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The map label for this gene is apeB [H]

Identifier: 108801513

GI number: 108801513

Start: 4825692

End: 4826951

Strand: Reverse

Name: apeB [H]

Synonym: Mmcs_4550

Alternate gene names: 108801513

Gene position: 4826951-4825692 (Counterclockwise)

Preceding gene: 108801514

Following gene: 108801512

Centisome position: 84.6

GC content: 68.49

Gene sequence:

>1260_bases
ATGCCAGCCAGCCCCCAGAGCCTGTGCGCCTTCATCGATGCCTCGCCGTCCCCGTTCCATGTGTGCGGCACCGTCGCGGA
CCGACTGCGCGACGCCGGCTTCACCGAACTCGCCGAAGGCGACGCGTGGCCGTCGGCGGCCGGTGACTACTTCACGGTGC
GGGCCGGCTCACTGGTGGCGTGGCGGGCCGGTGAGAACCCCCATGCCCCGTTCCGCATCGTCGGCGGCCATACGGACAGC
CCGAACCTGCGCGTCAAACAACACCCGGACCGGTTCGTATCCGGTTGGCGCATCGTGGCTTTGCAGCCCTACGGCGGTGC
GTGGCTGAACTCCTGGCTGGACCGGGATCTCGGGATCAGCGGCAGACTGTCGATCCGGGCGGGTGACTCGCTCGAACACC
GGCTGATCCGCATCGACGAACCGATTCTGCGGGTGCCGCAGCTGGCGATCCACCTCTCCGAAGACCGCAAGGGCGTCAGC
CTCGACCCGCAGCGTCACGTGAACGCGGTGTGGGGGGTGGGTGGTTCGGCTCGTTCGTTCCTGGGCTACATCGCTGACCG
GGCGGGGGTCGCCGAGGATGCCGTGCTCGCCGCGGATCTCATGACCCATGATCTGGCGCCGTCGACGTTGGTCGGCGCGG
ACCGCGAACTGGTCAGTGCGCCAAGGCTGGACAATCAGGCGACGTGTTATGCGGGCCTGGAGGCGCTGTTGGCGGCGCAG
CCTCGCGATGTGGTGCCGGTGTTGGCGCTCTTCGACCACGAGGAGGTCGGATCCACGTCCGATCACGGGGCTCAATCAGA
GCTGCTGCCAACGGTTTTGGAGAGAATCACGCTGGCGGCCGGCGGACACCGTGAGGATTTGCTGCGACGGATGTCCGGCT
CGGTGGTGGCATCGGGCGACATGGCGCACGCGACTCATCCCAACTACCCGGAGCGCCACGAACCCGGCCACCTCATCGAG
GTGAACGCCGGGCCGGTGCTCAAGGTGCAGCCGAACCTGCGTTACGCCACGGACGGACGCACCGCTGCGACGTTCGCGCT
GGCGTGTGCGCAGGCCGGGGTGCCGATGCAACGCTACGAACATCGGGCCGACCTGCCGTGCGGGTCCACGATCGGGCCGA
TGACGTCGGCGCGCACCGGGATTCCCACCGTGGACGTCGGCGCCGCGCAGTTGGCCATGCATTCCGCGCGCGAAGTCATG
GGTGCCGATGATGTCGCGGCGTACTCCGCGGCGCTGCAGGCGTTCTTGTCACCGGCCTGA

Upstream 100 bases:

>100_bases
AAGGCGCGATGGCCCGTGCCGACGATGCCGACTGAACGCCGAGTCGGGCGGGAATCGACCCTGACGCACGTTCGATCGGT
TCGACCGTCAAGATGAAGAG

Downstream 100 bases:

>100_bases
TTTATCGTCGGCTCCATGGCGATGACCGTGGAGATGATCACGTTCGACTGCACCGATCCCGACGCGCTGGCCCAGTGGTG
GGCGGAGGCGGTCGGCGGCG

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MPASPQSLCAFIDASPSPFHVCGTVADRLRDAGFTELAEGDAWPSAAGDYFTVRAGSLVAWRAGENPHAPFRIVGGHTDS
PNLRVKQHPDRFVSGWRIVALQPYGGAWLNSWLDRDLGISGRLSIRAGDSLEHRLIRIDEPILRVPQLAIHLSEDRKGVS
LDPQRHVNAVWGVGGSARSFLGYIADRAGVAEDAVLAADLMTHDLAPSTLVGADRELVSAPRLDNQATCYAGLEALLAAQ
PRDVVPVLALFDHEEVGSTSDHGAQSELLPTVLERITLAAGGHREDLLRRMSGSVVASGDMAHATHPNYPERHEPGHLIE
VNAGPVLKVQPNLRYATDGRTAATFALACAQAGVPMQRYEHRADLPCGSTIGPMTSARTGIPTVDVGAAQLAMHSAREVM
GADDVAAYSAALQAFLSPA

Sequences:

>Translated_419_residues
MPASPQSLCAFIDASPSPFHVCGTVADRLRDAGFTELAEGDAWPSAAGDYFTVRAGSLVAWRAGENPHAPFRIVGGHTDS
PNLRVKQHPDRFVSGWRIVALQPYGGAWLNSWLDRDLGISGRLSIRAGDSLEHRLIRIDEPILRVPQLAIHLSEDRKGVS
LDPQRHVNAVWGVGGSARSFLGYIADRAGVAEDAVLAADLMTHDLAPSTLVGADRELVSAPRLDNQATCYAGLEALLAAQ
PRDVVPVLALFDHEEVGSTSDHGAQSELLPTVLERITLAAGGHREDLLRRMSGSVVASGDMAHATHPNYPERHEPGHLIE
VNAGPVLKVQPNLRYATDGRTAATFALACAQAGVPMQRYEHRADLPCGSTIGPMTSARTGIPTVDVGAAQLAMHSAREVM
GADDVAAYSAALQAFLSPA
>Mature_418_residues
PASPQSLCAFIDASPSPFHVCGTVADRLRDAGFTELAEGDAWPSAAGDYFTVRAGSLVAWRAGENPHAPFRIVGGHTDSP
NLRVKQHPDRFVSGWRIVALQPYGGAWLNSWLDRDLGISGRLSIRAGDSLEHRLIRIDEPILRVPQLAIHLSEDRKGVSL
DPQRHVNAVWGVGGSARSFLGYIADRAGVAEDAVLAADLMTHDLAPSTLVGADRELVSAPRLDNQATCYAGLEALLAAQP
RDVVPVLALFDHEEVGSTSDHGAQSELLPTVLERITLAAGGHREDLLRRMSGSVVASGDMAHATHPNYPERHEPGHLIEV
NAGPVLKVQPNLRYATDGRTAATFALACAQAGVPMQRYEHRADLPCGSTIGPMTSARTGIPTVDVGAAQLAMHSAREVMG
ADDVAAYSAALQAFLSPA

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=447, Percent_Identity=34.2281879194631, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17552916, Length=443, Percent_Identity=37.020316027088, Blast_Score=249, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6321905, Length=462, Percent_Identity=32.9004329004329, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6322746, Length=452, Percent_Identity=30.0884955752212, Blast_Score=193, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 44582; Mature: 44450

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASPQSLCAFIDASPSPFHVCGTVADRLRDAGFTELAEGDAWPSAAGDYFTVRAGSLVA
CCCCHHHHEEEECCCCCCEEHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEECCCEEE
WRAGENPHAPFRIVGGHTDSPNLRVKQHPDRFVSGWRIVALQPYGGAWLNSWLDRDLGIS
EECCCCCCCCEEEECCCCCCCCCEEECCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCCC
GRLSIRAGDSLEHRLIRIDEPILRVPQLAIHLSEDRKGVSLDPQRHVNAVWGVGGSARSF
CEEEEECCCCHHHHEEECCCHHHHCCCEEEEECCCCCCCCCCHHHHCHHHCCCCCHHHHH
LGYIADRAGVAEDAVLAADLMTHDLAPSTLVGADRELVSAPRLDNQATCYAGLEALLAAQ
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHCC
PRDVVPVLALFDHEEVGSTSDHGAQSELLPTVLERITLAAGGHREDLLRRMSGSVVASGD
CCCHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCC
MAHATHPNYPERHEPGHLIEVNAGPVLKVQPNLRYATDGRTAATFALACAQAGVPMQRYE
CCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCEEECCCCHHHHHHHHHHHCCCCHHHHH
HRADLPCGSTIGPMTSARTGIPTVDVGAAQLAMHSAREVMGADDVAAYSAALQAFLSPA
HHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PASPQSLCAFIDASPSPFHVCGTVADRLRDAGFTELAEGDAWPSAAGDYFTVRAGSLVA
CCCHHHHEEEECCCCCCEEHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEECCCEEE
WRAGENPHAPFRIVGGHTDSPNLRVKQHPDRFVSGWRIVALQPYGGAWLNSWLDRDLGIS
EECCCCCCCCEEEECCCCCCCCCEEECCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCCC
GRLSIRAGDSLEHRLIRIDEPILRVPQLAIHLSEDRKGVSLDPQRHVNAVWGVGGSARSF
CEEEEECCCCHHHHEEECCCHHHHCCCEEEEECCCCCCCCCCHHHHCHHHCCCCCHHHHH
LGYIADRAGVAEDAVLAADLMTHDLAPSTLVGADRELVSAPRLDNQATCYAGLEALLAAQ
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHCC
PRDVVPVLALFDHEEVGSTSDHGAQSELLPTVLERITLAAGGHREDLLRRMSGSVVASGD
CCCHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCC
MAHATHPNYPERHEPGHLIEVNAGPVLKVQPNLRYATDGRTAATFALACAQAGVPMQRYE
CCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCEEECCCCHHHHHHHHHHHCCCCHHHHH
HRADLPCGSTIGPMTSARTGIPTVDVGAAQLAMHSAREVMGADDVAAYSAALQAFLSPA
HHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]