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The map label for this gene is pdxA [H]

Identifier: 108810532

GI number: 108810532

Start: 442979

End: 443983

Strand: Reverse

Name: pdxA [H]

Synonym: YPN_0367

Alternate gene names: 108810532

Gene position: 443983-442979 (Counterclockwise)

Preceding gene: 108810533

Following gene: 108810531

Centisome position: 9.79

GC content: 49.95

Gene sequence:

>1005_bases
ATGGTAGTAATGCACAACCACAATAATCGTCTAGTGATCACCCCCGGCGAGCCAGCCGGGGTCGGGCCGGATTTAGCCAT
CACTCTGGCTCAACAGGATTGGCCTGTTGAGCTGGTAGTCTGCGCGGATCCGGCCTTGCTACTGGCCCGAGCCAGCCAAC
TTAATCTGCCCCTGCAATTGCGTGAGTACCAAGCTGACCAGCCGGCAATAGCACAGCAAGCAGGGTCACTGACTATTTTA
CCTGTAAAAACAGCTGTTAATGTTGTCCCTGGCAAGCTTGATGTCGGTAACAGTCACTATGTGGTTGAAACGTTAGCCAA
GGCTTGTGATGGTGCGATCAGTGGTGAATTCGCTGCATTGGTCACGGGCCCGGTACAAAAAAGTATTATCAATGATGCCG
GCATCCCCTTCATTGGGCATACCGAATTCTTTGCTGACCGCAGCCACTGCCAGAGGGTGGTGATGATGCTGGCAACGGAA
GAGTTGCGTGTGGCTTTAGCGACCACCCACTTGCCATTATTGGCGGTGCCAGGTGCCATTACGCAAGCCAGCTTACATGA
AGTGATCACCATCCTTGATAACGACCTAAAAACCAAGTTTGGTATTACTCAGCCACAAATTTATGTTTGTGGGCTTAATC
CTCATGCTGGCGAAGGGGGACATATGGGCCATGAAGAGATCGATACAATTATTCCTGCCCTGAATACACTACGCCAGCAA
GGGATAAACCTCATTGGCCCACTACCAGCAGACACCCTGTTTCAGCCGAAATATCTGCAACATGCAGATGCCGTTCTCGC
GATGTATCACGATCAGGGGCTACCAGTATTGAAATATCAAGGGTTTGGCCGAGCAGTCAATATCACTCTCGGTTTGCCTT
TTATCCGCACTTCTGTGGATCACGGTACCGCTTTAGAACTCGCCGCAACCGGTACTGCCGATGTTGGCAGTTTCATTACG
GCATTAAACTTAGCCATCAAAATGATAAATAACAGCAATGAATAA

Upstream 100 bases:

>100_bases
AAAGAGCGGGCGTACCGTATGCTCTTCAACCGTAAATTTGCTGAAGAAGCACAAACCTGGATGCAAGAGCAGCGTGCTGC
TGCTTATGTAAAAATTCTTG

Downstream 100 bases:

>100_bases
TAGAGTCCACCAAGGGCATTTTGCCCGCAAACGCTTTGGACAAAACTTTTTAAACGATCAGTTTGTCATCGACAGTATTG
TCTCCGCAATCCACCCAGTT

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MVVMHNHNNRLVITPGEPAGVGPDLAITLAQQDWPVELVVCADPALLLARASQLNLPLQLREYQADQPAIAQQAGSLTIL
PVKTAVNVVPGKLDVGNSHYVVETLAKACDGAISGEFAALVTGPVQKSIINDAGIPFIGHTEFFADRSHCQRVVMMLATE
ELRVALATTHLPLLAVPGAITQASLHEVITILDNDLKTKFGITQPQIYVCGLNPHAGEGGHMGHEEIDTIIPALNTLRQQ
GINLIGPLPADTLFQPKYLQHADAVLAMYHDQGLPVLKYQGFGRAVNITLGLPFIRTSVDHGTALELAATGTADVGSFIT
ALNLAIKMINNSNE

Sequences:

>Translated_334_residues
MVVMHNHNNRLVITPGEPAGVGPDLAITLAQQDWPVELVVCADPALLLARASQLNLPLQLREYQADQPAIAQQAGSLTIL
PVKTAVNVVPGKLDVGNSHYVVETLAKACDGAISGEFAALVTGPVQKSIINDAGIPFIGHTEFFADRSHCQRVVMMLATE
ELRVALATTHLPLLAVPGAITQASLHEVITILDNDLKTKFGITQPQIYVCGLNPHAGEGGHMGHEEIDTIIPALNTLRQQ
GINLIGPLPADTLFQPKYLQHADAVLAMYHDQGLPVLKYQGFGRAVNITLGLPFIRTSVDHGTALELAATGTADVGSFIT
ALNLAIKMINNSNE
>Mature_334_residues
MVVMHNHNNRLVITPGEPAGVGPDLAITLAQQDWPVELVVCADPALLLARASQLNLPLQLREYQADQPAIAQQAGSLTIL
PVKTAVNVVPGKLDVGNSHYVVETLAKACDGAISGEFAALVTGPVQKSIINDAGIPFIGHTEFFADRSHCQRVVMMLATE
ELRVALATTHLPLLAVPGAITQASLHEVITILDNDLKTKFGITQPQIYVCGLNPHAGEGGHMGHEEIDTIIPALNTLRQQ
GINLIGPLPADTLFQPKYLQHADAVLAMYHDQGLPVLKYQGFGRAVNITLGLPFIRTSVDHGTALELAATGTADVGSFIT
ALNLAIKMINNSNE

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=74.2331288343558, Blast_Score=490, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 35600; Mature: 35600

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVMHNHNNRLVITPGEPAGVGPDLAITLAQQDWPVELVVCADPALLLARASQLNLPLQL
CEEEEECCCEEEEECCCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHCCCCEEE
REYQADQPAIAQQAGSLTILPVKTAVNVVPGKLDVGNSHYVVETLAKACDGAISGEFAAL
HHCCCCCCHHHHHCCCEEEEEEHHHHEECCCEEECCCCCHHHHHHHHHHCCCCCCCEEEE
VTGPVQKSIINDAGIPFIGHTEFFADRSHCQRVVMMLATEELRVALATTHLPLLAVPGAI
EECHHHHHHHHCCCCCEEECHHHHHCHHHHHHHHHHHHHHHHEEEEEECCCCEEECCCCH
TQASLHEVITILDNDLKTKFGITQPQIYVCGLNPHAGEGGHMGHEEIDTIIPALNTLRQQ
HHHHHHHHHHHHCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GINLIGPLPADTLFQPKYLQHADAVLAMYHDQGLPVLKYQGFGRAVNITLGLPFIRTSVD
CCCEECCCCCCCCCCCHHHHHHHHEEEEEECCCCCEEEECCCCCEEEEEEECCHHEECCC
HGTALELAATGTADVGSFITALNLAIKMINNSNE
CCCEEEEEECCCCHHHHHHHHHHHHHHEECCCCC
>Mature Secondary Structure
MVVMHNHNNRLVITPGEPAGVGPDLAITLAQQDWPVELVVCADPALLLARASQLNLPLQL
CEEEEECCCEEEEECCCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHCCCCEEE
REYQADQPAIAQQAGSLTILPVKTAVNVVPGKLDVGNSHYVVETLAKACDGAISGEFAAL
HHCCCCCCHHHHHCCCEEEEEEHHHHEECCCEEECCCCCHHHHHHHHHHCCCCCCCEEEE
VTGPVQKSIINDAGIPFIGHTEFFADRSHCQRVVMMLATEELRVALATTHLPLLAVPGAI
EECHHHHHHHHCCCCCEEECHHHHHCHHHHHHHHHHHHHHHHEEEEEECCCCEEECCCCH
TQASLHEVITILDNDLKTKFGITQPQIYVCGLNPHAGEGGHMGHEEIDTIIPALNTLRQQ
HHHHHHHHHHHHCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GINLIGPLPADTLFQPKYLQHADAVLAMYHDQGLPVLKYQGFGRAVNITLGLPFIRTSVD
CCCEECCCCCCCCCCCHHHHHHHHEEEEEECCCCCEEEECCCCCEEEEEEECCHHEECCC
HGTALELAATGTADVGSFITALNLAIKMINNSNE
CCCEEEEEECCCCHHHHHHHHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA