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The map label for this gene is pyrD [H]

Identifier: 108801827

GI number: 108801827

Start: 5149461

End: 5150483

Strand: Reverse

Name: pyrD [H]

Synonym: Mmcs_4864

Alternate gene names: 108801827

Gene position: 5150483-5149461 (Counterclockwise)

Preceding gene: 108801828

Following gene: 108801825

Centisome position: 90.27

GC content: 69.79

Gene sequence:

>1023_bases
ATGGACCTGTCCACCCGCTACCTCGGGCTCGAACTGCGCAACCCGCTGCTGGCCGCGGCGTCACCGCTGAGCCGGACACT
CGACGGCGTCAAACAGCTCGCCGACGCGGGAGTCGGCGCGGTGGTGCTCTATTCGCTGTTCGAGGAACAACTGCGCCGCG
AAGCCGCCGACAATGCGCGGATGGCGACCTTCGCCAACGAAACCCACGCGGAGTCCGTGACGTATTTCCCGTCGACGGTC
GGCGAGGGGGACGGTGCTCGGCGCCACCTGCGGCTGCTGGAACGCGCCGCAGCGGAGGTCGAGGTCCCGGTCATCGGCAG
CCTCAACGGCTCGACCCCCGGCGGCTGGGTCCGCCACGCCCGGGCGATGGAGGACGCCGGGGCCGCGGCGATCGAGCTCA
ACATCTACCAGTTGCCCGGCGATTCCCACATCAGCGGCCGGGAGGTCGAGCAACGCCACCTCGACATCCTCGCCGCGGTC
AAGGACACGGTGGACCTGCCGGTGGCCGTCAAGCTGAGCCCCTTCTTCAGCGCGACCGCGGAGATGGCGCTGCGGCTCGA
CCAGGCCGGTGCGGACGGGTTGGTGCTGTTCAACCGGTTCCTGCAACCCGACATCGACAGCGAGACCATCAGTGTGACCT
CCGAGGTGACGCTGTCGGTTCCCGCGGAAGCGCGGCTTCCCCGGACGTGGATCGCGCTGCTGCGGGGCAGGATCGATGCC
TCACTGGCCGCGACGACCGGTGTCGAGGACGCCGGCGACGTCGCCAAGTATCTGCTGGCGGGCGCCGATGTGGTGCAGAC
GGCCTCGGCGCTGTTGCGGCACGGTCCCGAATACGCCGGCGTCCTGCTCACCGGTCTGTCCGACTGGCTGGCCAGGAAGA
GTTTTCACGCACTGCATCAGGTGCGCGGGAAGCTCGCCGTGCCGTTCGGCGTGGACGAGACGGCTCGCGAACGCGCCGAC
TATGTCGGCGCACTGTGGCAGGCCAACACCGGCGCGCCCGGGACGGTCAGCGCGGCGGAGTGA

Upstream 100 bases:

>100_bases
TGGCCCAGCAGTCGGTGGCGCGGCGGTGGGACACCTACGAGCAGATGGCGGCCGCGAGCCCGCACGAGTTCCCGTCCGAT
GCGCGAAAGGGTGGTGACTG

Downstream 100 bases:

>100_bases
GACCCGGGTACGCCGGGGGTGTGGGCACCAGACGCGCCAGCGCGCGCCGGTGCCGTTCGGCCAGCACAGCGGCCAGCACG
TACTGCGGTGGAGTACCGGG

Product: dihydroorotate dehydrogenase 2

Products: NA

Alternate protein names: DHOdehase; DHOD; DHODase; Dihydroorotate oxidase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MDLSTRYLGLELRNPLLAAASPLSRTLDGVKQLADAGVGAVVLYSLFEEQLRREAADNARMATFANETHAESVTYFPSTV
GEGDGARRHLRLLERAAAEVEVPVIGSLNGSTPGGWVRHARAMEDAGAAAIELNIYQLPGDSHISGREVEQRHLDILAAV
KDTVDLPVAVKLSPFFSATAEMALRLDQAGADGLVLFNRFLQPDIDSETISVTSEVTLSVPAEARLPRTWIALLRGRIDA
SLAATTGVEDAGDVAKYLLAGADVVQTASALLRHGPEYAGVLLTGLSDWLARKSFHALHQVRGKLAVPFGVDETARERAD
YVGALWQANTGAPGTVSAAE

Sequences:

>Translated_340_residues
MDLSTRYLGLELRNPLLAAASPLSRTLDGVKQLADAGVGAVVLYSLFEEQLRREAADNARMATFANETHAESVTYFPSTV
GEGDGARRHLRLLERAAAEVEVPVIGSLNGSTPGGWVRHARAMEDAGAAAIELNIYQLPGDSHISGREVEQRHLDILAAV
KDTVDLPVAVKLSPFFSATAEMALRLDQAGADGLVLFNRFLQPDIDSETISVTSEVTLSVPAEARLPRTWIALLRGRIDA
SLAATTGVEDAGDVAKYLLAGADVVQTASALLRHGPEYAGVLLTGLSDWLARKSFHALHQVRGKLAVPFGVDETARERAD
YVGALWQANTGAPGTVSAAE
>Mature_340_residues
MDLSTRYLGLELRNPLLAAASPLSRTLDGVKQLADAGVGAVVLYSLFEEQLRREAADNARMATFANETHAESVTYFPSTV
GEGDGARRHLRLLERAAAEVEVPVIGSLNGSTPGGWVRHARAMEDAGAAAIELNIYQLPGDSHISGREVEQRHLDILAAV
KDTVDLPVAVKLSPFFSATAEMALRLDQAGADGLVLFNRFLQPDIDSETISVTSEVTLSVPAEARLPRTWIALLRGRIDA
SLAATTGVEDAGDVAKYLLAGADVVQTASALLRHGPEYAGVLLTGLSDWLARKSFHALHQVRGKLAVPFGVDETARERAD
YVGALWQANTGAPGTVSAAE

Specific function: Unknown

COG id: COG0167

COG function: function code F; Dihydroorotate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082059, Length=327, Percent_Identity=25.0764525993884, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005720
- InterPro:   IPR012135
- InterPro:   IPR001295 [H]

Pfam domain/function: PF01180 DHO_dh [H]

EC number: =1.3.3.1 [H]

Molecular weight: Translated: 36198; Mature: 36198

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSTRYLGLELRNPLLAAASPLSRTLDGVKQLADAGVGAVVLYSLFEEQLRREAADNAR
CCCCCCEECHHHCCCHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
MATFANETHAESVTYFPSTVGEGDGARRHLRLLERAAAEVEVPVIGSLNGSTPGGWVRHA
EEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHH
RAMEDAGAAAIELNIYQLPGDSHISGREVEQRHLDILAAVKDTVDLPVAVKLSPFFSATA
HHHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHH
EMALRLDQAGADGLVLFNRFLQPDIDSETISVTSEVTLSVPAEARLPRTWIALLRGRIDA
HHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHCCCH
SLAATTGVEDAGDVAKYLLAGADVVQTASALLRHGPEYAGVLLTGLSDWLARKSFHALHQ
HHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRGKLAVPFGVDETARERADYVGALWQANTGAPGTVSAAE
HCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDLSTRYLGLELRNPLLAAASPLSRTLDGVKQLADAGVGAVVLYSLFEEQLRREAADNAR
CCCCCCEECHHHCCCHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
MATFANETHAESVTYFPSTVGEGDGARRHLRLLERAAAEVEVPVIGSLNGSTPGGWVRHA
EEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHH
RAMEDAGAAAIELNIYQLPGDSHISGREVEQRHLDILAAVKDTVDLPVAVKLSPFFSATA
HHHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHH
EMALRLDQAGADGLVLFNRFLQPDIDSETISVTSEVTLSVPAEARLPRTWIALLRGRIDA
HHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHCCCH
SLAATTGVEDAGDVAKYLLAGADVVQTASALLRHGPEYAGVLLTGLSDWLARKSFHALHQ
HHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRGKLAVPFGVDETARERADYVGALWQANTGAPGTVSAAE
HCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]