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The map label for this gene is ydfG [C]

Identifier: 108801299

GI number: 108801299

Start: 4612309

End: 4613058

Strand: Reverse

Name: ydfG [C]

Synonym: Mmcs_4335

Alternate gene names: 108801299

Gene position: 4613058-4612309 (Counterclockwise)

Preceding gene: 108801300

Following gene: 108801297

Centisome position: 80.85

GC content: 68.93

Gene sequence:

>750_bases
ATGACCCGTCAGAGGATCCTGATCACCGGCGCGAGCTCCGGGCTGGGCGCCGGGATGGCCCGCGCGTTCGCCGCCAAGGG
GCGTGACCTGGCGCTGTGCGCCCGCCGCGTCGACCGCCTCGACGAACTCAAAGCCGAACTGAAGCAACGGTATCCGGAGA
TCACCGTCGCAGTGGCCGAACTCGACGTCAACGACCACGACCAGGTGCCGAAGGTGTTCGCCGCGCTGTCCGACGAACTC
GGCGGCCTCGACCGTGTGATCGTCAACGCCGGTCTCGGCAAGGGCGCACCGCTCGGGTCGGGCAAGCTGTGGGCCAACAA
GGCGACCATCGAGACCAACCTCGTCGCGGCGCTCGTGCAGATCGAGACGGCGCTGGAGATGTTCAAGCGCACCGGTGCCG
GACACCTCGTGCTGATCTCGTCGGTGCTGGGCAACAAGGGCGTGCCCGGGGTGAAGGCCGCCTACGCCGCGAGCAAGGCC
GGCGTCTCGTCGCTGGGGGAGTCGCTGCGCGCCGAATACGCCAAGGGTCCGATCCGCGTGACGGTCCTCGAACCCGGTTA
CATCGAGTCGGAGATGACCTCGAAGTCCGCGTCGACGATGCTCATGACCGACACCGATACCGGCGTCGCCGCAATGGTCC
GCGTCATCGAGAAGGAGGCCGGCCGCGCCGCCGTGCCATGGTGGCCGTGGGCGCCGCTGGTGCAGCTGATGCGGGTCCTG
CCGCCGCGGCTCACGCGACTCTTCGCGTGA

Upstream 100 bases:

>100_bases
CGTCGCCTCTCGCGGCTGCTCAAGTAATGGCGATTTCGGCGTGCGCGGTCGCGCTGGGCGCGACCCAGCACGCCGAAATC
GCCGCCGATACGCTGCCCGT

Downstream 100 bases:

>100_bases
TTTCGGCGTGCTGGGTCGCGCCTACCGCGACCCAGCACGCCGAAATCCCTCAGGCCGAGCGACCCCGCTCCGCTCGGTAG
CGGCGCACCAGCGCGTCGGT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTRQRILITGASSGLGAGMARAFAAKGRDLALCARRVDRLDELKAELKQRYPEITVAVAELDVNDHDQVPKVFAALSDEL
GGLDRVIVNAGLGKGAPLGSGKLWANKATIETNLVAALVQIETALEMFKRTGAGHLVLISSVLGNKGVPGVKAAYAASKA
GVSSLGESLRAEYAKGPIRVTVLEPGYIESEMTSKSASTMLMTDTDTGVAAMVRVIEKEAGRAAVPWWPWAPLVQLMRVL
PPRLTRLFA

Sequences:

>Translated_249_residues
MTRQRILITGASSGLGAGMARAFAAKGRDLALCARRVDRLDELKAELKQRYPEITVAVAELDVNDHDQVPKVFAALSDEL
GGLDRVIVNAGLGKGAPLGSGKLWANKATIETNLVAALVQIETALEMFKRTGAGHLVLISSVLGNKGVPGVKAAYAASKA
GVSSLGESLRAEYAKGPIRVTVLEPGYIESEMTSKSASTMLMTDTDTGVAAMVRVIEKEAGRAAVPWWPWAPLVQLMRVL
PPRLTRLFA
>Mature_248_residues
TRQRILITGASSGLGAGMARAFAAKGRDLALCARRVDRLDELKAELKQRYPEITVAVAELDVNDHDQVPKVFAALSDELG
GLDRVIVNAGLGKGAPLGSGKLWANKATIETNLVAALVQIETALEMFKRTGAGHLVLISSVLGNKGVPGVKAAYAASKAG
VSSLGESLRAEYAKGPIRVTVLEPGYIESEMTSKSASTMLMTDTDTGVAAMVRVIEKEAGRAAVPWWPWAPLVQLMRVLP
PRLTRLFA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=200, Percent_Identity=34, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=31.25, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI7657478, Length=193, Percent_Identity=31.0880829015544, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=28.494623655914, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI157739938, Length=192, Percent_Identity=28.6458333333333, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=28.1407035175879, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32455239, Length=200, Percent_Identity=27.5, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI5031765, Length=200, Percent_Identity=27.5, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4503817, Length=216, Percent_Identity=26.3888888888889, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI19743808, Length=202, Percent_Identity=27.2277227722772, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI226371731, Length=196, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=29.8913043478261, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082100, Length=220, Percent_Identity=31.3636363636364, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787335, Length=187, Percent_Identity=31.5508021390374, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786701, Length=258, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=236, Percent_Identity=27.9661016949153, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71997402, Length=193, Percent_Identity=29.0155440414508, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17570069, Length=201, Percent_Identity=29.3532338308458, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=253, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=253, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=30.9644670050761, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI116007236, Length=195, Percent_Identity=32.8205128205128, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=31.6062176165803, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI116007238, Length=185, Percent_Identity=33.5135135135135, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24641388, Length=208, Percent_Identity=31.7307692307692, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571387, Length=198, Percent_Identity=32.8282828282828, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI116007234, Length=221, Percent_Identity=31.2217194570136, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24663911, Length=199, Percent_Identity=30.1507537688442, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=30.6532663316583, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281364494, Length=198, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI116007232, Length=187, Percent_Identity=33.6898395721925, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648693, Length=195, Percent_Identity=29.7435897435897, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355889, Length=195, Percent_Identity=29.7435897435897, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644339, Length=184, Percent_Identity=32.6086956521739, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648944, Length=199, Percent_Identity=27.6381909547739, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357041, Length=191, Percent_Identity=31.413612565445, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI23397609, Length=194, Percent_Identity=31.4432989690722, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24580925, Length=205, Percent_Identity=26.3414634146341, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26447; Mature: 26316

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRQRILITGASSGLGAGMARAFAAKGRDLALCARRVDRLDELKAELKQRYPEITVAVAE
CCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
LDVNDHDQVPKVFAALSDELGGLDRVIVNAGLGKGAPLGSGKLWANKATIETNLVAALVQ
ECCCCCHHHHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCEECCCCHHHHHHHHHHHH
IETALEMFKRTGAGHLVLISSVLGNKGVPGVKAAYAASKAGVSSLGESLRAEYAKGPIRV
HHHHHHHHHHCCCCCEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TVLEPGYIESEMTSKSASTMLMTDTDTGVAAMVRVIEKEAGRAAVPWWPWAPLVQLMRVL
EEECCCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
PPRLTRLFA
CHHHHHHCC
>Mature Secondary Structure 
TRQRILITGASSGLGAGMARAFAAKGRDLALCARRVDRLDELKAELKQRYPEITVAVAE
CCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
LDVNDHDQVPKVFAALSDELGGLDRVIVNAGLGKGAPLGSGKLWANKATIETNLVAALVQ
ECCCCCHHHHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCEECCCCHHHHHHHHHHHH
IETALEMFKRTGAGHLVLISSVLGNKGVPGVKAAYAASKAGVSSLGESLRAEYAKGPIRV
HHHHHHHHHHCCCCCEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TVLEPGYIESEMTSKSASTMLMTDTDTGVAAMVRVIEKEAGRAAVPWWPWAPLVQLMRVL
EEECCCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
PPRLTRLFA
CHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]