| Definition | Yersinia pestis Nepal516, complete genome. |
|---|---|
| Accession | NC_008149 |
| Length | 4,534,590 |
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The map label for this gene is lptD [H]
Identifier: 108810534
GI number: 108810534
Start: 445330
End: 447708
Strand: Reverse
Name: lptD [H]
Synonym: YPN_0369
Alternate gene names: 108810534
Gene position: 447708-445330 (Counterclockwise)
Preceding gene: 108810536
Following gene: 108810533
Centisome position: 9.87
GC content: 47.96
Gene sequence:
>2379_bases ATGATGCCCCCCGATGACGGAACACCAAAACCACGTATGAAAAAAAGATTCCCAACACTGCTGGCCACATTGATTTGGAC GGCACTATATAGTCAACACACACTGGCAGACCTTGCGGAGCAATGTATGCTCGGTGTCCCAACCTATGATCAACCACTGG TCACAGGCGATCCGAATCAACTGCCGGTCCGTATTAATGCGGATAAAACCGAAGCAAACTATCCGGATAATGCCTTGTTT ACTGGCAATGTTATTGTTCAGCAAGGCAATAGCACCCTAACAGCGAACCAAGTGGAACTGACACAGGTACAGAAACCCGG TGAAGTCATTCCCCTTCGTACCGTTACCGCCACCGGCGATGTCAACTACGACGATCCGCAAATCAAGCTGAAAGGACCAA AAGGTTGGTCAAATCTGAACACCAAAGATACTGATATGGACAAAGGTAAATATCAGATGGTGGGCCGTCAGGGCCGTGGT GATGCAGATTTGATGAAATTGCGCGATCAGAGCCGCTACACCATTTTGAAAAACGGCACATTTACCTCTTGCCTACCCGG AGATAACAGTTGGAGCGTGGTTGGCTCAGAGGTCATTCATGACCGCGAAGAACAAGTGGTTGAAGTTTGGAATGCTCGTT TCAAGATTGGCAAAGTCCCGGTGTTTTACAGCCCTTATATGCAATTGCCAGTTGGCGATAAACGCCGTTCGGGGTTCTTG ATCCCAAATGCGAAATTTACCAGTAACAATGGTTTTGAGTTTTTACTCCCTTATTACTGGAATATTGCCCCCAACTTTGA TGCCACCATTACGCCACACTATATGGAAAGGCGCGGGTTGCAATGGCAAAACGAATTCCGCTATTTGCTGGCGCCGGGTT CAGGCACCATGGCATTAGACTGGTTGCCCAATGACCGTATCTATACGGGGCCTGATGGCACAGATAAAAATGCCACCCGC TGGTTATACTACTGGGGCCATTCCGGTGTAATGGATCAAGTTTGGCGCTTCAACATCAACTATACCCGTGTCAGCGACCC CGCTTACTTTACGGATTTAACCTCTCAGTACGGTTCGACAACCGATGGCTACGCGACACAAATATTCACCGCCGGTTATG CCAATGAAAACTGGAATGCGACGCTGTCTTCCAAGCAGTTCCAGGTATTTACTGCTGCAGGTAACAGTAATGCCTACCGT GCCCAGCCACAGTTGGACATGAACTACTACAAAAACGATGTTGGTCCATTTGATATGCATGTCTATGGTCAGGCGGCCAA ATTCACCAGTGTCAATCCAACTAACCCGGAAGCCAGCCGTTTCCATATTGAACCTACGGTTAACCTGCCCTTATCCAATA GCTGGGGAAGCATAAATACAGAAGCCAAACTGTTGGCCACCCACTATCAACAGGATATTCCGGCCAGTTTTGCTGACAAT GCTAGCAACCCCAAACTGAAAGACTCAGTAAACCGGGTCCTACCACAGTTTAAAGTGGATGGTAAGGTGGTATTCGATAG GTCAATGGACTGGGCGACGGGCTTTACGCAGACATTGGAGCCTCGCGCACAGTATCTCTACGTCCCTTACCGGAACCAAG ATGATATCTATATATACGACACCACGTTGATGCAGTCGGATTACTCTGGTCTGTTCCGTGATCGTACCTATAGTGGCTTG GACCGTATTGCATCGGCTAATCAGGTATCTACCGGTTTAACCTCTCGCATATATGATGATGCTCGGGTTGAACGTTTTAA TGTCTCTGTAGGTCAAATCTATTACTTCAGTCGATCACGCACAGGTAATACCGAAGCCATCGATAACAGTAACGCGACAG GAAGCCTGGTTTGGGCTGGTGATACTTTTTGGCGGATCAACGATCAACTGGGCCTGAAGGGCGGTGCACAGTATGATACG CGGCTGGGAAGTTTGACCTTAGGTAACGCTATAATGGAATATAGAAAAGACGCTGATCGTATGATTCAATTGAATTATCG CTACGCGAGCCCAAAATATATTCAGGCTGCTGTCCCTAAAGTATACAACCCTGACTACCAGCAAGGCATCTCTCAGGTAG GTACCACGGCCAGTTGGCCAATTGCTGACCGCTGGGCGATCGTCGGGGCGTATTATTACGATACCAAAGCCAAACAACCT GCCAGCCAGTTAGTTGGCTTGCAATACAACACCTGTTGTTGGGCGGTAAACCTTGGCTATGAACGCAAAATAACTGGCTG GAATGCACAAGGCCAAACCAGTAAGTACGACAACAAAATAGGCTTTAACATCGAATTACGTGGTTTGAGCGGTGGTCATA GCCTTGGTACTGCTCAAATGCTGAACTCGGGCATTCTGCCTTATCAAAGTGCATTCTGA
Upstream 100 bases:
>100_bases TCGGCATTTAGCTCAGCGCCTAACGGCGAGACGTGTAAACGGCCAGATTTAACACTAGCGCAACTGTGATGAGTGATATA GTCTCAAACCGTTTGCCGGC
Downstream 100 bases:
>100_bases TACTGTTTAACACACTGAATACAGTGAATCTTAACCCGCGATAGCGGATTACATAAATGGAAAAGGTATGAAGAACTGGA GAACGCTTATTCTCGGATTG
Product: organic solvent tolerance protein
Products: NA
Alternate protein names: Organic solvent tolerance protein [H]
Number of amino acids: Translated: 792; Mature: 792
Protein sequence:
>792_residues MMPPDDGTPKPRMKKRFPTLLATLIWTALYSQHTLADLAEQCMLGVPTYDQPLVTGDPNQLPVRINADKTEANYPDNALF TGNVIVQQGNSTLTANQVELTQVQKPGEVIPLRTVTATGDVNYDDPQIKLKGPKGWSNLNTKDTDMDKGKYQMVGRQGRG DADLMKLRDQSRYTILKNGTFTSCLPGDNSWSVVGSEVIHDREEQVVEVWNARFKIGKVPVFYSPYMQLPVGDKRRSGFL IPNAKFTSNNGFEFLLPYYWNIAPNFDATITPHYMERRGLQWQNEFRYLLAPGSGTMALDWLPNDRIYTGPDGTDKNATR WLYYWGHSGVMDQVWRFNINYTRVSDPAYFTDLTSQYGSTTDGYATQIFTAGYANENWNATLSSKQFQVFTAAGNSNAYR AQPQLDMNYYKNDVGPFDMHVYGQAAKFTSVNPTNPEASRFHIEPTVNLPLSNSWGSINTEAKLLATHYQQDIPASFADN ASNPKLKDSVNRVLPQFKVDGKVVFDRSMDWATGFTQTLEPRAQYLYVPYRNQDDIYIYDTTLMQSDYSGLFRDRTYSGL DRIASANQVSTGLTSRIYDDARVERFNVSVGQIYYFSRSRTGNTEAIDNSNATGSLVWAGDTFWRINDQLGLKGGAQYDT RLGSLTLGNAIMEYRKDADRMIQLNYRYASPKYIQAAVPKVYNPDYQQGISQVGTTASWPIADRWAIVGAYYYDTKAKQP ASQLVGLQYNTCCWAVNLGYERKITGWNAQGQTSKYDNKIGFNIELRGLSGGHSLGTAQMLNSGILPYQSAF
Sequences:
>Translated_792_residues MMPPDDGTPKPRMKKRFPTLLATLIWTALYSQHTLADLAEQCMLGVPTYDQPLVTGDPNQLPVRINADKTEANYPDNALF TGNVIVQQGNSTLTANQVELTQVQKPGEVIPLRTVTATGDVNYDDPQIKLKGPKGWSNLNTKDTDMDKGKYQMVGRQGRG DADLMKLRDQSRYTILKNGTFTSCLPGDNSWSVVGSEVIHDREEQVVEVWNARFKIGKVPVFYSPYMQLPVGDKRRSGFL IPNAKFTSNNGFEFLLPYYWNIAPNFDATITPHYMERRGLQWQNEFRYLLAPGSGTMALDWLPNDRIYTGPDGTDKNATR WLYYWGHSGVMDQVWRFNINYTRVSDPAYFTDLTSQYGSTTDGYATQIFTAGYANENWNATLSSKQFQVFTAAGNSNAYR AQPQLDMNYYKNDVGPFDMHVYGQAAKFTSVNPTNPEASRFHIEPTVNLPLSNSWGSINTEAKLLATHYQQDIPASFADN ASNPKLKDSVNRVLPQFKVDGKVVFDRSMDWATGFTQTLEPRAQYLYVPYRNQDDIYIYDTTLMQSDYSGLFRDRTYSGL DRIASANQVSTGLTSRIYDDARVERFNVSVGQIYYFSRSRTGNTEAIDNSNATGSLVWAGDTFWRINDQLGLKGGAQYDT RLGSLTLGNAIMEYRKDADRMIQLNYRYASPKYIQAAVPKVYNPDYQQGISQVGTTASWPIADRWAIVGAYYYDTKAKQP ASQLVGLQYNTCCWAVNLGYERKITGWNAQGQTSKYDNKIGFNIELRGLSGGHSLGTAQMLNSGILPYQSAF >Mature_792_residues MMPPDDGTPKPRMKKRFPTLLATLIWTALYSQHTLADLAEQCMLGVPTYDQPLVTGDPNQLPVRINADKTEANYPDNALF TGNVIVQQGNSTLTANQVELTQVQKPGEVIPLRTVTATGDVNYDDPQIKLKGPKGWSNLNTKDTDMDKGKYQMVGRQGRG DADLMKLRDQSRYTILKNGTFTSCLPGDNSWSVVGSEVIHDREEQVVEVWNARFKIGKVPVFYSPYMQLPVGDKRRSGFL IPNAKFTSNNGFEFLLPYYWNIAPNFDATITPHYMERRGLQWQNEFRYLLAPGSGTMALDWLPNDRIYTGPDGTDKNATR WLYYWGHSGVMDQVWRFNINYTRVSDPAYFTDLTSQYGSTTDGYATQIFTAGYANENWNATLSSKQFQVFTAAGNSNAYR AQPQLDMNYYKNDVGPFDMHVYGQAAKFTSVNPTNPEASRFHIEPTVNLPLSNSWGSINTEAKLLATHYQQDIPASFADN ASNPKLKDSVNRVLPQFKVDGKVVFDRSMDWATGFTQTLEPRAQYLYVPYRNQDDIYIYDTTLMQSDYSGLFRDRTYSGL DRIASANQVSTGLTSRIYDDARVERFNVSVGQIYYFSRSRTGNTEAIDNSNATGSLVWAGDTFWRINDQLGLKGGAQYDT RLGSLTLGNAIMEYRKDADRMIQLNYRYASPKYIQAAVPKVYNPDYQQGISQVGTTASWPIADRWAIVGAYYYDTKAKQP ASQLVGLQYNTCCWAVNLGYERKITGWNAQGQTSKYDNKIGFNIELRGLSGGHSLGTAQMLNSGILPYQSAF
Specific function: Together with lptE, is involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]
COG id: COG1452
COG function: function code M; Organic solvent tolerance protein OstA
Gene ontology:
Cell location: Cell outer membrane [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the lptD family [H]
Homologues:
Organism=Escherichia coli, GI1786239, Length=786, Percent_Identity=66.5394402035623, Blast_Score=1103, Evalue=0.0,
Paralogues:
None
Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020889 - InterPro: IPR005653 - InterPro: IPR007543 [H]
Pfam domain/function: PF03968 OstA; PF04453 OstA_C [H]
EC number: NA
Molecular weight: Translated: 89234; Mature: 89234
Theoretical pI: Translated: 7.56; Mature: 7.56
Prosite motif: PS00435 PEROXIDASE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMPPDDGTPKPRMKKRFPTLLATLIWTALYSQHTLADLAEQCMLGVPTYDQPLVTGDPNQ CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEECCCCCE LPVRINADKTEANYPDNALFTGNVIVQQGNSTLTANQVELTQVQKPGEVIPLRTVTATGD EEEEEECCCCCCCCCCCEEEECEEEEECCCCEEEECEEEEEEECCCCCEEEEEEEEECCC VNYDDPQIKLKGPKGWSNLNTKDTDMDKGKYQMVGRQGRGDADLMKLRDQSRYTILKNGT CCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHCCCCCEEEEECCC FTSCLPGDNSWSVVGSEVIHDREEQVVEVWNARFKIGKVPVFYSPYMQLPVGDKRRSGFL EEEECCCCCCCEEECHHHHHCHHHHHHHHHCCEEEECCCEEEECCEEECCCCCCCCCCEE IPNAKFTSNNGFEFLLPYYWNIAPNFDATITPHYMERRGLQWQNEFRYLLAPGSGTMALD CCCCEECCCCCCEEEEEEEEECCCCCCCEECCHHHHHCCCCCCCCCEEEEECCCCCEEEE WLPNDRIYTGPDGTDKNATRWLYYWGHSGVMDQVWRFNINYTRVSDPAYFTDLTSQYGST ECCCCCEEECCCCCCCCCEEEEEEECCCCHHHHHEEEEEEEEEECCCHHHHHHHHHHCCC TDGYATQIFTAGYANENWNATLSSKQFQVFTAAGNSNAYRAQPQLDMNYYKNDVGPFDMH CCCCEEEEEEECCCCCCCCEEECCCEEEEEEEECCCCCEECCCCCCHHHHHCCCCCEEEE VYGQAAKFTSVNPTNPEASRFHIEPTVNLPLSNSWGSINTEAKLLATHYQQDIPASFADN EEECCEEECCCCCCCCCCCEEEECEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCC ASNPKLKDSVNRVLPQFKVDGKVVFDRSMDWATGFTQTLEPRAQYLYVPYRNQDDIYIYD CCCCCHHHHHHHHCCCEECCCEEEEECCCCCCCCCHHHCCCCCCEEEEEECCCCCEEEEE TTLMQSDYSGLFRDRTYSGLDRIASANQVSTGLTSRIYDDARVERFNVSVGQIYYFSRSR EEEECCCCCHHHHCCCHHHHHHHHCCCHHHHCHHHHHHCCCCEEEEECEEEEEEEEECCC TGNTEAIDNSNATGSLVWAGDTFWRINDQLGLKGGAQYDTRLGSLTLGNAIMEYRKDADR CCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCHHCCCCCEEHHHHHHHHHCCCCE MIQLNYRYASPKYIQAAVPKVYNPDYQQGISQVGTTASWPIADRWAIVGAYYYDTKAKQP EEEEEEEECCCCHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCC ASQLVGLQYNTCCWAVNLGYERKITGWNAQGQTSKYDNKIGFNIELRGLSGGHSLGTAQM HHHHCCCEECCEEEEEECCCEEEECCCCCCCCCCCCCCEECEEEEEEECCCCCCCCHHHH LNSGILPYQSAF HHCCCCCCCCCC >Mature Secondary Structure MMPPDDGTPKPRMKKRFPTLLATLIWTALYSQHTLADLAEQCMLGVPTYDQPLVTGDPNQ CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEECCCCCE LPVRINADKTEANYPDNALFTGNVIVQQGNSTLTANQVELTQVQKPGEVIPLRTVTATGD EEEEEECCCCCCCCCCCEEEECEEEEECCCCEEEECEEEEEEECCCCCEEEEEEEEECCC VNYDDPQIKLKGPKGWSNLNTKDTDMDKGKYQMVGRQGRGDADLMKLRDQSRYTILKNGT CCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHCCCCCEEEEECCC FTSCLPGDNSWSVVGSEVIHDREEQVVEVWNARFKIGKVPVFYSPYMQLPVGDKRRSGFL EEEECCCCCCCEEECHHHHHCHHHHHHHHHCCEEEECCCEEEECCEEECCCCCCCCCCEE IPNAKFTSNNGFEFLLPYYWNIAPNFDATITPHYMERRGLQWQNEFRYLLAPGSGTMALD CCCCEECCCCCCEEEEEEEEECCCCCCCEECCHHHHHCCCCCCCCCEEEEECCCCCEEEE WLPNDRIYTGPDGTDKNATRWLYYWGHSGVMDQVWRFNINYTRVSDPAYFTDLTSQYGST ECCCCCEEECCCCCCCCCEEEEEEECCCCHHHHHEEEEEEEEEECCCHHHHHHHHHHCCC TDGYATQIFTAGYANENWNATLSSKQFQVFTAAGNSNAYRAQPQLDMNYYKNDVGPFDMH CCCCEEEEEEECCCCCCCCEEECCCEEEEEEEECCCCCEECCCCCCHHHHHCCCCCEEEE VYGQAAKFTSVNPTNPEASRFHIEPTVNLPLSNSWGSINTEAKLLATHYQQDIPASFADN EEECCEEECCCCCCCCCCCEEEECEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCC ASNPKLKDSVNRVLPQFKVDGKVVFDRSMDWATGFTQTLEPRAQYLYVPYRNQDDIYIYD CCCCCHHHHHHHHCCCEECCCEEEEECCCCCCCCCHHHCCCCCCEEEEEECCCCCEEEEE TTLMQSDYSGLFRDRTYSGLDRIASANQVSTGLTSRIYDDARVERFNVSVGQIYYFSRSR EEEECCCCCHHHHCCCHHHHHHHHCCCHHHHCHHHHHHCCCCEEEEECEEEEEEEEECCC TGNTEAIDNSNATGSLVWAGDTFWRINDQLGLKGGAQYDTRLGSLTLGNAIMEYRKDADR CCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCHHCCCCCEEHHHHHHHHHCCCCE MIQLNYRYASPKYIQAAVPKVYNPDYQQGISQVGTTASWPIADRWAIVGAYYYDTKAKQP EEEEEEEECCCCHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCC ASQLVGLQYNTCCWAVNLGYERKITGWNAQGQTSKYDNKIGFNIELRGLSGGHSLGTAQM HHHHCCCEECCEEEEEECCCEEEECCCCCCCCCCCCCCEECEEEEEEECCCCCCCCHHHH LNSGILPYQSAF HHCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA