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The map label for this gene is ompR [H]

Identifier: 109946957

GI number: 109946957

Start: 295187

End: 295864

Strand: Reverse

Name: ompR [H]

Synonym: Hac_0347

Alternate gene names: 109946957

Gene position: 295864-295187 (Counterclockwise)

Preceding gene: 109946958

Following gene: 109946956

Centisome position: 19.04

GC content: 40.27

Gene sequence:

>678_bases
ATGATAGAAGTTTTGATGATTGAAGATGATATAGAATTGGCTGAATTTTTGAGCGAATTTTTATCCCAACATGGCATCCA
TGTCACCAATTACGATGAACCCTATACCGGCATTAGTGCAGCCAACACGCAGCATTACGATTTGTTGTTGTTGGATTTGA
CTTTGCCTAATTTGGATGGGCTTGAAGTGTGCAGACGCATTTCCAAGCAAAAACACATCCCCATTATCATTTCTTCAGCA
AGAAGCGATGTGGAAGACAAGATTAAAGCACTAGATTATGGGGCGGATGATTACCTCCCTAAACCCTATGATCCTAAAGA
ATTGTTAGCTCGTATCCAGTCTTTACTCAGGCGCTCCCATAAAAAAGAAGAAGTGAGTGAGCCTAGCGAAACGCATATGT
TTAGGATAGATAAAGACAGCCGAGAAGTGTATATGCATGAAAAAAAGCTAGACTTAACTAAGGCTGAATACGAAATCCTT
TCGCTTCTCATCAGCAAAAAAGGTTATGTGTTTAGCCGTGAAAGCATTGCGATTGAGAGCGAGAGCATCAACCCTGAAAG
CTCCAATAAAAGCATTGATGTGATCATTGGCCGTTTGCGATCCAAAATTGAAAAAAACCCCAAACAGCCAGAGCATATCA
TTTCGGTTAGGGGGATTGGCTATAAATTAGAATATTGA

Upstream 100 bases:

>100_bases
ACTCTTTGCTAATGAAATTAGATTTTTAAAAATCGTTTAAAAATCGTTTAAAAATCGTTTAAAAATCGTTTAAAAATCGT
TTAAGGAGTTACCAAGATCA

Downstream 100 bases:

>100_bases
TTCTAATAAGGAGCTAAAGGATTTTGCGTTTTTCTATCTTTTTTAAAGTTTTCGTTTTGTTTACGATAACGCTCTTTAGT
TTTGGGGCGTTCGCTTACTA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MIEVLMIEDDIELAEFLSEFLSQHGIHVTNYDEPYTGISAANTQHYDLLLLDLTLPNLDGLEVCRRISKQKHIPIIISSA
RSDVEDKIKALDYGADDYLPKPYDPKELLARIQSLLRRSHKKEEVSEPSETHMFRIDKDSREVYMHEKKLDLTKAEYEIL
SLLISKKGYVFSRESIAIESESINPESSNKSIDVIIGRLRSKIEKNPKQPEHIISVRGIGYKLEY

Sequences:

>Translated_225_residues
MIEVLMIEDDIELAEFLSEFLSQHGIHVTNYDEPYTGISAANTQHYDLLLLDLTLPNLDGLEVCRRISKQKHIPIIISSA
RSDVEDKIKALDYGADDYLPKPYDPKELLARIQSLLRRSHKKEEVSEPSETHMFRIDKDSREVYMHEKKLDLTKAEYEIL
SLLISKKGYVFSRESIAIESESINPESSNKSIDVIIGRLRSKIEKNPKQPEHIISVRGIGYKLEY
>Mature_225_residues
MIEVLMIEDDIELAEFLSEFLSQHGIHVTNYDEPYTGISAANTQHYDLLLLDLTLPNLDGLEVCRRISKQKHIPIIISSA
RSDVEDKIKALDYGADDYLPKPYDPKELLARIQSLLRRSHKKEEVSEPSETHMFRIDKDSREVYMHEKKLDLTKAEYEIL
SLLISKKGYVFSRESIAIESESINPESSNKSIDVIIGRLRSKIEKNPKQPEHIISVRGIGYKLEY

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=33.6283185840708, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=35.7142857142857, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=34.2342342342342, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=34.375, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=33.0316742081448, Blast_Score=123, Evalue=8e-30,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=29.5964125560538, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=29.4117647058824, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=35.8744394618834, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=33.6283185840708, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=30.4932735426009, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=29.9559471365639, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=29.3859649122807, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=29.4871794871795, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=25.1101321585903, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=31.6666666666667, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=123, Percent_Identity=27.6422764227642, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25929; Mature: 25929

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVLMIEDDIELAEFLSEFLSQHGIHVTNYDEPYTGISAANTQHYDLLLLDLTLPNLDG
CEEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCH
LEVCRRISKQKHIPIIISSARSDVEDKIKALDYGADDYLPKPYDPKELLARIQSLLRRSH
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KKEEVSEPSETHMFRIDKDSREVYMHEKKLDLTKAEYEILSLLISKKGYVFSRESIAIES
HHHHHCCCCHHEEEEECCCCHHEEEHHHHCCHHHHHHHHHHHHHHCCCCEEECCCEEEEC
ESINPESSNKSIDVIIGRLRSKIEKNPKQPEHIISVRGIGYKLEY
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEECCCEEECC
>Mature Secondary Structure
MIEVLMIEDDIELAEFLSEFLSQHGIHVTNYDEPYTGISAANTQHYDLLLLDLTLPNLDG
CEEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCH
LEVCRRISKQKHIPIIISSARSDVEDKIKALDYGADDYLPKPYDPKELLARIQSLLRRSH
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KKEEVSEPSETHMFRIDKDSREVYMHEKKLDLTKAEYEILSLLISKKGYVFSRESIAIES
HHHHHCCCCHHEEEEECCCCHHEEEHHHHCCHHHHHHHHHHHHHHCCCCEEECCCEEEEC
ESINPESSNKSIDVIIGRLRSKIEKNPKQPEHIISVRGIGYKLEY
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA