGIGGGTMNIHPALIRGDFDLYVEYTGTAWVNTLKNPLTQKVDFETIKRRYEKEFNLLWVGLLGFNNTYSLAISKEDAQ
KYAVETFSDLAFHSPNFDFGAEFDFFEREDAFKGLVKAYRFHFRSLHEMDINLRYKSFESHKINALDVFTTDAQIKELDL
KVLRDDKGFFPNYQAGIVIRKEIVKKYPKVLEILEKIKISDEKMQDLNYQVEVLKKSPQIVAKDFLENMGL

Sequences:

>Translated_551_residues
MLIMGVFKQLIKELYEWLIHSVDVAIQHLVAMVLKISVVKYLIKEFHDRFIYFIDLIAQHFIIVSLSGLIVLVFGVLIGV
FVFYNSKARVFLLPVVNFLYTIPSLALFALFIPLIGVGLKNALLVLVLYGLLPIVHSTYNALKEVREEVIKAAIGLGCNP
KELFFRVRFLLAIPQILVGLRIAVVMLVAMAGIGALIGAGGLGQAIFRGLNTQNTTLLVAGSFIIAVFSVLADKFVSVFQ
HENALQHLLSQNATKKQKRRVYVSVAVFLFLLLASILWLVPRSVIEEKPLVVAAKPSSEQYILGEILSLLLEKHHIPVKR
VFGIGGGTMNIHPALIRGDFDLYVEYTGTAWVNTLKNPLTQKVDFETIKRRYEKEFNLLWVGLLGFNNTYSLAISKEDAQ
KYAVETFSDLAFHSPNFDFGAEFDFFEREDAFKGLVKAYRFHFRSLHEMDINLRYKSFESHKINALDVFTTDAQIKELDL
KVLRDDKGFFPNYQAGIVIRKEIVKKYPKVLEILEKIKISDEKMQDLNYQVEVLKKSPQIVAKDFLENMGL
>Mature_551_residues
MLIMGVFKQLIKELYEWLIHSVDVAIQHLVAMVLKISVVKYLIKEFHDRFIYFIDLIAQHFIIVSLSGLIVLVFGVLIGV
FVFYNSKARVFLLPVVNFLYTIPSLALFALFIPLIGVGLKNALLVLVLYGLLPIVHSTYNALKEVREEVIKAAIGLGCNP
KELFFRVRFLLAIPQILVGLRIAVVMLVAMAGIGALIGAGGLGQAIFRGLNTQNTTLLVAGSFIIAVFSVLADKFVSVFQ
HENALQHLLSQNATKKQKRRVYVSVAVFLFLLLASILWLVPRSVIEEKPLVVAAKPSSEQYILGEILSLLLEKHHIPVKR
VFGIGGGTMNIHPALIRGDFDLYVEYTGTAWVNTLKNPLTQKVDFETIKRRYEKEFNLLWVGLLGFNNTYSLAISKEDAQ
KYAVETFSDLAFHSPNFDFGAEFDFFEREDAFKGLVKAYRFHFRSLHEMDINLRYKSFESHKINALDVFTTDAQIKELDL
KVLRDDKGFFPNYQAGIVIRKEIVKKYPKVLEILEKIKISDEKMQDLNYQVEVLKKSPQIVAKDFLENMGL

Specific function: Member of a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine, and choline [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788451, Length=239, Percent_Identity=33.0543933054393, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788452, Length=285, Percent_Identity=26.3157894736842, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788449, Length=203, Percent_Identity=31.0344827586207, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789033, Length=200, Percent_Identity=23.5, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 62480; Mature: 62480

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCC
>Mature Secondary Structure
MLIMGVFKQLIKELYEWLIHSVDVAIQHLVAMVLKISVVKYLIKEFHDRFIYFIDLIAQH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIIVSLSGLIVLVFGVLIGVFVFYNSKARVFLLPVVNFLYTIPSLALFALFIPLIGVGLK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NALLVLVLYGLLPIVHSTYNALKEVREEVIKAAIGLGCNPKELFFRVRFLLAIPQILVGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RIAVVMLVAMAGIGALIGAGGLGQAIFRGLNTQNTTLLVAGSFIIAVFSVLADKFVSVFQ
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
HENALQHLLSQNATKKQKRRVYVSVAVFLFLLLASILWLVPRSVIEEKPLVVAAKPSSEQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEECCCCCC
YILGEILSLLLEKHHIPVKRVFGIGGGTMNIHPALIRGDFDLYVEYTGTAWVNTLKNPLT
CHHHHHHHHHHHHCCCCHHHHHCCCCCCCEECCEEEECCEEEEEEECCHHHHHHHHHHHH
QKVDFETIKRRYEKEFNLLWVGLLGFNNTYSLAISKEDAQKYAVETFSDLAFHSPNFDFG
HCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCC
AEFDFFEREDAFKGLVKAYRFHFRSLHEMDINLRYKSFESHKINALDVFTTDAQIKELDL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCHHHHHHH
KVLRDDKGFFPNYQAGIVIRKEIVKKYPKVLEILEKIKISDEKMQDLNYQVEVLKKSPQI
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHCCHHH
VAKDFLENMGL
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]