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The map label for this gene is ycgM [C]

Identifier: 108812574

GI number: 108812574

Start: 2697940

End: 2698782

Strand: Reverse

Name: ycgM [C]

Synonym: YPN_2413

Alternate gene names: 108812574

Gene position: 2698782-2697940 (Counterclockwise)

Preceding gene: 108812575

Following gene: 108812573

Centisome position: 59.52

GC content: 51.72

Gene sequence:

>843_bases
ATGAAACTATTACGTTATGGTCCCGTCGGCGAGGAGCGCCCGGCGTTACTTGATGAGTTGGGAGAGATTCGTGATCTCTC
GGCACATATCGAGGATATCAGTGGCAAATTTTTACTGCCTGCGACGCTGTACAAACTGCGTCAGTTGGATAGCGCCAGTT
TGCCCCTCGTTCGGGGTGAACAACGCCTTGGTGCTTGCGTGGGTCATGTCGGTAAGTTTATCTGTGTTGGTCTGAACTAC
GCCGATCATGCTGCTGAAACGGGGGCAGAAATCCCGCAAGAACCGGTGATCTTCAATAAGTGGACCAGCGCCATTATTGG
TCCGAATGACGATATAGAAATCCCGCGTAACTCAGTGAAAACCGATTGGGAAGTTGAACTGGGGGTGGTGATTGGCACAG
GCGGGCGATATATCGGTGAGGCCAACGCCATGTCTTACGTTGCTGGCTATTGCGTGGTCAACGATATTTCCGAACGTGAG
TTCCAGCTAGAGCATGGCGGTACCTGGGATAAAGGGAAGGGTTGCGATACCTTCGGGCCGATTGGACCGTGGTTAGTGAC
CCGCGATGAAATACCCGATCCACATCAGCTAGGGTTGTGGTTAGACGTTGATGGCAGGCGCTATCAGAACGGCAGTACCC
GCACCATGATTTTCAAAATCCCGCAAATAATCAGTTATCTAAGCCGCTTTATGAGTTTGCAATCCGGGGATGTCATTTCT
ACCGGTACCCCACCTGGCGTGGGTCTTGGGCAAAAACCGCCCGTCTATTTACATGCAGGGCAGATAATGCGTTTGGGTAT
CGAAGGTCTGGGAGAACAGTGCCAGAAAACGATACAAGCGTAG

Upstream 100 bases:

>100_bases
GCGCTTACACCACCGGCACGATACATATTATCGACGGAGGCTGGAGCAATTAATACTTAGCGACTGTCATGGGTATTCAG
TCAGTTCTGAGGAGAACGAC

Downstream 100 bases:

>100_bases
TACTCATCTTTCGCGAACGGAGAGGTTAACCATGACAATAATCACTGCATTACGCACTGAGGATGTACGTTTTCCCACCT
CGTTGGAATTGGATGGTTCG

Product: hydrolase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGEQRLGACVGHVGKFICVGLNY
ADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVKTDWEVELGVVIGTGGRYIGEANAMSYVAGYCVVNDISERE
FQLEHGGTWDKGKGCDTFGPIGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVIS
TGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA

Sequences:

>Translated_280_residues
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGEQRLGACVGHVGKFICVGLNY
ADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVKTDWEVELGVVIGTGGRYIGEANAMSYVAGYCVVNDISERE
FQLEHGGTWDKGKGCDTFGPIGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVIS
TGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA
>Mature_280_residues
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGEQRLGACVGHVGKFICVGLNY
ADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVKTDWEVELGVVIGTGGRYIGEANAMSYVAGYCVVNDISERE
FQLEHGGTWDKGKGCDTFGPIGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVIS
TGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=240, Percent_Identity=44.5833333333333, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI40786394, Length=240, Percent_Identity=43.3333333333333, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI66348062, Length=179, Percent_Identity=43.0167597765363, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI215422413, Length=179, Percent_Identity=43.0167597765363, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI13654274, Length=179, Percent_Identity=43.0167597765363, Blast_Score=143, Evalue=2e-34,
Organism=Escherichia coli, GI1787428, Length=182, Percent_Identity=38.4615384615385, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17557057, Length=199, Percent_Identity=37.6884422110553, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6324161, Length=216, Percent_Identity=30.0925925925926, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28572127, Length=209, Percent_Identity=44.4976076555024, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28571789, Length=204, Percent_Identity=38.7254901960784, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24663695, Length=210, Percent_Identity=35.7142857142857, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30644; Mature: 30644

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGE
CCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCEECH
QRLGACVGHVGKFICVGLNYADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVK
HHHHHHHHHHHHEEEEECCCHHHHHHHCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCC
TDWEVELGVVIGTGGRYIGEANAMSYVAGYCVVNDISEREFQLEHGGTWDKGKGCDTFGP
CCEEEEEEEEEECCCCEECCCHHHHHHHHHHEEECCCCCEEEECCCCCCCCCCCCCCCCC
IGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVIS
CCCEEEECCCCCCHHHEEEEEECCCCEECCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEE
TGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA
CCCCCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGE
CCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCEECH
QRLGACVGHVGKFICVGLNYADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVK
HHHHHHHHHHHHEEEEECCCHHHHHHHCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCC
TDWEVELGVVIGTGGRYIGEANAMSYVAGYCVVNDISEREFQLEHGGTWDKGKGCDTFGP
CCEEEEEEEEEECCCCEECCCHHHHHHHHHHEEECCCCCEEEECCCCCCCCCCCCCCCCC
IGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVIS
CCCEEEECCCCCCHHHEEEEEECCCCEECCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEE
TGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA
CCCCCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA