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The map label for this gene is cobF [H]

Identifier: 108801302

GI number: 108801302

Start: 4614420

End: 4615184

Strand: Reverse

Name: cobF [H]

Synonym: Mmcs_4338

Alternate gene names: 108801302

Gene position: 4615184-4614420 (Counterclockwise)

Preceding gene: 108801303

Following gene: 108801301

Centisome position: 80.89

GC content: 69.54

Gene sequence:

>765_bases
GTGACTCGACGGATCCACGTCATCGGCATCGGTGCGGGTGACCCGGACTACGTGACCGCCCAGGCCGTCGCGGCACTCAA
CGACACCGACGTGTTCTTCGCGATGGACAAGGGGTCCCGCACGCGAGGAGGACAACAGGCGGATACGAAGGACGACCTGG
TCGCATTGCGCCGGCTGATCTGCGAACGGTTCATCACCGAACCCGGCTACCGGTTCGTCGAGATGCCCGACCCCGTGCGG
GCCAAGAGCGGCGACTATCGCCAGGCCGTCGACGAGTGGCACGCCGCGCGGGCGCGGTTGTGGGCCGAGGCGATCGAACG
CGAACTCGACGACGACGGGGTCGGCGCCTTCCTCGCCTGGGGTGACCCGTCGCTGTATGACAGCACGCTGCGGATCCTCG
ACCGGGTCGCCGCCCACGTCGACATCGACTACGACGTCATCCCGGGCGTCACCGCCATCCAGGCACTCACCGCACGGCAC
CGGATCCCGCTCAACGACGTCGGCGAACCCGTGCTCATCACCACCGGACGGCGGCTGCGCGAACAGGGCCTGACCGGGAC
CGCGGTGGTGATGCTCGACGCCGACTGCGCATTCACCGGGACGCCCGCGCAGACCCGGATCTGGTGGGGCGCCTACCTCG
GCACCGCCGACGAACTGCTCGTCTCCGGGACCGTCGGCGAGGTGGGTGAGCGGATCGTCGCGCTGCGCGCCGAGGCGCGG
GAGCGGCACGGCTGGATCATGGACACCTACCTGCTTCGTCCCTGA

Upstream 100 bases:

>100_bases
GGAAGCCGCCATCGAAGAGGACGTCGAACGCGCGAAGGCGCTGCGACGCAGCCGGGGCCGCGACGACGGGTGACCCACGC
ACCCGGGCATACTCACCTGC

Downstream 100 bases:

>100_bases
GCGTGCGAAGATCAGCCCGTGGGTTTCCTGCTCCGGGCCGCGGTCACCGGGGTCGCGCTGTGGCTTGTCACGCAATTTGT
CTCCGGCATGGAGTTCGTCG

Product: precorrin 6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTRRIHVIGIGAGDPDYVTAQAVAALNDTDVFFAMDKGSRTRGGQQADTKDDLVALRRLICERFITEPGYRFVEMPDPVR
AKSGDYRQAVDEWHAARARLWAEAIERELDDDGVGAFLAWGDPSLYDSTLRILDRVAAHVDIDYDVIPGVTAIQALTARH
RIPLNDVGEPVLITTGRRLREQGLTGTAVVMLDADCAFTGTPAQTRIWWGAYLGTADELLVSGTVGEVGERIVALRAEAR
ERHGWIMDTYLLRP

Sequences:

>Translated_254_residues
MTRRIHVIGIGAGDPDYVTAQAVAALNDTDVFFAMDKGSRTRGGQQADTKDDLVALRRLICERFITEPGYRFVEMPDPVR
AKSGDYRQAVDEWHAARARLWAEAIERELDDDGVGAFLAWGDPSLYDSTLRILDRVAAHVDIDYDVIPGVTAIQALTARH
RIPLNDVGEPVLITTGRRLREQGLTGTAVVMLDADCAFTGTPAQTRIWWGAYLGTADELLVSGTVGEVGERIVALRAEAR
ERHGWIMDTYLLRP
>Mature_253_residues
TRRIHVIGIGAGDPDYVTAQAVAALNDTDVFFAMDKGSRTRGGQQADTKDDLVALRRLICERFITEPGYRFVEMPDPVRA
KSGDYRQAVDEWHAARARLWAEAIERELDDDGVGAFLAWGDPSLYDSTLRILDRVAAHVDIDYDVIPGVTAIQALTARHR
IPLNDVGEPVLITTGRRLREQGLTGTAVVMLDADCAFTGTPAQTRIWWGAYLGTADELLVSGTVGEVGERIVALRAEARE
RHGWIMDTYLLRP

Specific function: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012797 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.152 [H]

Molecular weight: Translated: 28076; Mature: 27945

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRIHVIGIGAGDPDYVTAQAVAALNDTDVFFAMDKGSRTRGGQQADTKDDLVALRRLI
CCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
CERFITEPGYRFVEMPDPVRAKSGDYRQAVDEWHAARARLWAEAIERELDDDGVGAFLAW
HHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GDPSLYDSTLRILDRVAAHVDIDYDVIPGVTAIQALTARHRIPLNDVGEPVLITTGRRLR
CCCHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHCCCCCCCCCCCEEEECCHHHH
EQGLTGTAVVMLDADCAFTGTPAQTRIWWGAYLGTADELLVSGTVGEVGERIVALRAEAR
HCCCCCEEEEEEECCCCCCCCCCCCEEEEEHHHCCHHHHEEECCHHHHHHHHHHHHHHHH
ERHGWIMDTYLLRP
HHCCEEEEEEEECC
>Mature Secondary Structure 
TRRIHVIGIGAGDPDYVTAQAVAALNDTDVFFAMDKGSRTRGGQQADTKDDLVALRRLI
CCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
CERFITEPGYRFVEMPDPVRAKSGDYRQAVDEWHAARARLWAEAIERELDDDGVGAFLAW
HHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GDPSLYDSTLRILDRVAAHVDIDYDVIPGVTAIQALTARHRIPLNDVGEPVLITTGRRLR
CCCHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHCCCCCCCCCCCEEEECCHHHH
EQGLTGTAVVMLDADCAFTGTPAQTRIWWGAYLGTADELLVSGTVGEVGERIVALRAEAR
HCCCCCEEEEEEECCCCCCCCCCCCEEEEEHHHCCHHHHEEECCHHHHHHHHHHHHHHHH
ERHGWIMDTYLLRP
HHCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]