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The map label for this gene is efp

Identifier: 109946967

GI number: 109946967

Start: 303775

End: 304338

Strand: Direct

Name: efp

Synonym: Hac_0358

Alternate gene names: 109946967

Gene position: 303775-304338 (Clockwise)

Preceding gene: 109946966

Following gene: 109946968

Centisome position: 19.55

GC content: 42.38

Gene sequence:

>564_bases
ATGGCAATTGGGATGAGTGAGCTCAAAAAGGGCTTAAAAATTGAATTAGGCGGTGTGCCTTATAGGATCGTAGAATACCA
ACATGTCAAGCCCGGTAAGGGTGCGGCTTTTGTGCGCGCGAAAATCAAGTCGTTTTTAGATGGTAAAGTGATTGAGAAAA
CTTTCCATGCGGGGGATAAGTGCGAAGAGCCTAACCTTGTGGAAAAAACGATGCAATACCTTTATCATGATGGCGATGCG
TATCAATTCATGGATATAGAGAGCTATGAGCAAATCGCCTTAAGCGACTCTCAAGTAGGCGAGGCTTCTAAATGGATGTT
GGATGGTATGCAAGTGCAAGTTTTATTGTATAATGACAAGGCGATTTCAGTAGATGTGCCTCAAGTTGTGGCTTTAAAGA
TTGTAGAAACGGCCCCTAATTTTAAGGGCGATACTTCAAGTGCGAGCAAAAAACCAGCGACTTTAGAGACCGGTGCGGTT
GTGCAAGTGCCTTTCCATGTTTTAGAGGGTGAGATTATTAAGGTTAATACCGAAACAGAAGAGTATCTTGAAAAAGTGAA
ATAG

Upstream 100 bases:

>100_bases
TTTCGCTCCGGCCCAATTAGCGCTTAAAAATGTGGTCAAAGGGCGCATGAAACTTTTGGGTAGCTCTAATAAAATTTAAT
TAACAGGGAAAGAGTGTAAC

Downstream 100 bases:

>100_bases
TTTTTCATTGGGTATGGATAAAATACTCAAAAGCATTTTTAAAATCTAGCATGAAAGAGCTTGATTTTAAGCAAGCGATA
ATCTTCTAAAAAGCGATCTT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MAIGMSELKKGLKIELGGVPYRIVEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDKCEEPNLVEKTMQYLYHDGDA
YQFMDIESYEQIALSDSQVGEASKWMLDGMQVQVLLYNDKAISVDVPQVVALKIVETAPNFKGDTSSASKKPATLETGAV
VQVPFHVLEGEIIKVNTETEEYLEKVK

Sequences:

>Translated_187_residues
MAIGMSELKKGLKIELGGVPYRIVEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDKCEEPNLVEKTMQYLYHDGDA
YQFMDIESYEQIALSDSQVGEASKWMLDGMQVQVLLYNDKAISVDVPQVVALKIVETAPNFKGDTSSASKKPATLETGAV
VQVPFHVLEGEIIKVNTETEEYLEKVK
>Mature_186_residues
AIGMSELKKGLKIELGGVPYRIVEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDKCEEPNLVEKTMQYLYHDGDAY
QFMDIESYEQIALSDSQVGEASKWMLDGMQVQVLLYNDKAISVDVPQVVALKIVETAPNFKGDTSSASKKPATLETGAVV
QVPFHVLEGEIIKVNTETEEYLEKVK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=45.0549450549451, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI87082061, Length=184, Percent_Identity=31.5217391304348, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_HELAH (Q17YT0)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664195.1
- ProteinModelPortal:   Q17YT0
- SMR:   Q17YT0
- STRING:   Q17YT0
- GeneID:   4176393
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0358
- NMPDR:   fig|382638.8.peg.346
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q17YT0
- ProtClustDB:   PRK00529
- BioCyc:   HACI382638:HAC_0358-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20757; Mature: 20626

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGMSELKKGLKIELGGVPYRIVEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDK
CCCCHHHHCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCC
CEEPNLVEKTMQYLYHDGDAYQFMDIESYEQIALSDSQVGEASKWMLDGMQVQVLLYNDK
CCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCHHHHEECCEEEEEEEECCC
AISVDVPQVVALKIVETAPNFKGDTSSASKKPATLETGAVVQVPFHVLEGEIIKVNTETE
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEECCCCEEEEEHHHHCCEEEEEECCHH
EYLEKVK
HHHHHCC
>Mature Secondary Structure 
AIGMSELKKGLKIELGGVPYRIVEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDK
CCCHHHHCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCC
CEEPNLVEKTMQYLYHDGDAYQFMDIESYEQIALSDSQVGEASKWMLDGMQVQVLLYNDK
CCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCHHHHEECCEEEEEEEECCC
AISVDVPQVVALKIVETAPNFKGDTSSASKKPATLETGAVVQVPFHVLEGEIIKVNTETE
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEECCCCEEEEEHHHHCCEEEEEECCHH
EYLEKVK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA