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The map label for this gene is hsaB [H]

Identifier: 108801669

GI number: 108801669

Start: 4986495

End: 4987109

Strand: Reverse

Name: hsaB [H]

Synonym: Mmcs_4706

Alternate gene names: 108801669

Gene position: 4987109-4986495 (Counterclockwise)

Preceding gene: 108801670

Following gene: 108801668

Centisome position: 87.41

GC content: 65.85

Gene sequence:

>615_bases
GTGGGGTCACGACTTCAGCGTCGGCTTCAAGTAGGCCGCGGACGCACCGTGACCGAGACGAGCATCGACCCGCGCACGTT
CCGCAACGTGCTCGGCCAGTTCTGCACCGGCATCACGGTGATCACGACCATGCACGACGGCGCACCGGTCGGGTTCGCCT
GTCAGTCGTTCGCCGCGCTGTCTCTCGAACCGCCACTGGTGTTGTTCTGCCCGACCAAGGTGTCGCGGTCCTGGAAGGCG
ATCGAGGCCAGCGGCCGGTTCTGCGTGAACGTGTTGCACGAGAAGCAGAAAGACGTCTCCGCGCGGTTCGGCTCACGCGA
ACCGGACAAGTTCGCCGGCATCGACTGGACACCGTCGAAGCTGGGCTCGCCGATCATCGACGGCAACCTGGCACACATCG
ACTGCACGGTGCACTCGGTGCACGACGGCGGTGACCACCTGGTGGTGTTCGGCGCCGTGCACTCGCTGTCGGAGGTGCCG
AAGAAGAAGCCGCGGCCGCTGCTGTTCTACCGCGGCGAGTACACCGGCATCGAACCCGACAAGAACTCGCCGGCGCACTG
GCGCGACGATCTCGAGGCGTTCCTCACGGCCACAACTCCGGACACCTGGCTGTAG

Upstream 100 bases:

>100_bases
ACATGAAGACGCCGGGCGGTTTCGACGTCGAATTCGGTTGCGAGGGGCTCGAAGTCGAGGACGAGAACTGGATCGCCCGG
GAGAGCACCGCGGTCAGCCT

Downstream 100 bases:

>100_bases
TCCATGACATATTGACGGTTGTGTCGAACACCGTCATGCGGTCGTCAGCCGCGATCTGCGCACTCCTGCTTGCCGCGGGG
TGCTCCGAAAACCGCCAGGG

Product: flavin reductase-like, FMN-binding protein

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MGSRLQRRLQVGRGRTVTETSIDPRTFRNVLGQFCTGITVITTMHDGAPVGFACQSFAALSLEPPLVLFCPTKVSRSWKA
IEASGRFCVNVLHEKQKDVSARFGSREPDKFAGIDWTPSKLGSPIIDGNLAHIDCTVHSVHDGGDHLVVFGAVHSLSEVP
KKKPRPLLFYRGEYTGIEPDKNSPAHWRDDLEAFLTATTPDTWL

Sequences:

>Translated_204_residues
MGSRLQRRLQVGRGRTVTETSIDPRTFRNVLGQFCTGITVITTMHDGAPVGFACQSFAALSLEPPLVLFCPTKVSRSWKA
IEASGRFCVNVLHEKQKDVSARFGSREPDKFAGIDWTPSKLGSPIIDGNLAHIDCTVHSVHDGGDHLVVFGAVHSLSEVP
KKKPRPLLFYRGEYTGIEPDKNSPAHWRDDLEAFLTATTPDTWL
>Mature_203_residues
GSRLQRRLQVGRGRTVTETSIDPRTFRNVLGQFCTGITVITTMHDGAPVGFACQSFAALSLEPPLVLFCPTKVSRSWKAI
EASGRFCVNVLHEKQKDVSARFGSREPDKFAGIDWTPSKLGSPIIDGNLAHIDCTVHSVHDGGDHLVVFGAVHSLSEVPK
KKPRPLLFYRGEYTGIEPDKNSPAHWRDDLEAFLTATTPDTWL

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

Organism=Escherichia coli, GI87081819, Length=155, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 22513; Mature: 22382

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSRLQRRLQVGRGRTVTETSIDPRTFRNVLGQFCTGITVITTMHDGAPVGFACQSFAAL
CCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHEE
SLEPPLVLFCPTKVSRSWKAIEASGRFCVNVLHEKQKDVSARFGSREPDKFAGIDWTPSK
CCCCCEEEECCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
LGSPIIDGNLAHIDCTVHSVHDGGDHLVVFGAVHSLSEVPKKKPRPLLFYRGEYTGIEPD
HCCCEECCCEEEEEEEEEEECCCCCEEEEEECHHHHHHCCCCCCCCEEEECCCCCCCCCC
KNSPAHWRDDLEAFLTATTPDTWL
CCCCCCHHHHHHHEEECCCCCCCC
>Mature Secondary Structure 
GSRLQRRLQVGRGRTVTETSIDPRTFRNVLGQFCTGITVITTMHDGAPVGFACQSFAAL
CHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHEE
SLEPPLVLFCPTKVSRSWKAIEASGRFCVNVLHEKQKDVSARFGSREPDKFAGIDWTPSK
CCCCCEEEECCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
LGSPIIDGNLAHIDCTVHSVHDGGDHLVVFGAVHSLSEVPKKKPRPLLFYRGEYTGIEPD
HCCCEECCCEEEEEEEEEEECCCCCEEEEEECHHHHHHCCCCCCCCEEEECCCCCCCCCC
KNSPAHWRDDLEAFLTATTPDTWL
CCCCCCHHHHHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]