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The map label for this gene is infC [H]

Identifier: 108812049

GI number: 108812049

Start: 2131102

End: 2131452

Strand: Reverse

Name: infC [H]

Synonym: YPN_1887

Alternate gene names: 108812049

Gene position: 2131452-2131102 (Counterclockwise)

Preceding gene: 108812050

Following gene: 108812048

Centisome position: 47.0

GC content: 47.58

Gene sequence:

>351_bases
ATGGATTACGGCAAATTCCTCTACGAGAAGAGCAAGTCGACAAAAGAACAGAAGAAGAAGCAAAAAGTCATTCAGGTTAA
GGAAATTAAATTCCGTCCTGGTACCGATGATGGCGACTATCAGGTCAAACTACGCAACCTGATTCGCTTTCTGGAAGATG
GCGATAAAGCCAAAATCACCCTGCGGTTCCGTGGGCGTGAAATGGCGCACCAACAGATCGGTATGGAAGTGCTTAACCGC
GTCCGTAAAGATCTGTGTGAAGATTCTGATTTGGCCGTTGTCGAGTCCTTCCCGACTCGTATCGAAGGCCGTCAGATGAT
CATGGTGCTCGCACCTAAGAAGAGACAGTAA

Upstream 100 bases:

>100_bases
TGGTATTGTCAGTCTGAATGAAGCTCTTGAAAAAGCCGAGGAAGCTGGTGTTGATTTAGTAGAAATCAGTCCGAATGCCG
AGCCGCCAGTTTGTCGTATA

Downstream 100 bases:

>100_bases
GGCATTCAAGTAGCAGGTTTCTCTACGCTTGCGTAGTAAGAAACCTGTTCGCCTAGCTAGCTCGTTGTAATTAACAATGC
GAAGTGGATATATTCAATGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQQIGMEVLNR
VRKDLCEDSDLAVVESFPTRIEGRQMIMVLAPKKRQ

Sequences:

>Translated_116_residues
MDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQQIGMEVLNR
VRKDLCEDSDLAVVESFPTRIEGRQMIMVLAPKKRQ
>Mature_116_residues
MDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQQIGMEVLNR
VRKDLCEDSDLAVVESFPTRIEGRQMIMVLAPKKRQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=116, Percent_Identity=89.6551724137931, Blast_Score=180, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 13691; Mature: 13691

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKIT
CCHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCCCEEHHHHHHHHHCCCCCEEEE
LRFRGREMAHQQIGMEVLNRVRKDLCEDSDLAVVESFPTRIEGRQMIMVLAPKKRQ
EEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKIT
CCHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCCCEEHHHHHHHHHCCCCCEEEE
LRFRGREMAHQQIGMEVLNRVRKDLCEDSDLAVVESFPTRIEGRQMIMVLAPKKRQ
EEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8405963 [H]