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The map label for this gene is plsC [H]

Identifier: 109946893

GI number: 109946893

Start: 228334

End: 229026

Strand: Reverse

Name: plsC [H]

Synonym: Hac_0277

Alternate gene names: 109946893

Gene position: 229026-228334 (Counterclockwise)

Preceding gene: 109946894

Following gene: 109946892

Centisome position: 14.74

GC content: 39.97

Gene sequence:

>693_bases
TTGAGAGCGATTTATAGGGCTTTAGTGATCGCTATAGGACTAGCTGTTATCATTGTTTTCAATTATTTTAATCGTAAGAA
TAACAACGCGCGCTCCAGCCGTAAAACTTGTGCATGCTTTTTCTCTCTCGCAGGGGTTCATTTAGAAAAAGTAGGCGCCT
TTGATACGGACGCTAAACTCATTGTTTTAAACCACCAAAGCTTATTGGATATTATTTATTTAGAAGCCTACCACCCCAAT
AATATTTGCTGGATCGCTAAAAAAGAGCTTGGCGAAATCCCTTTTTATGGGCATGCCTTAACGGATACGGAAATGATTTT
GATTGACAGAGAGGATAAAAAGGGGATCGCGAGCCTTTTAAAAGCGTGCAAGGAAAAACTAGAGCAAAACCGCCCGTTAG
TGATTTTCCCTGAGGGCACTAGGGGAAAAGGAGGAGAAAAATTCCTCCCTTTCAAGCAAGGGGCTAAAATCATCGCTGAG
AAATTCCAGCTCAAAATCCAGCCGATAGTCTTAATCAATTCCATTAAAATCTTTAATTCCAAGCCCCTAGAAGCCTATAA
GGCTCGCACCCGTTTAGTCATGCTAAAAGGCTATACGCCTGATTTTAATTCGCCCACTTGGTATGAAGAATTAGAAGAAC
GCATGCAAAAAGAGTATTTAAAACACTACCATGAATTAAATGAAGCTTTTTGA

Upstream 100 bases:

>100_bases
AAAATCTTAGGCTCGCATGATGATTATTATAAAGTTCTAACACCGCATGAACAAATAGGATGGGTCAAAAAAAATGAAAT
CAAATAAAAAGTCAAATCGT

Downstream 100 bases:

>100_bases
TTACGCTCCCTTAAGCCTAGCTTGGCGGGAGTTTTTACAAAGCGAATTTAAAAAACCTTATTTTTTAGAAATAGAAAAAC
GCTACTTAGAAGCCCTAAAA

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MRAIYRALVIAIGLAVIIVFNYFNRKNNNARSSRKTCACFFSLAGVHLEKVGAFDTDAKLIVLNHQSLLDIIYLEAYHPN
NICWIAKKELGEIPFYGHALTDTEMILIDREDKKGIASLLKACKEKLEQNRPLVIFPEGTRGKGGEKFLPFKQGAKIIAE
KFQLKIQPIVLINSIKIFNSKPLEAYKARTRLVMLKGYTPDFNSPTWYEELEERMQKEYLKHYHELNEAF

Sequences:

>Translated_230_residues
MRAIYRALVIAIGLAVIIVFNYFNRKNNNARSSRKTCACFFSLAGVHLEKVGAFDTDAKLIVLNHQSLLDIIYLEAYHPN
NICWIAKKELGEIPFYGHALTDTEMILIDREDKKGIASLLKACKEKLEQNRPLVIFPEGTRGKGGEKFLPFKQGAKIIAE
KFQLKIQPIVLINSIKIFNSKPLEAYKARTRLVMLKGYTPDFNSPTWYEELEERMQKEYLKHYHELNEAF
>Mature_230_residues
MRAIYRALVIAIGLAVIIVFNYFNRKNNNARSSRKTCACFFSLAGVHLEKVGAFDTDAKLIVLNHQSLLDIIYLEAYHPN
NICWIAKKELGEIPFYGHALTDTEMILIDREDKKGIASLLKACKEKLEQNRPLVIFPEGTRGKGGEKFLPFKQGAKIIAE
KFQLKIQPIVLINSIKIFNSKPLEAYKARTRLVMLKGYTPDFNSPTWYEELEERMQKEYLKHYHELNEAF

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17564032, Length=195, Percent_Identity=31.7948717948718, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320151, Length=154, Percent_Identity=31.8181818181818, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281364648, Length=168, Percent_Identity=30.952380952381, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24582856, Length=168, Percent_Identity=30.952380952381, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24582854, Length=168, Percent_Identity=30.952380952381, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 26498; Mature: 26498

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIYRALVIAIGLAVIIVFNYFNRKNNNARSSRKTCACFFSLAGVHLEKVGAFDTDAKL
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
IVLNHQSLLDIIYLEAYHPNNICWIAKKELGEIPFYGHALTDTEMILIDREDKKGIASLL
EEEECHHHEEEEEEEEECCCCEEEEEHHHCCCCCCCCCEECCCEEEEEECCCCHHHHHHH
KACKEKLEQNRPLVIFPEGTRGKGGEKFLPFKQGAKIIAEKFQLKIQPIVLINSIKIFNS
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEEEEEEECCC
KPLEAYKARTRLVMLKGYTPDFNSPTWYEELEERMQKEYLKHYHELNEAF
CCHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRAIYRALVIAIGLAVIIVFNYFNRKNNNARSSRKTCACFFSLAGVHLEKVGAFDTDAKL
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
IVLNHQSLLDIIYLEAYHPNNICWIAKKELGEIPFYGHALTDTEMILIDREDKKGIASLL
EEEECHHHEEEEEEEEECCCCEEEEEHHHCCCCCCCCCEECCCEEEEEECCCCHHHHHHH
KACKEKLEQNRPLVIFPEGTRGKGGEKFLPFKQGAKIIAEKFQLKIQPIVLINSIKIFNS
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEEEEEEECCC
KPLEAYKARTRLVMLKGYTPDFNSPTWYEELEERMQKEYLKHYHELNEAF
CCHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]