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The map label for this gene is btuR [H]

Identifier: 108811843

GI number: 108811843

Start: 1896296

End: 1896940

Strand: Reverse

Name: btuR [H]

Synonym: YPN_1681

Alternate gene names: 108811843

Gene position: 1896940-1896296 (Counterclockwise)

Preceding gene: 108811844

Following gene: 108811839

Centisome position: 41.83

GC content: 49.61

Gene sequence:

>645_bases
ATGCACAGCCCGGCCGTAAACCTGGTCCAGCTGAATAAAAGGAACGTAATCATTATGTCTGAAGATCGCCACCAGCAGCG
CCAACAACGATTAAAAGAAAAGGTAGATTCACGGATTGCTGCAGCACAGGAAGTTCGCGGTATTTTGATCGTGTTTACCG
GTAACGGGAAAGGTAAAACCACAGCAGCTTTCGGAACAGTCACCCGCGCGGTGGGCCATGGCCTTAAAGCGGGAGTCATA
CAGTTTATCAAGGGGGAGTGGCCAAACGGTGAAAAGAACCTGCTGCAACAACATGGCGTTGAATTTCAGGTGATGGCGAC
CGGTTTTACCTGGAATACACAAGACAGGGAGACGGATACGGTAGCCTGTCTGGGGGTTTGGCAACATGCTTTACGCATGT
TAGCAGACCCAACATTGGATTTAGTGGTATTGGATGAGCTGACCTATATGATCGCTTACGACTACTTGCCATTGGATGAG
GTGATTAACGCACTCAATCAGCGCCCTGCTCATCAAACGGTGATTATTACAGGCCGTGGGTGCCACCGGGATCTACTGGA
GATGGCGGATACCGTCAGTGAGTTACGTCCCGTCAAACATGCTTTCGATGCAGGAATAAAAGCGCAGCAAGGTATTGATT
GGTAA

Upstream 100 bases:

>100_bases
GATGAAGATGCGAGCAAGTTGAAAACGCCAGCAGATATTATGCCGTTGTACCTCTATTTGATGGGCGATGACAGCCGTAG
AAAAACGGGGATCAGCTTCG

Downstream 100 bases:

>100_bases
TATTTTATAAGCGTTAAAAATAATATTGCCGCAGTCCAAAAAACTGCGGCAATAAGCATTATTCACGTCGCTATTGATGT
CTAATGACAGACGCGGTTAA

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MHSPAVNLVQLNKRNVIIMSEDRHQQRQQRLKEKVDSRIAAAQEVRGILIVFTGNGKGKTTAAFGTVTRAVGHGLKAGVI
QFIKGEWPNGEKNLLQQHGVEFQVMATGFTWNTQDRETDTVACLGVWQHALRMLADPTLDLVVLDELTYMIAYDYLPLDE
VINALNQRPAHQTVIITGRGCHRDLLEMADTVSELRPVKHAFDAGIKAQQGIDW

Sequences:

>Translated_214_residues
MHSPAVNLVQLNKRNVIIMSEDRHQQRQQRLKEKVDSRIAAAQEVRGILIVFTGNGKGKTTAAFGTVTRAVGHGLKAGVI
QFIKGEWPNGEKNLLQQHGVEFQVMATGFTWNTQDRETDTVACLGVWQHALRMLADPTLDLVVLDELTYMIAYDYLPLDE
VINALNQRPAHQTVIITGRGCHRDLLEMADTVSELRPVKHAFDAGIKAQQGIDW
>Mature_214_residues
MHSPAVNLVQLNKRNVIIMSEDRHQQRQQRLKEKVDSRIAAAQEVRGILIVFTGNGKGKTTAAFGTVTRAVGHGLKAGVI
QFIKGEWPNGEKNLLQQHGVEFQVMATGFTWNTQDRETDTVACLGVWQHALRMLADPTLDLVVLDELTYMIAYDYLPLDE
VINALNQRPAHQTVIITGRGCHRDLLEMADTVSELRPVKHAFDAGIKAQQGIDW

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=79.0816326530612, Blast_Score=339, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 23918; Mature: 23918

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSPAVNLVQLNKRNVIIMSEDRHQQRQQRLKEKVDSRIAAAQEVRGILIVFTGNGKGKT
CCCCCCEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCC
TAAFGTVTRAVGHGLKAGVIQFIKGEWPNGEKNLLQQHGVEFQVMATGFTWNTQDRETDT
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEECEEECCCCCCCHH
VACLGVWQHALRMLADPTLDLVVLDELTYMIAYDYLPLDEVINALNQRPAHQTVIITGRG
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCC
CHRDLLEMADTVSELRPVKHAFDAGIKAQQGIDW
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MHSPAVNLVQLNKRNVIIMSEDRHQQRQQRLKEKVDSRIAAAQEVRGILIVFTGNGKGKT
CCCCCCEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCC
TAAFGTVTRAVGHGLKAGVIQFIKGEWPNGEKNLLQQHGVEFQVMATGFTWNTQDRETDT
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEECEEECCCCCCCHH
VACLGVWQHALRMLADPTLDLVVLDELTYMIAYDYLPLDEVINALNQRPAHQTVIITGRG
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCC
CHRDLLEMADTVSELRPVKHAFDAGIKAQQGIDW
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]