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The map label for this gene is betT [H]

Identifier: 108812993

GI number: 108812993

Start: 3188725

End: 3190773

Strand: Reverse

Name: betT [H]

Synonym: YPN_2833

Alternate gene names: 108812993

Gene position: 3190773-3188725 (Counterclockwise)

Preceding gene: 108812997

Following gene: 108812992

Centisome position: 70.37

GC content: 49.44

Gene sequence:

>2049_bases
ATGGTGACTTCAGACATCGACACAAAACCGCAAAAGGATACGTTAAATCCGGTGGTGTTCTTTACGTCCGCGGGGTTGAT
CCTCGCGTTCTGTCTTATGACTATTTTTTATACTGACCTCTCTAATCGCTGGATTGGTATTACCCTTAACTGGGTCTCTG
CCACTTTTGGTTGGTACTATCTGCTGGCGGCCACGCTGTATATCGTTTTTGTTATTTATATTGCCACTTCACGCTATGGC
TCAATCAAACTTGGCCCCGAGCAGTCAAAGCCCGAGTTCAGCCTGGTCAGTTGGGCGGCAATGCTGTTCGCCGCCGGTAT
CGGTATTGACCTGATGTTCTTCTCGGTAGCCGAACCCGTGACGCAATATATGATGCCACCAGAAGGCCAGGGCCAGACTC
TGGAAGCCGCGCGGCAGGCGATGGTCTGGACGCTGTTCCACTATGGGCTGACAGGTTGGTCAATGTATGCATTGATGGGG
ATTGCACTCGGTTACTTCAGCTATCGCTATAACCTGCCGTTGACCATCCGTTCCGCGCTTTACCCTATCTTTGGTAAGCG
GATCGACGGGCCAATCGGCCACAGTGTGGATATCGCCGCCGTTATCGGGACGATTTTCGGGATTGCCACCACATTGGGGA
TTGGGGTGGTGCAGCTCAATTACGGCCTCAATGTCCTGTTTCATATCCCGGAAAGTCTGGCGGTTCAGGCCGGGTTAATT
CTGTTGTCGGTGGTGATGGCGGCAGTATCGGTGACATCGGGTGTCAACAAAGGCATTCGGATCCTCTCTGAAGTGAATGT
TCTGCTGGCGTTAGGCCTGATCCTATTCCTGCTGTTCTGGGGGAACACGGAATTCCTGCTGAATGCGCTGGTGCTTAACG
TGGGGGATTATATCAATCGCTTTTTGGGCATGACGCTCAACAGTTTTGCTTTTGATCGCCCAACCCAATGGATGAATAGC
TGGACGCTGTTTTTCTGGGCATGGTGGGTTGCCTGGTCACCCTTTGTTGGTCTGTTTCTGGCGCGTATTTCCCGTGGCCG
CACTATCCGCCAATTTGTGGTCGGTACGTTGATCATACCCTTTGTCTTCACCTTGCTTTGGCTGTCTATCTTCGGTAATA
GCGCGTTGTACCAGATCCTGCATGGCAATATTGCTTTTGCTAATGAAGTGATGGAGTTTCCGGAACGCGGTTTCTATAGC
CTGTTAGCACAGTACCCCGGTTTCACTTTGAGTGCTTCGGTTGCCACGATCACCGGCTTGCTATTTTATGTCACGTCAGC
GGATTCCGGTTCGCTAGTGCTGGGGAATTTCACCTCTCGTCTGGCCGATATTAATAATGATTCCCCCAACTGGTTACGTA
CTTTCTGGTCTATTACTATCGGGTTACTGACTTTGGGAATGTTGATGACCGATGGTGTCGCCGCCTTGCAAAACGCAACC
GTCATTATGGGGTTACCGTTCAGTTTTGTGATTTTCTTCGTGATGGTCGGCTTGTATAAATCGCTAAAAATTGAGGATTA
CCGCAAAGCCAGCTCGCAACAGACACCAACGCCTACGCTGATTTCAGGCAATGAAGTACTAAATTGGAAACAACGTTTAT
CGCGAGTAATGAACTACCCAGGTACCACTTATACCGCGAAAATACTGGATACCATTTGCCGCCCAGCGATGGAGGAAGTT
GCGCAGGAACTGGCCGTACGCGGTGTTAAAGTTGAATTCAACGAACTGCCGCCGAAGGAAGATGAACAACTGAATCGTCT
TAATCATCTGGAGTTGCTGGTACATCTGGGTGATGAGCAGAACTTCGTCTACCAGATCTGGCCGCAACGTTATTCTGTGC
CGGCATTCACCTACCGTGCACGCTCAGGGAAATCACACTATTACCGCCTTGAAACTTATCTGCTTGAAGGAACGCAGGGG
AATGATTTGATGGACTACAGCAAAGAACAGATTATCAATAACATTCTTGACCAGTATGAGCGCCATATGAACTTCCTACA
TATTCAAAGTGAAGCGCCGGGAAATATCATGACATTTCCCGATCAATAA

Upstream 100 bases:

>100_bases
ACTCAGCGGATCGCCTGCGAGCAGTCTCTTGATATGCGCTAAGGGGCGCTTACCCACCAAATGTGATGAGCCTTACTTTT
TTAAAAATGCAGGGGAAACG

Downstream 100 bases:

>100_bases
TCCGCAATAGTGGGGTCTCTTCATCTGGCGAGTCGATGAAGAGATCACCACCGCTTAATCAAAATCATCTGCCGCTTTTT
CTGGCTTAACTTTATTAATG

Product: choline transport protein BetT

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MVTSDIDTKPQKDTLNPVVFFTSAGLILAFCLMTIFYTDLSNRWIGITLNWVSATFGWYYLLAATLYIVFVIYIATSRYG
SIKLGPEQSKPEFSLVSWAAMLFAAGIGIDLMFFSVAEPVTQYMMPPEGQGQTLEAARQAMVWTLFHYGLTGWSMYALMG
IALGYFSYRYNLPLTIRSALYPIFGKRIDGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLNVLFHIPESLAVQAGLI
LLSVVMAAVSVTSGVNKGIRILSEVNVLLALGLILFLLFWGNTEFLLNALVLNVGDYINRFLGMTLNSFAFDRPTQWMNS
WTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVVGTLIIPFVFTLLWLSIFGNSALYQILHGNIAFANEVMEFPERGFYS
LLAQYPGFTLSASVATITGLLFYVTSADSGSLVLGNFTSRLADINNDSPNWLRTFWSITIGLLTLGMLMTDGVAALQNAT
VIMGLPFSFVIFFVMVGLYKSLKIEDYRKASSQQTPTPTLISGNEVLNWKQRLSRVMNYPGTTYTAKILDTICRPAMEEV
AQELAVRGVKVEFNELPPKEDEQLNRLNHLELLVHLGDEQNFVYQIWPQRYSVPAFTYRARSGKSHYYRLETYLLEGTQG
NDLMDYSKEQIINNILDQYERHMNFLHIQSEAPGNIMTFPDQ

Sequences:

>Translated_682_residues
MVTSDIDTKPQKDTLNPVVFFTSAGLILAFCLMTIFYTDLSNRWIGITLNWVSATFGWYYLLAATLYIVFVIYIATSRYG
SIKLGPEQSKPEFSLVSWAAMLFAAGIGIDLMFFSVAEPVTQYMMPPEGQGQTLEAARQAMVWTLFHYGLTGWSMYALMG
IALGYFSYRYNLPLTIRSALYPIFGKRIDGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLNVLFHIPESLAVQAGLI
LLSVVMAAVSVTSGVNKGIRILSEVNVLLALGLILFLLFWGNTEFLLNALVLNVGDYINRFLGMTLNSFAFDRPTQWMNS
WTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVVGTLIIPFVFTLLWLSIFGNSALYQILHGNIAFANEVMEFPERGFYS
LLAQYPGFTLSASVATITGLLFYVTSADSGSLVLGNFTSRLADINNDSPNWLRTFWSITIGLLTLGMLMTDGVAALQNAT
VIMGLPFSFVIFFVMVGLYKSLKIEDYRKASSQQTPTPTLISGNEVLNWKQRLSRVMNYPGTTYTAKILDTICRPAMEEV
AQELAVRGVKVEFNELPPKEDEQLNRLNHLELLVHLGDEQNFVYQIWPQRYSVPAFTYRARSGKSHYYRLETYLLEGTQG
NDLMDYSKEQIINNILDQYERHMNFLHIQSEAPGNIMTFPDQ
>Mature_682_residues
MVTSDIDTKPQKDTLNPVVFFTSAGLILAFCLMTIFYTDLSNRWIGITLNWVSATFGWYYLLAATLYIVFVIYIATSRYG
SIKLGPEQSKPEFSLVSWAAMLFAAGIGIDLMFFSVAEPVTQYMMPPEGQGQTLEAARQAMVWTLFHYGLTGWSMYALMG
IALGYFSYRYNLPLTIRSALYPIFGKRIDGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLNVLFHIPESLAVQAGLI
LLSVVMAAVSVTSGVNKGIRILSEVNVLLALGLILFLLFWGNTEFLLNALVLNVGDYINRFLGMTLNSFAFDRPTQWMNS
WTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVVGTLIIPFVFTLLWLSIFGNSALYQILHGNIAFANEVMEFPERGFYS
LLAQYPGFTLSASVATITGLLFYVTSADSGSLVLGNFTSRLADINNDSPNWLRTFWSITIGLLTLGMLMTDGVAALQNAT
VIMGLPFSFVIFFVMVGLYKSLKIEDYRKASSQQTPTPTLISGNEVLNWKQRLSRVMNYPGTTYTAKILDTICRPAMEEV
AQELAVRGVKVEFNELPPKEDEQLNRLNHLELLVHLGDEQNFVYQIWPQRYSVPAFTYRARSGKSHYYRLETYLLEGTQG
NDLMDYSKEQIINNILDQYERHMNFLHIQSEAPGNIMTFPDQ

Specific function: High-affinity uptake of choline driven by a proton- motive force [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=678, Percent_Identity=78.3185840707965, Blast_Score=1117, Evalue=0.0,
Organism=Escherichia coli, GI1788102, Length=457, Percent_Identity=29.7592997811816, Blast_Score=188, Evalue=9e-49,
Organism=Escherichia coli, GI1786224, Length=506, Percent_Identity=27.0750988142292, Blast_Score=169, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 76676; Mature: 76676

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTSDIDTKPQKDTLNPVVFFTSAGLILAFCLMTIFYTDLSNRWIGITLNWVSATFGWYY
CCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
LLAATLYIVFVIYIATSRYGSIKLGPEQSKPEFSLVSWAAMLFAAGIGIDLMFFSVAEPV
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TQYMMPPEGQGQTLEAARQAMVWTLFHYGLTGWSMYALMGIALGYFSYRYNLPLTIRSAL
HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCEEHHHHH
YPIFGKRIDGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLNVLFHIPESLAVQAGLI
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECCHHHHHHHHHH
LLSVVMAAVSVTSGVNKGIRILSEVNVLLALGLILFLLFWGNTEFLLNALVLNVGDYINR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FLGMTLNSFAFDRPTQWMNSWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVVGTLIIP
HHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FVFTLLWLSIFGNSALYQILHGNIAFANEVMEFPERGFYSLLAQYPGFTLSASVATITGL
HHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEHHHHHHHHH
LFYVTSADSGSLVLGNFTSRLADINNDSPNWLRTFWSITIGLLTLGMLMTDGVAALQNAT
HHEEEECCCCCEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCE
VIMGLPFSFVIFFVMVGLYKSLKIEDYRKASSQQTPTPTLISGNEVLNWKQRLSRVMNYP
EEEECCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHCCC
GTTYTAKILDTICRPAMEEVAQELAVRGVKVEFNELPPKEDEQLNRLNHLELLVHLGDEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHEEEECCCC
NFVYQIWPQRYSVPAFTYRARSGKSHYYRLETYLLEGTQGNDLMDYSKEQIINNILDQYE
CEEEEECCCCCCCCCEEEECCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
RHMNFLHIQSEAPGNIMTFPDQ
HHCCEEEEECCCCCCEEECCCC
>Mature Secondary Structure
MVTSDIDTKPQKDTLNPVVFFTSAGLILAFCLMTIFYTDLSNRWIGITLNWVSATFGWYY
CCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
LLAATLYIVFVIYIATSRYGSIKLGPEQSKPEFSLVSWAAMLFAAGIGIDLMFFSVAEPV
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TQYMMPPEGQGQTLEAARQAMVWTLFHYGLTGWSMYALMGIALGYFSYRYNLPLTIRSAL
HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCEEHHHHH
YPIFGKRIDGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLNVLFHIPESLAVQAGLI
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECCHHHHHHHHHH
LLSVVMAAVSVTSGVNKGIRILSEVNVLLALGLILFLLFWGNTEFLLNALVLNVGDYINR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FLGMTLNSFAFDRPTQWMNSWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVVGTLIIP
HHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FVFTLLWLSIFGNSALYQILHGNIAFANEVMEFPERGFYSLLAQYPGFTLSASVATITGL
HHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEHHHHHHHHH
LFYVTSADSGSLVLGNFTSRLADINNDSPNWLRTFWSITIGLLTLGMLMTDGVAALQNAT
HHEEEECCCCCEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCE
VIMGLPFSFVIFFVMVGLYKSLKIEDYRKASSQQTPTPTLISGNEVLNWKQRLSRVMNYP
EEEECCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHCCC
GTTYTAKILDTICRPAMEEVAQELAVRGVKVEFNELPPKEDEQLNRLNHLELLVHLGDEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHEEEECCCC
NFVYQIWPQRYSVPAFTYRARSGKSHYYRLETYLLEGTQGNDLMDYSKEQIINNILDQYE
CEEEEECCCCCCCCCEEEECCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
RHMNFLHIQSEAPGNIMTFPDQ
HHCCEEEEECCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]