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The map label for this gene is hofB [H]

Identifier: 108810827

GI number: 108810827

Start: 775961

End: 777517

Strand: Reverse

Name: hofB [H]

Synonym: YPN_0662

Alternate gene names: 108810827

Gene position: 777517-775961 (Counterclockwise)

Preceding gene: 108810828

Following gene: 162139448

Centisome position: 17.15

GC content: 45.99

Gene sequence:

>1557_bases
ATGATAAGGCCCCATCAAATGGTTGAATTTATAGTGTCCTCATTTGAAACAATTAGTGATGAATTACACCTTCTCTGTCG
GCGTTATCGGGCAGTGGCACTCACTCTTGATGGTAAAAGCCTTTCGATAGCTTCAGCCCAGACCGTTGATGAAGCGTTAT
TGACCGCGTTGCGTTTCACATGTGGCCGTCAAGTCAGAGTGGAATATTGGCCCGAAGCCAAGATTGAACAATCATTGTAT
TTGGGGAGCCCGACGAAAAATAACCTAAACAGTAGTATTAACAACGGGCTAAATAGCGCGTTGTTATCCCAAAAGGGAGG
TGATCCGTCGCGAGTAAAACCGCACAATCAGCAGCAACAGACAATAGATGATACTGTGTTTGATAATGAGAGTGACACAC
CCGTCATTCAATTCATAACCCAGACGCTAAGTCTAGCCATTCAAAAACGCGCTTCAGATATCCATTTTGAGCCTTATCAA
CACCACTATCGTGTTCGTTTAAGAATTGATGGTGTGTTGCATGAATTCACCCCACCCGAGGCCGAATGGGCAGCTCGGAT
TAGCAGTTGCCTGAAGGTCATGGCGAAATTAAATATTGCTGAACGGCGATTACCACAAGATGGTCAACTAACCTTACCCT
TTGGTGATTCACACTATTCAATGCGGATAGCGACTCTCCCTACGCAATATGGTGAAAAAGTGGTATTGCGTATTCTTCAA
ATACAACAGCAAACCACGTTAGAAAAGCTGGGGATGACGGATGCGGCACTGAAACAATTAACACAGGCATTATCAGCACC
ACAAGGGCTGATTCTGGTCACCGGCCCTACCGGTAGTGGCAAAACCATTACGTTATATTGCAGTTTAGCGCGGCTGAATC
AGACACAAAGAAACATCTGTAGCGTCGAAGATCCTATTGAGATCCCCGTCAATGGCATTAACCAAACCCAGGTAAACAGC
AAGATCGGTCTGGATTTCTCTCGAATACTACGAGCCATCCTACGACAGGACCCTGATGTCATTATGGTTGGTGAAATTCG
TGATAATGAAACCGCCAGTATCGCAGTTAACGCGGCCCAGACCGGGCATTTGGTCCTATCGACGCTGCACACTAACTCAA
CAGCAGAAACGCTGATACGCATGGCACAAATGGGAATAGAACGCCATTTAATCGCCTCAAGTCTAAAACTCGTCATTGCT
CAACGCTTGGTGCGCCGCCTATGTTTACATTGCCGCCAGGCTGCATCTCACCCCTTTATTCCACCAGCTCACATAAGGTC
TGGTCCGATCCAACACTATCTAGCTGTAGGTTGTGAGCATTGTTGTACGGGTTATTATGGCCGAACGGGTATTTATGAAA
TGCTGAGTGTAACGCCGCAGATTCAGCAAGCCATACTCAATAATGCCAGCCCTGTAAAACTGGTACAAATTGCCCAGAAG
CAAGAACAAACAGCCTTACTCTGCTCAGGTTTAGCTTTAATCGAAAAAGGCATCACTACCCTTAGTGAAATTAATCGTGT
TGTGGGCTTCGTAGCAGAAACAGAGGTCACCTCTTGA

Upstream 100 bases:

>100_bases
TCACCAACCCGAAACAGCAACGGAAATTTAGTCTGGGCCAGAACATGTACGGCAACAGATAGTGCCATGACTGATAGTTG
TAAAGCGGTATTCCGTTTCA

Downstream 100 bases:

>100_bases
GCCGCCATCGTTTATTCAATTGGACAGCTCTCAACAAAACAGGGGAGCTACAGACGGGCATGCTACTGGCAACTGAGAGA
AACAGTGTCTATGAACATAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MIRPHQMVEFIVSSFETISDELHLLCRRYRAVALTLDGKSLSIASAQTVDEALLTALRFTCGRQVRVEYWPEAKIEQSLY
LGSPTKNNLNSSINNGLNSALLSQKGGDPSRVKPHNQQQQTIDDTVFDNESDTPVIQFITQTLSLAIQKRASDIHFEPYQ
HHYRVRLRIDGVLHEFTPPEAEWAARISSCLKVMAKLNIAERRLPQDGQLTLPFGDSHYSMRIATLPTQYGEKVVLRILQ
IQQQTTLEKLGMTDAALKQLTQALSAPQGLILVTGPTGSGKTITLYCSLARLNQTQRNICSVEDPIEIPVNGINQTQVNS
KIGLDFSRILRAILRQDPDVIMVGEIRDNETASIAVNAAQTGHLVLSTLHTNSTAETLIRMAQMGIERHLIASSLKLVIA
QRLVRRLCLHCRQAASHPFIPPAHIRSGPIQHYLAVGCEHCCTGYYGRTGIYEMLSVTPQIQQAILNNASPVKLVQIAQK
QEQTALLCSGLALIEKGITTLSEINRVVGFVAETEVTS

Sequences:

>Translated_518_residues
MIRPHQMVEFIVSSFETISDELHLLCRRYRAVALTLDGKSLSIASAQTVDEALLTALRFTCGRQVRVEYWPEAKIEQSLY
LGSPTKNNLNSSINNGLNSALLSQKGGDPSRVKPHNQQQQTIDDTVFDNESDTPVIQFITQTLSLAIQKRASDIHFEPYQ
HHYRVRLRIDGVLHEFTPPEAEWAARISSCLKVMAKLNIAERRLPQDGQLTLPFGDSHYSMRIATLPTQYGEKVVLRILQ
IQQQTTLEKLGMTDAALKQLTQALSAPQGLILVTGPTGSGKTITLYCSLARLNQTQRNICSVEDPIEIPVNGINQTQVNS
KIGLDFSRILRAILRQDPDVIMVGEIRDNETASIAVNAAQTGHLVLSTLHTNSTAETLIRMAQMGIERHLIASSLKLVIA
QRLVRRLCLHCRQAASHPFIPPAHIRSGPIQHYLAVGCEHCCTGYYGRTGIYEMLSVTPQIQQAILNNASPVKLVQIAQK
QEQTALLCSGLALIEKGITTLSEINRVVGFVAETEVTS
>Mature_518_residues
MIRPHQMVEFIVSSFETISDELHLLCRRYRAVALTLDGKSLSIASAQTVDEALLTALRFTCGRQVRVEYWPEAKIEQSLY
LGSPTKNNLNSSINNGLNSALLSQKGGDPSRVKPHNQQQQTIDDTVFDNESDTPVIQFITQTLSLAIQKRASDIHFEPYQ
HHYRVRLRIDGVLHEFTPPEAEWAARISSCLKVMAKLNIAERRLPQDGQLTLPFGDSHYSMRIATLPTQYGEKVVLRILQ
IQQQTTLEKLGMTDAALKQLTQALSAPQGLILVTGPTGSGKTITLYCSLARLNQTQRNICSVEDPIEIPVNGINQTQVNS
KIGLDFSRILRAILRQDPDVIMVGEIRDNETASIAVNAAQTGHLVLSTLHTNSTAETLIRMAQMGIERHLIASSLKLVIA
QRLVRRLCLHCRQAASHPFIPPAHIRSGPIQHYLAVGCEHCCTGYYGRTGIYEMLSVTPQIQQAILNNASPVKLVQIAQK
QEQTALLCSGLALIEKGITTLSEINRVVGFVAETEVTS

Specific function: Unknown

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1786296, Length=491, Percent_Identity=45.213849287169, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1789723, Length=403, Percent_Identity=47.6426799007444, Blast_Score=350, Evalue=1e-97,
Organism=Escherichia coli, GI87082188, Length=278, Percent_Identity=33.4532374100719, Blast_Score=116, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007831
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E; PF05157 GSPII_E_N [H]

EC number: NA

Molecular weight: Translated: 57390; Mature: 57390

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPHQMVEFIVSSFETISDELHLLCRRYRAVALTLDGKSLSIASAQTVDEALLTALRFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEHHHHHHHHHHHHHHHHH
CGRQVRVEYWPEAKIEQSLYLGSPTKNNLNSSINNGLNSALLSQKGGDPSRVKPHNQQQQ
CCCCEEEEECCCCHHCCCEEECCCCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHH
TIDDTVFDNESDTPVIQFITQTLSLAIQKRASDIHFEPYQHHYRVRLRIDGVLHEFTPPE
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECHHHCCCCCH
AEWAARISSCLKVMAKLNIAERRLPQDGQLTLPFGDSHYSMRIATLPTQYGEKVVLRILQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHH
IQQQTTLEKLGMTDAALKQLTQALSAPQGLILVTGPTGSGKTITLYCSLARLNQTQRNIC
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEHHHHCHHHHHHC
SVEDPIEIPVNGINQTQVNSKIGLDFSRILRAILRQDPDVIMVGEIRDNETASIAVNAAQ
CCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCC
TGHLVLSTLHTNSTAETLIRMAQMGIERHLIASSLKLVIAQRLVRRLCLHCRQAASHPFI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PPAHIRSGPIQHYLAVGCEHCCTGYYGRTGIYEMLSVTPQIQQAILNNASPVKLVQIAQK
CCHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHH
QEQTALLCSGLALIEKGITTLSEINRVVGFVAETEVTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIRPHQMVEFIVSSFETISDELHLLCRRYRAVALTLDGKSLSIASAQTVDEALLTALRFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEHHHHHHHHHHHHHHHHH
CGRQVRVEYWPEAKIEQSLYLGSPTKNNLNSSINNGLNSALLSQKGGDPSRVKPHNQQQQ
CCCCEEEEECCCCHHCCCEEECCCCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHH
TIDDTVFDNESDTPVIQFITQTLSLAIQKRASDIHFEPYQHHYRVRLRIDGVLHEFTPPE
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECHHHCCCCCH
AEWAARISSCLKVMAKLNIAERRLPQDGQLTLPFGDSHYSMRIATLPTQYGEKVVLRILQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHH
IQQQTTLEKLGMTDAALKQLTQALSAPQGLILVTGPTGSGKTITLYCSLARLNQTQRNIC
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEHHHHCHHHHHHC
SVEDPIEIPVNGINQTQVNSKIGLDFSRILRAILRQDPDVIMVGEIRDNETASIAVNAAQ
CCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCC
TGHLVLSTLHTNSTAETLIRMAQMGIERHLIASSLKLVIAQRLVRRLCLHCRQAASHPFI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PPAHIRSGPIQHYLAVGCEHCCTGYYGRTGIYEMLSVTPQIQQAILNNASPVKLVQIAQK
CCHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHH
QEQTALLCSGLALIEKGITTLSEINRVVGFVAETEVTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959070; 8202364; 9278503 [H]