| Definition | Mycobacterium sp. MCS chromosome, complete genome. |
|---|---|
| Accession | NC_008146 |
| Length | 5,705,448 |
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The map label for this gene is fabG [H]
Identifier: 108801583
GI number: 108801583
Start: 4893369
End: 4894292
Strand: Reverse
Name: fabG [H]
Synonym: Mmcs_4620
Alternate gene names: 108801583
Gene position: 4894292-4893369 (Counterclockwise)
Preceding gene: 108801584
Following gene: 108801582
Centisome position: 85.78
GC content: 69.7
Gene sequence:
>924_bases GTGACGACTCCCCGTAACGACCTGACCGATCTGTCCGGCCGCGTCGCCGTGGTGACGGGCGCCGCAGCCGGCCTGGGACG CGCCGAGGCGATCGGGCTGGCCGCCGCAGGCGCCACCGTGGTGGTCAACGACATGTCCGCCTCGCTCGACGCCTCCGACG TCCTCGACGAGATCGCCGCCGCCGGGTCCAAGGGCGTCGCCGTCGCCGGTGACATCAGCCAGCGCTCGACCGCCGACGAA CTCGTCGAGACCGCCGACGGACTCGGCGGGTTGAACATCGTCGTCAACAACGCGGGCATCACCCGCGACCGGATCCTGTT CAACATGTCCGACGAGGAATGGGACGCGGTGATCGCGGTCCATCTCCGCGGGCACTTCCTGCTGACCCGCAATGCGGCCA CCTACTGGCGCGCCAAGGCCAAGGCGGGCGACGGGAAGGTCTACGGCCGCATCGTCAACACCTCGTCGGAGGCGGGTCTG TCGGGTCCGGTCGGTCAGCCCAACTACGGGGCGGCCAAGGCGGGCATCACCGCGCTGACGCTGTCCGCGGCCCGGGCGCT CGACCGGTTCGGGGTGCGGGCGAACGCGATCGCTCCCCGGGCCAGGACCGCGATGACCGCCGGGGTGTTCGGGGAAGCGC CCGACCCCTCGACCGATGGGATCGACCCGCTGTCGACCGACCATGTCGTCACGTTGGTGCGGTTTCTCGCGTCGCCTGCA TCGGAAGCGGTCAACGGGCAGCTGTTCATCGTCTACGGTCCGAAGGTGACGTTGGTGGCGGCACCCGTCGCGGAGGCCCA CTTCGCGGCGGAATCCGACGCGTGGGACCTGGACGACCTGAGCGAAACGTTGCGGGGTTACTTTGCTGATCGCGACCCCG AGCGTGGATTCTCGGCAACCGCGCTGATGGAGTCGCGAGACTGA
Upstream 100 bases:
>100_bases ACGACCCGGTGCCCGCCGACATGGAAGACGTGGCCGAGCAGTCGATCGCCGAGTGCCCGCGCGCCGCCTTGAACCGCAGA GACTAGAGGTATTCATAAAA
Downstream 100 bases:
>100_bases CAGTCTCGGTTGTCATGCCTCTGATCGAGGTAGAACACGTTACAGAATGACCTGGATCACACCTGCGTTGACCTGCGCAA ATAGGGGCGTGACGACGGAT
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 307; Mature: 306
Protein sequence:
>307_residues MTTPRNDLTDLSGRVAVVTGAAAGLGRAEAIGLAAAGATVVVNDMSASLDASDVLDEIAAAGSKGVAVAGDISQRSTADE LVETADGLGGLNIVVNNAGITRDRILFNMSDEEWDAVIAVHLRGHFLLTRNAATYWRAKAKAGDGKVYGRIVNTSSEAGL SGPVGQPNYGAAKAGITALTLSAARALDRFGVRANAIAPRARTAMTAGVFGEAPDPSTDGIDPLSTDHVVTLVRFLASPA SEAVNGQLFIVYGPKVTLVAAPVAEAHFAAESDAWDLDDLSETLRGYFADRDPERGFSATALMESRD
Sequences:
>Translated_307_residues MTTPRNDLTDLSGRVAVVTGAAAGLGRAEAIGLAAAGATVVVNDMSASLDASDVLDEIAAAGSKGVAVAGDISQRSTADE LVETADGLGGLNIVVNNAGITRDRILFNMSDEEWDAVIAVHLRGHFLLTRNAATYWRAKAKAGDGKVYGRIVNTSSEAGL SGPVGQPNYGAAKAGITALTLSAARALDRFGVRANAIAPRARTAMTAGVFGEAPDPSTDGIDPLSTDHVVTLVRFLASPA SEAVNGQLFIVYGPKVTLVAAPVAEAHFAAESDAWDLDDLSETLRGYFADRDPERGFSATALMESRD >Mature_306_residues TTPRNDLTDLSGRVAVVTGAAAGLGRAEAIGLAAAGATVVVNDMSASLDASDVLDEIAAAGSKGVAVAGDISQRSTADEL VETADGLGGLNIVVNNAGITRDRILFNMSDEEWDAVIAVHLRGHFLLTRNAATYWRAKAKAGDGKVYGRIVNTSSEAGLS GPVGQPNYGAAKAGITALTLSAARALDRFGVRANAIAPRARTAMTAGVFGEAPDPSTDGIDPLSTDHVVTLVRFLASPAS EAVNGQLFIVYGPKVTLVAAPVAEAHFAAESDAWDLDDLSETLRGYFADRDPERGFSATALMESRD
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI4504505, Length=250, Percent_Identity=41.6, Blast_Score=150, Evalue=1e-36, Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=37.8378378378378, Blast_Score=121, Evalue=7e-28, Organism=Homo sapiens, GI31542939, Length=249, Percent_Identity=32.5301204819277, Blast_Score=88, Evalue=1e-17, Organism=Homo sapiens, GI209862901, Length=199, Percent_Identity=34.6733668341709, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI19923983, Length=199, Percent_Identity=34.6733668341709, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI224922801, Length=185, Percent_Identity=33.5135135135135, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI4758504, Length=235, Percent_Identity=31.4893617021277, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=29.7619047619048, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI83715985, Length=230, Percent_Identity=29.5652173913043, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI40254992, Length=190, Percent_Identity=30.5263157894737, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=33.0708661417323, Blast_Score=107, Evalue=8e-25, Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=30.1960784313725, Blast_Score=99, Evalue=4e-22, Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=29.8449612403101, Blast_Score=98, Evalue=8e-22, Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=27.5590551181102, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=28.8461538461538, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=28.9795918367347, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI2367175, Length=188, Percent_Identity=32.9787234042553, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1786812, Length=194, Percent_Identity=31.9587628865979, Blast_Score=69, Evalue=5e-13, Organism=Escherichia coli, GI1789378, Length=194, Percent_Identity=31.4432989690722, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=29.3172690763052, Blast_Score=65, Evalue=8e-12, Organism=Escherichia coli, GI1789057, Length=267, Percent_Identity=27.3408239700375, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17568967, Length=248, Percent_Identity=37.5, Blast_Score=140, Evalue=1e-33, Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=36.2204724409449, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=33.4645669291339, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562906, Length=217, Percent_Identity=34.1013824884793, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17562908, Length=217, Percent_Identity=34.5622119815668, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17564282, Length=216, Percent_Identity=29.1666666666667, Blast_Score=81, Evalue=8e-16, Organism=Caenorhabditis elegans, GI193204405, Length=204, Percent_Identity=32.3529411764706, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=29.7297297297297, Blast_Score=77, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17559104, Length=201, Percent_Identity=32.8358208955224, Blast_Score=77, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17562910, Length=279, Percent_Identity=28.3154121863799, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17531453, Length=200, Percent_Identity=35.5, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17538480, Length=197, Percent_Identity=32.48730964467, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17538182, Length=199, Percent_Identity=32.1608040201005, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17560332, Length=202, Percent_Identity=30.1980198019802, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17562990, Length=200, Percent_Identity=32.5, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17560676, Length=195, Percent_Identity=31.7948717948718, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17560150, Length=217, Percent_Identity=30.4147465437788, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17560220, Length=233, Percent_Identity=29.6137339055794, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17555612, Length=219, Percent_Identity=31.5068493150685, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI193203117, Length=250, Percent_Identity=27.6, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193203115, Length=245, Percent_Identity=28.1632653061224, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71997099, Length=207, Percent_Identity=31.4009661835749, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17544670, Length=205, Percent_Identity=28.780487804878, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=27.9245283018868, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=241, Percent_Identity=37.344398340249, Blast_Score=139, Evalue=4e-34, Organism=Drosophila melanogaster, GI18859837, Length=239, Percent_Identity=40.1673640167364, Blast_Score=133, Evalue=2e-31, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=36.5461847389558, Blast_Score=109, Evalue=3e-24, Organism=Drosophila melanogaster, GI17737361, Length=192, Percent_Identity=36.4583333333333, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI23397609, Length=191, Percent_Identity=34.5549738219895, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24644339, Length=196, Percent_Identity=32.6530612244898, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24665243, Length=276, Percent_Identity=30.0724637681159, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI24665247, Length=271, Percent_Identity=30.9963099630996, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI221331218, Length=265, Percent_Identity=29.4339622641509, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI28571526, Length=196, Percent_Identity=29.5918367346939, Blast_Score=68, Evalue=1e-11, Organism=Drosophila melanogaster, GI221331216, Length=260, Percent_Identity=30.3846153846154, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21357041, Length=189, Percent_Identity=31.7460317460317, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 31670; Mature: 31538
Theoretical pI: Translated: 4.50; Mature: 4.50
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 1.6 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 1.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTTPRNDLTDLSGRVAVVTGAAAGLGRAEAIGLAAAGATVVVNDMSASLDASDVLDEIAA CCCCCCCHHHCCCCEEEEEECCCCCCCHHHHEEEECCCEEEEECCCCCCCHHHHHHHHHH AGSKGVAVAGDISQRSTADELVETADGLGGLNIVVNNAGITRDRILFNMSDEEWDAVIAV CCCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCCEEEEE HLRGHFLLTRNAATYWRAKAKAGDGKVYGRIVNTSSEAGLSGPVGQPNYGAAKAGITALT EECCEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHCHHHHH LSAARALDRFGVRANAIAPRARTAMTAGVFGEAPDPSTDGIDPLSTDHVVTLVRFLASPA HHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCH SEAVNGQLFIVYGPKVTLVAAPVAEAHFAAESDAWDLDDLSETLRGYFADRDPERGFSAT HHHHCCEEEEEECCEEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEE ALMESRD EEECCCC >Mature Secondary Structure TTPRNDLTDLSGRVAVVTGAAAGLGRAEAIGLAAAGATVVVNDMSASLDASDVLDEIAA CCCCCCHHHCCCCEEEEEECCCCCCCHHHHEEEECCCEEEEECCCCCCCHHHHHHHHHH AGSKGVAVAGDISQRSTADELVETADGLGGLNIVVNNAGITRDRILFNMSDEEWDAVIAV CCCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCCEEEEE HLRGHFLLTRNAATYWRAKAKAGDGKVYGRIVNTSSEAGLSGPVGQPNYGAAKAGITALT EECCEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHCHHHHH LSAARALDRFGVRANAIAPRARTAMTAGVFGEAPDPSTDGIDPLSTDHVVTLVRFLASPA HHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCH SEAVNGQLFIVYGPKVTLVAAPVAEAHFAAESDAWDLDDLSETLRGYFADRDPERGFSAT HHHHCCEEEEEECCEEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEE ALMESRD EEECCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]