Click here to switch to the map view.

The map label for this gene is glvR [H]

Identifier: 108812883

GI number: 108812883

Start: 3072496

End: 3073236

Strand: Reverse

Name: glvR [H]

Synonym: YPN_2723

Alternate gene names: 108812883

Gene position: 3073236-3072496 (Counterclockwise)

Preceding gene: 108812884

Following gene: 108812882

Centisome position: 67.77

GC content: 37.65

Gene sequence:

>741_bases
ATGTTTACTTATAAAGAAATATCGACGCTGAACGAATTGGAATTGATAGTTTATAATTACATCATAAAAAATACTGACAA
AGTGATGTACATGACGATCAGGGAGCTCGCAGATGCCTCGGGTGTTTCTACCACCACGGTTTTACGATTTTGTAAAAAAA
TGAACTGTGATGGTTATTCTGAATTCCGTATCCGGTTTAAATTATATTTAGAACATGATGAGAAACCACCAGTTACCTTT
GGCATCAGTGAAATAATCAGTTATTTTAAGAGCATTAATAATAGCGAGTTTGATGAGCTATTAGATAACGTAGCGAAACA
GATAGCGGCAACGCGCAGAGTTATTTTTGTTGGTATAGGTACCTCGGGAGCATTGGGGAAATACAGCGCCCGCTTCTTTT
CTAATGTTGGTAAATACAGTACCTACATTGATGATCCCTATTATCCTATTAACAGCGACATGTATCAGGACGCGGTCGCC
ATTATCCTTTCAGTCTCTGGAGAAACAGAAGAAATTATTCGCATTGCCAACCAATTTAGCCTGCAAAATTGTAAAATTAT
CAGCCTGACCAACAGTGAAAGTTCCACCTTGGCTAAAATGGCTGATCTCAATATCTCCTATCACATGCCCCCGGTTATCC
TTGAAGGCCAGTATAATATTACTACCCAAATTCCGGTGCTATATATTATTGAAACTATTGGCAAGAAATTACCTCAGCTA
ATGAATAAAAACACCAAATAA

Upstream 100 bases:

>100_bases
AACTGGCTCGTCCATGGCCCCATTTCATGCTACATTCGCGTGTCTTGGGCCATTGCAAGCGCCCTAAAGGCAGGTCGCTA
ACGGGAATTCAGGTATCAAT

Downstream 100 bases:

>100_bases
AACAGGGTGTTTTTCACATGTAACATATTACAAACGGTACATTTTGTTATATCGTGACTTCGCTTTTCTTTTTGCTAGAA
TCCCTCCTCGATATCCTGTA

Product: LacI-family regulatory protein

Products: NA

Alternate protein names: Glv operon regulatory protein [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MFTYKEISTLNELELIVYNYIIKNTDKVMYMTIRELADASGVSTTTVLRFCKKMNCDGYSEFRIRFKLYLEHDEKPPVTF
GISEIISYFKSINNSEFDELLDNVAKQIAATRRVIFVGIGTSGALGKYSARFFSNVGKYSTYIDDPYYPINSDMYQDAVA
IILSVSGETEEIIRIANQFSLQNCKIISLTNSESSTLAKMADLNISYHMPPVILEGQYNITTQIPVLYIIETIGKKLPQL
MNKNTK

Sequences:

>Translated_246_residues
MFTYKEISTLNELELIVYNYIIKNTDKVMYMTIRELADASGVSTTTVLRFCKKMNCDGYSEFRIRFKLYLEHDEKPPVTF
GISEIISYFKSINNSEFDELLDNVAKQIAATRRVIFVGIGTSGALGKYSARFFSNVGKYSTYIDDPYYPINSDMYQDAVA
IILSVSGETEEIIRIANQFSLQNCKIISLTNSESSTLAKMADLNISYHMPPVILEGQYNITTQIPVLYIIETIGKKLPQL
MNKNTK
>Mature_246_residues
MFTYKEISTLNELELIVYNYIIKNTDKVMYMTIRELADASGVSTTTVLRFCKKMNCDGYSEFRIRFKLYLEHDEKPPVTF
GISEIISYFKSINNSEFDELLDNVAKQIAATRRVIFVGIGTSGALGKYSARFFSNVGKYSTYIDDPYYPINSDMYQDAVA
IILSVSGETEEIIRIANQFSLQNCKIISLTNSESSTLAKMADLNISYHMPPVILEGQYNITTQIPVLYIIETIGKKLPQL
MNKNTK

Specific function: Positive regulator of the glv operon expression, which consists of glvA, glvR and glvC [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 27991; Mature: 27991

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00356 HTH_LACI_1 ; PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTYKEISTLNELELIVYNYIIKNTDKVMYMTIRELADASGVSTTTVLRFCKKMNCDGYS
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
EFRIRFKLYLEHDEKPPVTFGISEIISYFKSINNSEFDELLDNVAKQIAATRRVIFVGIG
EEEEEEEEEEECCCCCCEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCEEEEEEEC
TSGALGKYSARFFSNVGKYSTYIDDPYYPINSDMYQDAVAIILSVSGETEEIIRIANQFS
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHEEEECCCCHHHHHHHHHHHC
LQNCKIISLTNSESSTLAKMADLNISYHMPPVILEGQYNITTQIPVLYIIETIGKKLPQL
CCCEEEEEEECCCHHHHHHHHHCCEEECCCCEEEECCCCEEECCHHHHHHHHHHHHHHHH
MNKNTK
HCCCCC
>Mature Secondary Structure
MFTYKEISTLNELELIVYNYIIKNTDKVMYMTIRELADASGVSTTTVLRFCKKMNCDGYS
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
EFRIRFKLYLEHDEKPPVTFGISEIISYFKSINNSEFDELLDNVAKQIAATRRVIFVGIG
EEEEEEEEEEECCCCCCEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCEEEEEEEC
TSGALGKYSARFFSNVGKYSTYIDDPYYPINSDMYQDAVAIILSVSGETEEIIRIANQFS
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHEEEECCCCHHHHHHHHHHHC
LQNCKIISLTNSESSTLAKMADLNISYHMPPVILEGQYNITTQIPVLYIIETIGKKLPQL
CCCEEEEEEECCCHHHHHHHHHCCEEECCCCEEEECCCCEEECCHHHHHHHHHHHHHHHH
MNKNTK
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 11489864 [H]