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The map label for this gene is dcd

Identifier: 109947092

GI number: 109947092

Start: 435972

End: 436538

Strand: Reverse

Name: dcd

Synonym: Hac_0495

Alternate gene names: 109947092

Gene position: 436538-435972 (Counterclockwise)

Preceding gene: 109947098

Following gene: 109947091

Centisome position: 28.09

GC content: 39.15

Gene sequence:

>567_bases
ATGGGATTGAAAGCGGATTCTTGGATTAAAAAAATGAGTTTAGAGCATGGTATGATTAGTCCCTTTTGCGAAAAACAAGT
CGGTAAGAATGTGATTAGCTATGGTTTGAGCAGTTATGGGTATGATATTAGAGTGGGGGGTGAGTTCATGCTCTTTGATA
ATAAAAACGCTTTAATTGACCCTAAAAACTTTGATCCTAACAACGCGACTAAAATTGATGCGTGTAAAGAGGGTTATTTT
ATCTTACCGGCTAATGCGTTCGCCCTAGCCCATACGATAGAGTATTTTAAAATGCCTAAAGACACTTTAGCGATTTGTTT
AGGGAAAAGCACTTACGCTAGGTGTGGGATTATTGTGAATGTCACGCCTTTTGAGCCAGAATTTGAAGGCTATATCACTA
TTGAAATTTCTAACACCACCAATTTACCCGCTAAAGTCTATGCGAATGAAGGGATTGCGCAAGTGGTGTTTTTACAAGGC
GATGAAGTGTGCGAGCAAAGTTATAAAGACAGAGGCGGTAAGTATCAAGGGCAAGTGGGTATCACTTTACCTAAGATTCT
GAAGTAA

Upstream 100 bases:

>100_bases
ATACGCCACAAACACATAATCTTATAGCTATAAGCGTTTTTAGCAAAAAATTATTGTTATAATAACATAATTATTAACAA
ACTTTAAAGGCTTTATGCAT

Downstream 100 bases:

>100_bases
GGAAAAAGTAGAGTTTAAAAGATTCAAATACAAGAAAAAATCAGCATTAGGTTTTGTCGTTTTATAGTAAAATTTTTTCA
TGCAAACCTTGTTTAAAGAA

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MGLKADSWIKKMSLEHGMISPFCEKQVGKNVISYGLSSYGYDIRVGGEFMLFDNKNALIDPKNFDPNNATKIDACKEGYF
ILPANAFALAHTIEYFKMPKDTLAICLGKSTYARCGIIVNVTPFEPEFEGYITIEISNTTNLPAKVYANEGIAQVVFLQG
DEVCEQSYKDRGGKYQGQVGITLPKILK

Sequences:

>Translated_188_residues
MGLKADSWIKKMSLEHGMISPFCEKQVGKNVISYGLSSYGYDIRVGGEFMLFDNKNALIDPKNFDPNNATKIDACKEGYF
ILPANAFALAHTIEYFKMPKDTLAICLGKSTYARCGIIVNVTPFEPEFEGYITIEISNTTNLPAKVYANEGIAQVVFLQG
DEVCEQSYKDRGGKYQGQVGITLPKILK
>Mature_187_residues
GLKADSWIKKMSLEHGMISPFCEKQVGKNVISYGLSSYGYDIRVGGEFMLFDNKNALIDPKNFDPNNATKIDACKEGYFI
LPANAFALAHTIEYFKMPKDTLAICLGKSTYARCGIIVNVTPFEPEFEGYITIEISNTTNLPAKVYANEGIAQVVFLQGD
EVCEQSYKDRGGKYQGQVGITLPKILK

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_HELAH (Q17YF5)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664320.1
- ProteinModelPortal:   Q17YF5
- SMR:   Q17YF5
- STRING:   Q17YF5
- GeneID:   4176407
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0495
- NMPDR:   fig|382638.8.peg.484
- eggNOG:   COG0717
- HOGENOM:   HBG553199
- OMA:   MEYFRIP
- ProtClustDB:   PRK00416
- BioCyc:   HACI382638:HAC_0495-MONOMER
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 20858; Mature: 20727

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLKADSWIKKMSLEHGMISPFCEKQVGKNVISYGLSSYGYDIRVGGEFMLFDNKNALID
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECCCCEEC
PKNFDPNNATKIDACKEGYFILPANAFALAHTIEYFKMPKDTLAICLGKSTYARCGIIVN
CCCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHCCCHHEEEEECCCCHHHCEEEEE
VTPFEPEFEGYITIEISNTTNLPAKVYANEGIAQVVFLQGDEVCEQSYKDRGGKYQGQVG
ECCCCCCCCCEEEEEECCCCCCCEEEEECCCEEEEEEECCHHHHHHHHHHCCCEECCEEC
ITLPKILK
CCCHHHCC
>Mature Secondary Structure 
GLKADSWIKKMSLEHGMISPFCEKQVGKNVISYGLSSYGYDIRVGGEFMLFDNKNALID
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECCCCEEC
PKNFDPNNATKIDACKEGYFILPANAFALAHTIEYFKMPKDTLAICLGKSTYARCGIIVN
CCCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHCCCHHEEEEECCCCHHHCEEEEE
VTPFEPEFEGYITIEISNTTNLPAKVYANEGIAQVVFLQGDEVCEQSYKDRGGKYQGQVG
ECCCCCCCCCEEEEEECCCCCCCEEEEECCCEEEEEEECCHHHHHHHHHHCCCEECCEEC
ITLPKILK
CCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA