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The map label for this gene is pgl

Identifier: 108813012

GI number: 108813012

Start: 3210347

End: 3211351

Strand: Reverse

Name: pgl

Synonym: YPN_2852

Alternate gene names: 108813012

Gene position: 3211351-3210347 (Counterclockwise)

Preceding gene: 108813014

Following gene: 108813010

Centisome position: 70.82

GC content: 51.84

Gene sequence:

>1005_bases
ATGAAGCAAGCGGTTTACGTGGCAAGTCCAGACAGCCAACAAATTCATGTCTGGCAATTAGATTCAGCCGGTGAATTAAC
CTTATTGCAAACCGTGGACGTGCCGGGTCAGGTACAGCCGATGGCAATAAGCCCTAATCAGCGCCATCTGTATGTCGGGG
TTCGTCCTGATTTTGGTATTGTCAGCTATCACATTGCCGATGATGGTACGCTGACCGCCGCAGGTATGGCACCGCTTCCC
GGCAGCCCGACTCACATTGACACCGATCGACAAGGTCGCTTCTTGTTCTCTGCTTCTTACAGTTTCAATTGCGTCAGTAT
TAGCCCTATTGATACGCATGGCGTAGTGCAAGCGCCCATTCAGCAATTGGATGACCTGCCCGCGCCACATTCGGCGAATA
TTGACCCAACCAACCAGATCTTGCTGGTTCCTTGCCTGAAAGAGGATAAGGTACGGCTGTTTGATTTGAGCGCGGAGGGG
CAGTTAACCCCCCATGCACAGGCTGATATTACTGTTGCCGCCGGCGCTGGCCCACGTCATATGGCTTTCCACCCGAATCA
TCAGGTTGCTTATTGTGTTAACGAACTCAATAGCTCGGTGGATGTGTATCAAATCAGCAATAACGGTCAGGAATACCACT
TAGTGCAGAGCCTGGACGCGATGCCTGCCGATTTCACCGGGACACGTTGGGCGGCGGATATTCATATCACGCCTAATGGC
CGCTATTTATACATCAGTGACCGTACCGCCAACCTGTTGGGTATTTTCACCGTTTCTGAAGATGGCCGGGTGATTTCGTT
GGTCGGGCACCACCTGACCGAAGCCCAACCGCGTGGTTTCAATATCGACCACAGTGGTAATTTCCTGATTGCTTCCGGTC
AGAAATCTGATCATATCGAAGTTTATCGTATCGATCAGAACACGGGGGAGCTAACCACCCTGAAACGTTATCCGGTAGGT
AAGGGGCCGATGTGGGTCAGTATCCGGGGGGCGCAGAACTCATAA

Upstream 100 bases:

>100_bases
AATTAACCGTTAATAAAAGATATTTGGTTAAGGCGAAGGGGCTGGAACAGGTCAATTCACCTTAATAGCGTTACCCAACA
GGTTCGACTAAGGAGTAAAG

Downstream 100 bases:

>100_bases
ACAATAGGCCATTTTACTGACTATTTTGAACCTGGGCAGTGCGGTCACCCTGATGTACGCTTGAGTGACTGTGCACTGCC
CATGTCTAAATTGACGGCGA

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6-P-gluconolactonase

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKQAVYVASPDSQQIHVWQLDSAGELTLLQTVDVPGQVQPMAISPNQRHLYVGVRPDFGIVSYHIADDGTLTAAGMAPLP
GSPTHIDTDRQGRFLFSASYSFNCVSISPIDTHGVVQAPIQQLDDLPAPHSANIDPTNQILLVPCLKEDKVRLFDLSAEG
QLTPHAQADITVAAGAGPRHMAFHPNHQVAYCVNELNSSVDVYQISNNGQEYHLVQSLDAMPADFTGTRWAADIHITPNG
RYLYISDRTANLLGIFTVSEDGRVISLVGHHLTEAQPRGFNIDHSGNFLIASGQKSDHIEVYRIDQNTGELTTLKRYPVG
KGPMWVSIRGAQNS

Sequences:

>Translated_334_residues
MKQAVYVASPDSQQIHVWQLDSAGELTLLQTVDVPGQVQPMAISPNQRHLYVGVRPDFGIVSYHIADDGTLTAAGMAPLP
GSPTHIDTDRQGRFLFSASYSFNCVSISPIDTHGVVQAPIQQLDDLPAPHSANIDPTNQILLVPCLKEDKVRLFDLSAEG
QLTPHAQADITVAAGAGPRHMAFHPNHQVAYCVNELNSSVDVYQISNNGQEYHLVQSLDAMPADFTGTRWAADIHITPNG
RYLYISDRTANLLGIFTVSEDGRVISLVGHHLTEAQPRGFNIDHSGNFLIASGQKSDHIEVYRIDQNTGELTTLKRYPVG
KGPMWVSIRGAQNS
>Mature_334_residues
MKQAVYVASPDSQQIHVWQLDSAGELTLLQTVDVPGQVQPMAISPNQRHLYVGVRPDFGIVSYHIADDGTLTAAGMAPLP
GSPTHIDTDRQGRFLFSASYSFNCVSISPIDTHGVVQAPIQQLDDLPAPHSANIDPTNQILLVPCLKEDKVRLFDLSAEG
QLTPHAQADITVAAGAGPRHMAFHPNHQVAYCVNELNSSVDVYQISNNGQEYHLVQSLDAMPADFTGTRWAADIHITPNG
RYLYISDRTANLLGIFTVSEDGRVISLVGHHLTEAQPRGFNIDHSGNFLIASGQKSDHIEVYRIDQNTGELTTLKRYPVG
KGPMWVSIRGAQNS

Specific function: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate

COG id: COG2706

COG function: function code G; 3-carboxymuconate cyclase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cycloisomerase 2 family

Homologues:

Organism=Escherichia coli, GI1786983, Length=329, Percent_Identity=56.838905775076, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 6PGL_YERP3 (A7FKN1)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001401809.1
- ProteinModelPortal:   A7FKN1
- SMR:   A7FKN1
- STRING:   A7FKN1
- GeneID:   5387500
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_2846
- eggNOG:   COG2706
- HOGENOM:   HBG741123
- OMA:   LKEDRIR
- ProtClustDB:   PRK11028
- BioCyc:   YPSE349747:YPSIP31758_2846-MONOMER
- HAMAP:   MF_01605
- InterPro:   IPR022528
- InterPro:   IPR019405
- InterPro:   IPR011045
- InterPro:   IPR015943
- Gene3D:   G3DSA:2.130.10.10

Pfam domain/function: PF10282 DUF2394; SSF50974 N2O_reductase_N

EC number: =3.1.1.31

Molecular weight: Translated: 36446; Mature: 36446

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQAVYVASPDSQQIHVWQLDSAGELTLLQTVDVPGQVQPMAISPNQRHLYVGVRPDFGI
CCCEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCE
VSYHIADDGTLTAAGMAPLPGSPTHIDTDRQGRFLFSASYSFNCVSISPIDTHGVVQAPI
EEEEEECCCEEEECCCCCCCCCCCEECCCCCCCEEEEECCEEEEEEECCCCCCCCCHHHH
QQLDDLPAPHSANIDPTNQILLVPCLKEDKVRLFDLSAEGQLTPHAQADITVAAGAGPRH
HHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCC
MAFHPNHQVAYCVNELNSSVDVYQISNNGQEYHLVQSLDAMPADFTGTRWAADIHITPNG
EEECCCCCEEEEEHHHCCCEEEEEECCCCCEEEEEEHHCCCCCCCCCCEEEEEEEECCCC
RYLYISDRTANLLGIFTVSEDGRVISLVGHHLTEAQPRGFNIDHSGNFLIASGQKSDHIE
CEEEEECCCCEEEEEEEECCCCCEEEEECCHHCCCCCCCEECCCCCCEEEECCCCCCCEE
VYRIDQNTGELTTLKRYPVGKGPMWVSIRGAQNS
EEEEECCCCCEEEEEECCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MKQAVYVASPDSQQIHVWQLDSAGELTLLQTVDVPGQVQPMAISPNQRHLYVGVRPDFGI
CCCEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCE
VSYHIADDGTLTAAGMAPLPGSPTHIDTDRQGRFLFSASYSFNCVSISPIDTHGVVQAPI
EEEEEECCCEEEECCCCCCCCCCCEECCCCCCCEEEEECCEEEEEEECCCCCCCCCHHHH
QQLDDLPAPHSANIDPTNQILLVPCLKEDKVRLFDLSAEGQLTPHAQADITVAAGAGPRH
HHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCC
MAFHPNHQVAYCVNELNSSVDVYQISNNGQEYHLVQSLDAMPADFTGTRWAADIHITPNG
EEECCCCCEEEEEHHHCCCEEEEEECCCCCEEEEEEHHCCCCCCCCCCEEEEEEEECCCC
RYLYISDRTANLLGIFTVSEDGRVISLVGHHLTEAQPRGFNIDHSGNFLIASGQKSDHIE
CEEEEECCCCEEEEEEEECCCCCEEEEECCHHCCCCCCCEECCCCCCEEEECCCCCCCEE
VYRIDQNTGELTTLKRYPVGKGPMWVSIRGAQNS
EEEEECCCCCEEEEEECCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA