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The map label for this gene is hemK [C]

Identifier: 108801815

GI number: 108801815

Start: 5139010

End: 5139705

Strand: Reverse

Name: hemK [C]

Synonym: Mmcs_4852

Alternate gene names: 108801815

Gene position: 5139705-5139010 (Counterclockwise)

Preceding gene: 108801817

Following gene: 108801810

Centisome position: 90.08

GC content: 69.83

Gene sequence:

>696_bases
GTGACGACTGCATACACCGACGAGCGCGACACCGTGGTCGCCGCGGACGGCGTGTACGCCCCGCAGGAAGATTCGCAACT
GCTGGTCGACATCATGGAGAAGACCGGTCTCGCCGTCGGTCGCCGTGCCGTCGACTTGTGCACAGGCAGTGGAGTGGTGG
CGGTCAACGCCGCCCTGCAGGGTGCCTCGTCGGTCACCGCCTTCGACATCTGCCCGCGCGCTGTGCGATGCGCACGCGGC
AATGCGCTCGGAGCCGGGGTCGATGTGGACGTCCACCTCGGATCTTGGGCGCGGGCAGTGGAATTCGACCCGTTCGACCT
GGTGACGTGCAACCCGCCGTACGTCCCGCACGCCCCCGAAGCCGACCGGGAGCCGGTGCCGTCGAGCGTCGGCCCGGCCC
GCGCGTGGGACGCCGGCTACGACGGGCGCATGATCCTCGACCCGCTGTGCGAGGCGGTGCCCGATCTGCTCGCCTCCGGT
GGCAGCCTGCTTCTCGTACAGTCCGAGTTCGCCGATCCGCGCCGCACCCTGGCAGCCCTGTCGAGCGCCGGGCTGGACGC
CGAAGTGATTGCCTGGCAATGGATCCCGTTCGGCCCCGTGCTCAACGCGCGGGCCGAATGGCTCGAGGAGACCGGGCGCC
TGGATCCGGGTCGGCGCGAGGAAGAGCTGTTGGTCATCCGAGCGGACAAACCGTGA

Upstream 100 bases:

>100_bases
CCGCCCTAACACGAGCGCAAACGGGGTGTGCTGGTTTAACAACCGCGATACAGGGCATTAATCACCGCAGCTAATGACCC
CTTGACGTCGAGAGGCCGAT

Downstream 100 bases:

>100_bases
CCGAACCGCGCACCGTGCGGGTGGTGCAGGGCGGGCCCATCATGGTCGAGGGCCCCGTCCGCATCGAGATGCCCGACGGC
AGCATCGTGGAATCCGACCG

Product: putative methylase

Products: NA

Alternate protein names: M.MjaHemkP [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTTAYTDERDTVVAADGVYAPQEDSQLLVDIMEKTGLAVGRRAVDLCTGSGVVAVNAALQGASSVTAFDICPRAVRCARG
NALGAGVDVDVHLGSWARAVEFDPFDLVTCNPPYVPHAPEADREPVPSSVGPARAWDAGYDGRMILDPLCEAVPDLLASG
GSLLLVQSEFADPRRTLAALSSAGLDAEVIAWQWIPFGPVLNARAEWLEETGRLDPGRREEELLVIRADKP

Sequences:

>Translated_231_residues
MTTAYTDERDTVVAADGVYAPQEDSQLLVDIMEKTGLAVGRRAVDLCTGSGVVAVNAALQGASSVTAFDICPRAVRCARG
NALGAGVDVDVHLGSWARAVEFDPFDLVTCNPPYVPHAPEADREPVPSSVGPARAWDAGYDGRMILDPLCEAVPDLLASG
GSLLLVQSEFADPRRTLAALSSAGLDAEVIAWQWIPFGPVLNARAEWLEETGRLDPGRREEELLVIRADKP
>Mature_230_residues
TTAYTDERDTVVAADGVYAPQEDSQLLVDIMEKTGLAVGRRAVDLCTGSGVVAVNAALQGASSVTAFDICPRAVRCARGN
ALGAGVDVDVHLGSWARAVEFDPFDLVTCNPPYVPHAPEADREPVPSSVGPARAWDAGYDGRMILDPLCEAVPDLLASGG
SLLLVQSEFADPRRTLAALSSAGLDAEVIAWQWIPFGPVLNARAEWLEETGRLDPGRREEELLVIRADKP

Specific function: Putative protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Drosophila melanogaster, GI78706836, Length=209, Percent_Identity=30.622009569378, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004557
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 24566; Mature: 24435

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAYTDERDTVVAADGVYAPQEDSQLLVDIMEKTGLAVGRRAVDLCTGSGVVAVNAALQ
CCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCHHHCCHHHEEECCCCEEEEEEECC
GASSVTAFDICPRAVRCARGNALGAGVDVDVHLGSWARAVEFDPFDLVTCNPPYVPHAPE
CCCCCCHHHHCHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCEEEECCCCCCCCCCC
ADREPVPSSVGPARAWDAGYDGRMILDPLCEAVPDLLASGGSLLLVQSEFADPRRTLAAL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
SSAGLDAEVIAWQWIPFGPVLNARAEWLEETGRLDPGRREEELLVIRADKP
HHCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
TTAYTDERDTVVAADGVYAPQEDSQLLVDIMEKTGLAVGRRAVDLCTGSGVVAVNAALQ
CCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCHHHCCHHHEEECCCCEEEEEEECC
GASSVTAFDICPRAVRCARGNALGAGVDVDVHLGSWARAVEFDPFDLVTCNPPYVPHAPE
CCCCCCHHHHCHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCEEEECCCCCCCCCCC
ADREPVPSSVGPARAWDAGYDGRMILDPLCEAVPDLLASGGSLLLVQSEFADPRRTLAAL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
SSAGLDAEVIAWQWIPFGPVLNARAEWLEETGRLDPGRREEELLVIRADKP
HHCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]