Click here to switch to the map view.

The map label for this gene is moaC [H]

Identifier: 108801445

GI number: 108801445

Start: 4759965

End: 4760450

Strand: Reverse

Name: moaC [H]

Synonym: Mmcs_4482

Alternate gene names: 108801445

Gene position: 4760450-4759965 (Counterclockwise)

Preceding gene: 108801446

Following gene: 108801444

Centisome position: 83.44

GC content: 71.19

Gene sequence:

>486_bases
GTGGCCGCGAGCTCGCAGCACGGGCTTTCGCACGTCGACGAGTCCGGCGCGGCGCACATGGTCGACGTCAGCGGTAAGGA
CGTCACCAAACGCACCGCCGTCGCGGCGGGCACGCTGCACACCCGCCCCGACGTGGTCGCGCTGATCGCGTCCGGCGGGC
TGCCCAAGGGCGACGCGCTGGCGACCGCGCGGGTCGCCGGCATCATGGCCGCCAAACGCACCAGCGATCTGATCCCGCTG
TGCCATCAGCTCGCGCTGACCGGTGTGGACGTCGACTTCGAGATCGGCGAGAGCCACGTCCGCGTCACCGCGACCGTGCG
GACCACCGACCGCACCGGGGTGGAGATGGAAGCGCTGACGGCGGTGAGCGTGGCCGCGCTGACCGTCTACGACATGATCA
AGGCCGTCGACCCCGCCGCCCGCATCGACGACATCGCGGTGCTTCGTAAAGAGGGCGGCAAGACCGGCACCTGGACGCGG
CCGTGA

Upstream 100 bases:

>100_bases
CGACCGCGTCGGCGCCCTCTCGCCGTTCGGCGACCTGACCTTCCCGCTGCCAGCCGACGAGCTGCCGTACCTGCATCCCG
TCACCGTCGTCAACAGGTAA

Downstream 100 bases:

>100_bases
CCGGCCGCACCGGCCGCGTCGTCATCGCCTCCACCCGGGCCGCCGCAGCGGTCTACGAGGACCGGACCGGACCCCCGATC
GTCGAGTGGTTGACCGGCCG

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MAASSQHGLSHVDESGAAHMVDVSGKDVTKRTAVAAGTLHTRPDVVALIASGGLPKGDALATARVAGIMAAKRTSDLIPL
CHQLALTGVDVDFEIGESHVRVTATVRTTDRTGVEMEALTAVSVAALTVYDMIKAVDPAARIDDIAVLRKEGGKTGTWTR
P

Sequences:

>Translated_161_residues
MAASSQHGLSHVDESGAAHMVDVSGKDVTKRTAVAAGTLHTRPDVVALIASGGLPKGDALATARVAGIMAAKRTSDLIPL
CHQLALTGVDVDFEIGESHVRVTATVRTTDRTGVEMEALTAVSVAALTVYDMIKAVDPAARIDDIAVLRKEGGKTGTWTR
P
>Mature_160_residues
AASSQHGLSHVDESGAAHMVDVSGKDVTKRTAVAAGTLHTRPDVVALIASGGLPKGDALATARVAGIMAAKRTSDLIPLC
HQLALTGVDVDFEIGESHVRVTATVRTTDRTGVEMEALTAVSVAALTVYDMIKAVDPAARIDDIAVLRKEGGKTGTWTRP

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=152, Percent_Identity=51.9736842105263, Blast_Score=142, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32566331, Length=159, Percent_Identity=45.2830188679245, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28574490, Length=156, Percent_Identity=50.6410256410256, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=52.5547445255474, Blast_Score=127, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16680; Mature: 16549

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASSQHGLSHVDESGAAHMVDVSGKDVTKRTAVAAGTLHTRPDVVALIASGGLPKGDAL
CCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHEECCCCCCCCEEEEEECCCCCCCCHH
ATARVAGIMAAKRTSDLIPLCHQLALTGVDVDFEIGESHVRVTATVRTTDRTGVEMEALT
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCEEEEEEEEEECCCCCCCHHHHH
AVSVAALTVYDMIKAVDPAARIDDIAVLRKEGGKTGTWTRP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AASSQHGLSHVDESGAAHMVDVSGKDVTKRTAVAAGTLHTRPDVVALIASGGLPKGDAL
CCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHEECCCCCCCCEEEEEECCCCCCCCHH
ATARVAGIMAAKRTSDLIPLCHQLALTGVDVDFEIGESHVRVTATVRTTDRTGVEMEALT
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCEEEEEEEEEECCCCCCCHHHHH
AVSVAALTVYDMIKAVDPAARIDDIAVLRKEGGKTGTWTRP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]