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The map label for this gene is tadA [H]

Identifier: 108801923

GI number: 108801923

Start: 5251900

End: 5252352

Strand: Reverse

Name: tadA [H]

Synonym: Mmcs_4960

Alternate gene names: 108801923

Gene position: 5252352-5251900 (Counterclockwise)

Preceding gene: 108801924

Following gene: 108801922

Centisome position: 92.06

GC content: 74.39

Gene sequence:

>453_bases
GTGACATCCGACGAATCCCTGATCCGCGCCGCGCTCGACGCCGCGGCGCTCGCCGGTCCGAGGGACGTGCCGATCGGCGC
GGTGGTGTTCGGCCCCGACGGCACCGAGTTGGCCCGCGCGGCGAATGCGCGTGAAGCACTGGGGGATCCGACGGCGCACG
CGGAGGTGCTGGCGCTGCGGGCGGCCGCGGCGGTCCTCGGCGACGGGTGGCGCCTGGAGGGGACGACGCTCGCGGTGACC
GTCGAACCGTGCACGATGTGCGCCGGTGCGCTGGTGCTGGCGCGGGTGGCCCGGGTGGTGTTCGGGGCGTGGGAACCCAA
GACGGGCGCGGTCGGCTCGCTGTGGGATGTCGTACGCGACCGCAGGCTCAACCACCGCCCCGGCGTGCGTGGCGGTGTAC
TGGCCGACGAGTGCGCGAAACCGTTGGAGGCGTTCTTCGCCCGGCAGCGCTGA

Upstream 100 bases:

>100_bases
TCGACGAGACCGATCTGTACGCCGACGAGCAACTCGGCCGCATCGCCCGTGAGATGGGCTTCGCCGACGAACTGTCCGCG
GTCCTCGACAAACTCAATCG

Downstream 100 bases:

>100_bases
TCGGCCGCCGGCGCGATTATGGGCTGCGGGGCCGGTTCGGTAAGCTGCCACACGGTGGCGTGTCCGAGCGGCCTAAGGAG
CACGCCTCGAAAGCGTGTGA

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTSDESLIRAALDAAALAGPRDVPIGAVVFGPDGTELARAANAREALGDPTAHAEVLALRAAAAVLGDGWRLEGTTLAVT
VEPCTMCAGALVLARVARVVFGAWEPKTGAVGSLWDVVRDRRLNHRPGVRGGVLADECAKPLEAFFARQR

Sequences:

>Translated_150_residues
MTSDESLIRAALDAAALAGPRDVPIGAVVFGPDGTELARAANAREALGDPTAHAEVLALRAAAAVLGDGWRLEGTTLAVT
VEPCTMCAGALVLARVARVVFGAWEPKTGAVGSLWDVVRDRRLNHRPGVRGGVLADECAKPLEAFFARQR
>Mature_149_residues
TSDESLIRAALDAAALAGPRDVPIGAVVFGPDGTELARAANAREALGDPTAHAEVLALRAAAAVLGDGWRLEGTTLAVTV
EPCTMCAGALVLARVARVVFGAWEPKTGAVGSLWDVVRDRRLNHRPGVRGGVLADECAKPLEAFFARQR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=149, Percent_Identity=46.3087248322148, Blast_Score=117, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17541138, Length=149, Percent_Identity=30.8724832214765, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15623; Mature: 15492

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDESLIRAALDAAALAGPRDVPIGAVVFGPDGTELARAANAREALGDPTAHAEVLALR
CCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
AAAAVLGDGWRLEGTTLAVTVEPCTMCAGALVLARVARVVFGAWEPKTGAVGSLWDVVRD
HHHHHHCCCEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
RRLNHRPGVRGGVLADECAKPLEAFFARQR
HCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSDESLIRAALDAAALAGPRDVPIGAVVFGPDGTELARAANAREALGDPTAHAEVLALR
CCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
AAAAVLGDGWRLEGTTLAVTVEPCTMCAGALVLARVARVVFGAWEPKTGAVGSLWDVVRD
HHHHHHCCCEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
RRLNHRPGVRGGVLADECAKPLEAFFARQR
HCCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]