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The map label for this gene is fabZ [H]

Identifier: 109946695

GI number: 109946695

Start: 60812

End: 61288

Strand: Direct

Name: fabZ [H]

Synonym: Hac_0062

Alternate gene names: 109946695

Gene position: 60812-61288 (Clockwise)

Preceding gene: 109946694

Following gene: 109946696

Centisome position: 3.91

GC content: 41.93

Gene sequence:

>477_bases
ATGGAAACAAGCCAAAACCCACAATCTCAATTTTTTATAGAGCATATCTTACAGATTTTACCGCACCGCTATCCCATGTT
ATTAGTGGATAGAGTCGTGGAGTTAGAAGCCAATAAAAAAATTGTCGCCTATAAGAATATCACTTTCAATGAAGATGTGT
TTAATGGGCATTTCCCCAATAAGCCCATTTTCCCAGGCGTTTTAATCGTAGAGGGCATGGCACAGAGCGGAGGGCTTTTA
GCTTTCACTAGCTTGTGGGGGTTTGACCCTGAAATGGCGAAAACAAAAATCGTGTATTTCATGACTATTGATAAGGTTAA
ATTCCGTATTCCTGTAACCCCAGGCGATAAATTAGAATACCATTTAGAAGTCCTCAAACATAAGGGTATGATTTGGCAAG
TGGGTGGCACGGCTCAAGTGGATGGCAAGGTGGTCGCTGAAGCCGAATTGAAAGCCATGATCGCAGAGAGAGATTGA

Upstream 100 bases:

>100_bases
TTTGCAAAAGCGAGCGGTTTTCTTGTGGTATAATAGCAGTTATTTTTTAAAATAGCAGGTGCTAAAATCATTAGTTTAAT
CAAAAAGGAGTTGGTATTCC

Downstream 100 bases:

>100_bases
AAATGAGTAAAATTGCAAAAACGGCTATCATTTCTCCTAAAGCAGAGGTTGGTAAGGGCGTAGAAATTGGGGAATTTTGC
GTGATTGGGGATGGTATCAA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
METSQNPQSQFFIEHILQILPHRYPMLLVDRVVELEANKKIVAYKNITFNEDVFNGHFPNKPIFPGVLIVEGMAQSGGLL
AFTSLWGFDPEMAKTKIVYFMTIDKVKFRIPVTPGDKLEYHLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAERD

Sequences:

>Translated_158_residues
METSQNPQSQFFIEHILQILPHRYPMLLVDRVVELEANKKIVAYKNITFNEDVFNGHFPNKPIFPGVLIVEGMAQSGGLL
AFTSLWGFDPEMAKTKIVYFMTIDKVKFRIPVTPGDKLEYHLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAERD
>Mature_158_residues
METSQNPQSQFFIEHILQILPHRYPMLLVDRVVELEANKKIVAYKNITFNEDVFNGHFPNKPIFPGVLIVEGMAQSGGLL
AFTSLWGFDPEMAKTKIVYFMTIDKVKFRIPVTPGDKLEYHLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAERD

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=138, Percent_Identity=47.8260869565217, Blast_Score=134, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17931; Mature: 17931

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METSQNPQSQFFIEHILQILPHRYPMLLVDRVVELEANKKIVAYKNITFNEDVFNGHFPN
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCEECCCCCCCCCCC
KPIFPGVLIVEGMAQSGGLLAFTSLWGFDPEMAKTKIVYFMTIDKVKFRIPVTPGDKLEY
CCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEEEEEECCCCCCHHH
HLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAERD
HHHHHHHCCEEEEECCCEEECCEEEEHHHHHHHHCCCC
>Mature Secondary Structure
METSQNPQSQFFIEHILQILPHRYPMLLVDRVVELEANKKIVAYKNITFNEDVFNGHFPN
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCEECCCCCCCCCCC
KPIFPGVLIVEGMAQSGGLLAFTSLWGFDPEMAKTKIVYFMTIDKVKFRIPVTPGDKLEY
CCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEEEEEECCCCCCHHH
HLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAERD
HHHHHHHCCEEEEECCCEEECCEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA