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The map label for this gene is mhpD3 [H]

Identifier: 108801624

GI number: 108801624

Start: 4938281

End: 4939066

Strand: Reverse

Name: mhpD3 [H]

Synonym: Mmcs_4661

Alternate gene names: 108801624

Gene position: 4939066-4938281 (Counterclockwise)

Preceding gene: 108801627

Following gene: 108801623

Centisome position: 86.57

GC content: 64.12

Gene sequence:

>786_bases
ATGCTCAGTTCCGAGGTACGTGAGCAGCTTGCCGCCGACCTTGCCCAAGCCGAGCGCAGCCGGGTGCCGATGAAACCCCT
GACCGACGGTCACCCCGACATCGATGTAGTGGACGCCTACGAGATCCAGCTGATCAACATCCGCCAGAAAGTCGCCGAAG
GCGCCCGGGTGATCGGCCACAAAGTCGGCCTCTCCTCGGAGGCGATGCAGAAGATGATGGGCGTCGACGAACCCGACTAC
GGCCACCTGCTCGACGATATGCAGGTCTACGAGGACAAACCGGTCAAGAGCTCCAATTACCTCTATCCCCGGGTCGAGGT
CGAGGTCGGCTTCATCCTGGCCGACGACCTGCCGGGTGCGGGCTGCACCGAGGAGGACGTCCTCGCCGCGACTGCGGCGT
TCGCCCCCGCGATCGAGTTGATCGACACCCGCATCACCGATTGGAAGATCAAACTCTGCGACACCATCGCCGACAACGCG
TCGTCGGCGGGATGGGTGCTCGGCGAAGCCCGGGTGTCGCCCAAGGACATCGACATCAAGTCGATCGACGCCGTACTGAC
CAACAACGGTGAGACGGTGGCCGAAGGCCGCAGCGATGCGGTGCTGGGCAATCCGGTCACCGCGGTGGCGTGGCTGGCCC
GCAAGGTCGAGAGTTTCGGCGTCCGCCTCAAGGCCGGCGACATCGTGTTGCCGGGCTCGTGCACGCGTGCGATAGATGCA
CCTCCCGGGAGCCATTTCGTCGCCGACTTCGCCGGGTTAGGTTCAGTACAACTCGCTTTCGAGTGA

Upstream 100 bases:

>100_bases
GACGACGTCGTACTCCTGTCCGGTCATGTAGAACACGTTATAGAATTGCCCGGCCGACCCACAACTGCGCCGGTCGACGA
AACGAGGGGACTTCACCTAG

Downstream 100 bases:

>100_bases
GCGCTTTTCAGAAACCAGGGAGAGTCATATGCCGGAGAAGCTTCAGGTCGCGATCGTCGGGTCCGGCAACATCAGCACCG
ATCTGCTGTACAAGCTGCAG

Product: 4-oxalocrotonate decarboxylase

Products: NA

Alternate protein names: 2-hydroxypentadienoic acid hydratase 3 [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MLSSEVREQLAADLAQAERSRVPMKPLTDGHPDIDVVDAYEIQLINIRQKVAEGARVIGHKVGLSSEAMQKMMGVDEPDY
GHLLDDMQVYEDKPVKSSNYLYPRVEVEVGFILADDLPGAGCTEEDVLAATAAFAPAIELIDTRITDWKIKLCDTIADNA
SSAGWVLGEARVSPKDIDIKSIDAVLTNNGETVAEGRSDAVLGNPVTAVAWLARKVESFGVRLKAGDIVLPGSCTRAIDA
PPGSHFVADFAGLGSVQLAFE

Sequences:

>Translated_261_residues
MLSSEVREQLAADLAQAERSRVPMKPLTDGHPDIDVVDAYEIQLINIRQKVAEGARVIGHKVGLSSEAMQKMMGVDEPDY
GHLLDDMQVYEDKPVKSSNYLYPRVEVEVGFILADDLPGAGCTEEDVLAATAAFAPAIELIDTRITDWKIKLCDTIADNA
SSAGWVLGEARVSPKDIDIKSIDAVLTNNGETVAEGRSDAVLGNPVTAVAWLARKVESFGVRLKAGDIVLPGSCTRAIDA
PPGSHFVADFAGLGSVQLAFE
>Mature_261_residues
MLSSEVREQLAADLAQAERSRVPMKPLTDGHPDIDVVDAYEIQLINIRQKVAEGARVIGHKVGLSSEAMQKMMGVDEPDY
GHLLDDMQVYEDKPVKSSNYLYPRVEVEVGFILADDLPGAGCTEEDVLAATAAFAPAIELIDTRITDWKIKLCDTIADNA
SSAGWVLGEARVSPKDIDIKSIDAVLTNNGETVAEGRSDAVLGNPVTAVAWLARKVESFGVRLKAGDIVLPGSCTRAIDA
PPGSHFVADFAGLGSVQLAFE

Specific function: Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family. MhpD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=259, Percent_Identity=38.6100386100386, Blast_Score=187, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.2.1.80 [H]

Molecular weight: Translated: 27961; Mature: 27961

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSEVREQLAADLAQAERSRVPMKPLTDGHPDIDVVDAYEIQLINIRQKVAEGARVIGH
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCEEEEEEHHHHHHHHHHHHHHH
KVGLSSEAMQKMMGVDEPDYGHLLDDMQVYEDKPVKSSNYLYPRVEVEVGFILADDLPGA
HCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEECEEEEEEEEEEEECCCCCC
GCTEEDVLAATAAFAPAIELIDTRITDWKIKLCDTIADNASSAGWVLGEARVSPKDIDIK
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCEEEEECCCCCCCCCHH
SIDAVLTNNGETVAEGRSDAVLGNPVTAVAWLARKVESFGVRLKAGDIVLPGSCTRAIDA
HHHEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCEEEECCCEEECCCCCCCCCC
PPGSHFVADFAGLGSVQLAFE
CCCCHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MLSSEVREQLAADLAQAERSRVPMKPLTDGHPDIDVVDAYEIQLINIRQKVAEGARVIGH
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCEEEEEEHHHHHHHHHHHHHHH
KVGLSSEAMQKMMGVDEPDYGHLLDDMQVYEDKPVKSSNYLYPRVEVEVGFILADDLPGA
HCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEECEEEEEEEEEEEECCCCCC
GCTEEDVLAATAAFAPAIELIDTRITDWKIKLCDTIADNASSAGWVLGEARVSPKDIDIK
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCEEEEECCCCCCCCCHH
SIDAVLTNNGETVAEGRSDAVLGNPVTAVAWLARKVESFGVRLKAGDIVLPGSCTRAIDA
HHHEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCEEEECCCEEECCCCCCCCCC
PPGSHFVADFAGLGSVQLAFE
CCCCHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791097; 12823813 [H]