Click here to switch to the map view.

The map label for this gene is walR [H]

Identifier: 108801478

GI number: 108801478

Start: 4793316

End: 4794059

Strand: Reverse

Name: walR [H]

Synonym: Mmcs_4515

Alternate gene names: 108801478

Gene position: 4794059-4793316 (Counterclockwise)

Preceding gene: 108801479

Following gene: 108801472

Centisome position: 84.03

GC content: 71.91

Gene sequence:

>744_bases
GTGACGCTCGAGGTGAGGCGCACCGACCCGCCGTCCGGCGTGAGTGAGCGCCGGCCGGCCGTGCCGCCGGTGTGGGGGAC
CCTGATGCTGGTCGACCCGGACGCCGACATCGCCGGGCGGCTGATGGATGGCGCGGCCGCGGTCGGCATCGAGACAACAT
GGTGCGACGACGGCGTCGAAGCGCTCCTGGCGATCGGGGTGAACCCGCCGGATGTGCTGGTGCTCGCCGCGCGCACCCGC
ACCGTCGACGCGGCCCGGATCACCGCTGCGGTACGCAGCAGGTGGGACCTACCCATCCTGATCGGCTCGACCACCGCCGA
TGACGGCACCCGGCAGGCGCTGACCTCGGGGGCGTCGGCGTTGATCGTGCGCCCCTACGACGTCGCCGCGATCGCGCCGT
TCGCGCGCAGCGCCGCTCACCGGCCGGAGCCGACAGGTGCCCGGTACGCGGCGGGCCCGATCGAGGTGAACCGGGACGGG
TACGAGACCAGGGTGCGGGGGCGCGACGTGCAGTTGACCCAGCGCGAACTCGAATTGCTCGTCTACCTGATCGAACGCCA
CGGTCGGGTCGCCAGCAGCGACGAGATCAGCCGGGCGGTCTGGGGACATCCCGCCGACACCAACACCGTCGCGGTCCACG
TACGCCGGCTCCGGGAGAAACTCGGGCACGATCCCCAACACGGTGAGTTCATCCGCACCATCCGCGGCGCGGGATACCGG
CTCGCGCCGTCCATCTACACGTAG

Upstream 100 bases:

>100_bases
TGGAGGTCGACGACACGGAGAAGATCTTCTCCAATCCGACGCAGAAGGCCACGGAGGACTACATCTCGGGCCGCTTCGGC
TGACGTGTGGGTGGTCGCGG

Downstream 100 bases:

>100_bases
GGCGGCCGGCGAGTTCTCCCGCTCGCGCGGGAAGGCGGCTCAGCGTGGTGTCGGGATGACCTCTTCGGTCGGGTACGCAC
CGGTGACCTGGAAGATGACC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTLEVRRTDPPSGVSERRPAVPPVWGTLMLVDPDADIAGRLMDGAAAVGIETTWCDDGVEALLAIGVNPPDVLVLAARTR
TVDAARITAAVRSRWDLPILIGSTTADDGTRQALTSGASALIVRPYDVAAIAPFARSAAHRPEPTGARYAAGPIEVNRDG
YETRVRGRDVQLTQRELELLVYLIERHGRVASSDEISRAVWGHPADTNTVAVHVRRLREKLGHDPQHGEFIRTIRGAGYR
LAPSIYT

Sequences:

>Translated_247_residues
MTLEVRRTDPPSGVSERRPAVPPVWGTLMLVDPDADIAGRLMDGAAAVGIETTWCDDGVEALLAIGVNPPDVLVLAARTR
TVDAARITAAVRSRWDLPILIGSTTADDGTRQALTSGASALIVRPYDVAAIAPFARSAAHRPEPTGARYAAGPIEVNRDG
YETRVRGRDVQLTQRELELLVYLIERHGRVASSDEISRAVWGHPADTNTVAVHVRRLREKLGHDPQHGEFIRTIRGAGYR
LAPSIYT
>Mature_246_residues
TLEVRRTDPPSGVSERRPAVPPVWGTLMLVDPDADIAGRLMDGAAAVGIETTWCDDGVEALLAIGVNPPDVLVLAARTRT
VDAARITAAVRSRWDLPILIGSTTADDGTRQALTSGASALIVRPYDVAAIAPFARSAAHRPEPTGARYAAGPIEVNRDGY
ETRVRGRDVQLTQRELELLVYLIERHGRVASSDEISRAVWGHPADTNTVAVHVRRLREKLGHDPQHGEFIRTIRGAGYRL
APSIYT

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=219, Percent_Identity=23.2876712328767, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082012, Length=171, Percent_Identity=30.4093567251462, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=24.5454545454545, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26763; Mature: 26631

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLEVRRTDPPSGVSERRPAVPPVWGTLMLVDPDADIAGRLMDGAAAVGIETTWCDDGVE
CEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCEEECEEEECCCHHHH
ALLAIGVNPPDVLVLAARTRTVDAARITAAVRSRWDLPILIGSTTADDGTRQALTSGASA
HHEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCCCE
LIVRPYDVAAIAPFARSAAHRPEPTGARYAAGPIEVNRDGYETRVRGRDVQLTQRELELL
EEECCCCHHHHHHHHHHHCCCCCCCCCCEECCCEEECCCCCEEEECCCCCCHHHHHHHHH
VYLIERHGRVASSDEISRAVWGHPADTNTVAVHVRRLREKLGHDPQHGEFIRTIRGAGYR
HHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEE
LAPSIYT
ECCCCCC
>Mature Secondary Structure 
TLEVRRTDPPSGVSERRPAVPPVWGTLMLVDPDADIAGRLMDGAAAVGIETTWCDDGVE
EEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCEEECEEEECCCHHHH
ALLAIGVNPPDVLVLAARTRTVDAARITAAVRSRWDLPILIGSTTADDGTRQALTSGASA
HHEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCCCE
LIVRPYDVAAIAPFARSAAHRPEPTGARYAAGPIEVNRDGYETRVRGRDVQLTQRELELL
EEECCCCHHHHHHHHHHHCCCCCCCCCCEECCCEEECCCCCEEEECCCCCCHHHHHHHHH
VYLIERHGRVASSDEISRAVWGHPADTNTVAVHVRRLREKLGHDPQHGEFIRTIRGAGYR
HHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEE
LAPSIYT
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA