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The map label for this gene is engD [H]

Identifier: 108801066

GI number: 108801066

Start: 4370380

End: 4371510

Strand: Reverse

Name: engD [H]

Synonym: Mmcs_4102

Alternate gene names: 108801066

Gene position: 4371510-4370380 (Counterclockwise)

Preceding gene: 108801068

Following gene: 108801065

Centisome position: 76.62

GC content: 65.52

Gene sequence:

>1131_bases
GTGCCCGCCGGACTCTGGCAGACTGTCATCCCTGTGGGGCTCAACCTGGGAATCGTCGGACTGCCGAATGTCGGTAAGTC
GACCCTGTTCAACGCGCTGACGCGCAACAACGTGCTCGCCGCGAACTACCCGTTCGCGACGATCGAGCCCAACGAAGGTG
TGGTCGCGCTGCCGGACCCCCGGCTCGAGGCGCTCGCGAAGATCTTTCATTCCGAGAAGATTGTGCCTGCGCCGGTGACG
TTCGTCGACATCGCCGGCATCGTCAAGGGCGCCTCGGAGGGGGCGGGACTGGGCAACAAGTTCCTCGCCAACATCCGCGA
ATGTGATGCGATCTGCCAGGTCGTGCGCGTCTTCGCCGACGACGACGTCGTCCACGTCGACGGCAAGGTGGACCCGAAAT
CCGATATCGAGGTGATCGAGACCGAGCTGATCCTCGCCGACATGCAGACGTTGGAGAGGGCCGTGCCGCGGCTCGAGAAG
GAAGCCCGCACCCACAAGGACCGCAAACCCGTCCTCGACGCGGCCCTCGCCGCGCAGGAGGTGCTCAATTCGGGCAAGAC
GCTGTTCGCGGCCGGTACCGACGTCAGCCTGCTGCGTGAGCTGAACTTGATGACCACCAAACCGTTCCTCTACGTGTTCA
ACGCCGACGAGTCGGTGCTGACCGATGAGGCGCGCAAGGCGGAGCTGCGGGAGCTCGTTGCGCCCGCCGACTGTGTGTTC
CTCGACGCGAAGATCGAGGCGGAACTGCAGGAGCTCGACGACGAGTCGGCCGCCGAGCTGCTCGAGTCGATCGGGCAGAC
CGAGCGCGGTCTGGACGCGCTGGCGCGGGCCGGGTTTCACACGTTGAGACTGCAGACCTACCTCACCGCGGGCCCGAAGG
AGGCGCGCGCCTGGACGATCCACCAGGGCGACACCGCACCGAAGGCCGCGGGCGTGATCCACAGCGACTTCGAGAAGGGC
TTCATCAAAGCCGAGATCGTCTCGTTCGACGATCTGGCCGAGGCAGGCTCGATGGCCGCGGCGAAGGCGGCCGGCAAGGT
CCGCATGGAGGGCAAGGACTACGTGATGGCCGACGGCGACGTGGTGGAGTTCCGCCATGGACAACCATCTACGTCGAAAG
CCAAGGCTTAG

Upstream 100 bases:

>100_bases
CAGAGCGGTGGTCGGCCGGTACTGCCGACCGTGCGCGCTGTCCGGACACAGGTAGACCGTACCGGCTGATCCGGAGTGTG
CGCGCCCAGCGCGCGCGGGC

Downstream 100 bases:

>100_bases
CGCGGTATCCCCGACTACGTCGACACCCGGAGGCGCGGATGGCGAGAGTTCCCGAGATCACCGCGATCCTCGGCGGTAGC
CGCTTCACGCGTTTGGATGT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MPAGLWQTVIPVGLNLGIVGLPNVGKSTLFNALTRNNVLAANYPFATIEPNEGVVALPDPRLEALAKIFHSEKIVPAPVT
FVDIAGIVKGASEGAGLGNKFLANIRECDAICQVVRVFADDDVVHVDGKVDPKSDIEVIETELILADMQTLERAVPRLEK
EARTHKDRKPVLDAALAAQEVLNSGKTLFAAGTDVSLLRELNLMTTKPFLYVFNADESVLTDEARKAELRELVAPADCVF
LDAKIEAELQELDDESAAELLESIGQTERGLDALARAGFHTLRLQTYLTAGPKEARAWTIHQGDTAPKAAGVIHSDFEKG
FIKAEIVSFDDLAEAGSMAAAKAAGKVRMEGKDYVMADGDVVEFRHGQPSTSKAKA

Sequences:

>Translated_376_residues
MPAGLWQTVIPVGLNLGIVGLPNVGKSTLFNALTRNNVLAANYPFATIEPNEGVVALPDPRLEALAKIFHSEKIVPAPVT
FVDIAGIVKGASEGAGLGNKFLANIRECDAICQVVRVFADDDVVHVDGKVDPKSDIEVIETELILADMQTLERAVPRLEK
EARTHKDRKPVLDAALAAQEVLNSGKTLFAAGTDVSLLRELNLMTTKPFLYVFNADESVLTDEARKAELRELVAPADCVF
LDAKIEAELQELDDESAAELLESIGQTERGLDALARAGFHTLRLQTYLTAGPKEARAWTIHQGDTAPKAAGVIHSDFEKG
FIKAEIVSFDDLAEAGSMAAAKAAGKVRMEGKDYVMADGDVVEFRHGQPSTSKAKA
>Mature_375_residues
PAGLWQTVIPVGLNLGIVGLPNVGKSTLFNALTRNNVLAANYPFATIEPNEGVVALPDPRLEALAKIFHSEKIVPAPVTF
VDIAGIVKGASEGAGLGNKFLANIRECDAICQVVRVFADDDVVHVDGKVDPKSDIEVIETELILADMQTLERAVPRLEKE
ARTHKDRKPVLDAALAAQEVLNSGKTLFAAGTDVSLLRELNLMTTKPFLYVFNADESVLTDEARKAELRELVAPADCVFL
DAKIEAELQELDDESAAELLESIGQTERGLDALARAGFHTLRLQTYLTAGPKEARAWTIHQGDTAPKAAGVIHSDFEKGF
IKAEIVSFDDLAEAGSMAAAKAAGKVRMEGKDYVMADGDVVEFRHGQPSTSKAKA

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=375, Percent_Identity=41.6, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI58761502, Length=188, Percent_Identity=38.8297872340425, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI24308117, Length=127, Percent_Identity=33.0708661417323, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787454, Length=359, Percent_Identity=50.4178272980501, Blast_Score=347, Evalue=7e-97,
Organism=Escherichia coli, GI1789574, Length=129, Percent_Identity=31.7829457364341, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=373, Percent_Identity=38.3378016085791, Blast_Score=258, Evalue=4e-69,
Organism=Saccharomyces cerevisiae, GI6319499, Length=372, Percent_Identity=39.7849462365591, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6321773, Length=380, Percent_Identity=35.7894736842105, Blast_Score=216, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6321649, Length=180, Percent_Identity=34.4444444444444, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640873, Length=368, Percent_Identity=40.4891304347826, Blast_Score=272, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24640877, Length=368, Percent_Identity=40.4891304347826, Blast_Score=272, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24640875, Length=368, Percent_Identity=40.4891304347826, Blast_Score=272, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24640879, Length=323, Percent_Identity=38.0804953560372, Blast_Score=218, Evalue=8e-57,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40407; Mature: 40276

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAGLWQTVIPVGLNLGIVGLPNVGKSTLFNALTRNNVLAANYPFATIEPNEGVVALPDP
CCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHCCCEEEECCCEEEECCCCCEEECCCH
RLEALAKIFHSEKIVPAPVTFVDIAGIVKGASEGAGLGNKFLANIRECDAICQVVRVFAD
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DDVVHVDGKVDPKSDIEVIETELILADMQTLERAVPRLEKEARTHKDRKPVLDAALAAQE
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VLNSGKTLFAAGTDVSLLRELNLMTTKPFLYVFNADESVLTDEARKAELRELVAPADCVF
HHHCCCEEEEECCCHHHHHHHHHEECCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEE
LDAKIEAELQELDDESAAELLESIGQTERGLDALARAGFHTLRLQTYLTAGPKEARAWTI
EECHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCHHEEEEEEEECCCCCCCCEEEE
HQGDTAPKAAGVIHSDFEKGFIKAEIVSFDDLAEAGSMAAAKAAGKVRMEGKDYVMADGD
ECCCCCCHHHCCHHHHHHCCCEEEEEECHHHHHHHCCHHHHHHCCCEEECCCCEEEECCC
VVEFRHGQPSTSKAKA
EEEEECCCCCCCCCCC
>Mature Secondary Structure 
PAGLWQTVIPVGLNLGIVGLPNVGKSTLFNALTRNNVLAANYPFATIEPNEGVVALPDP
CCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHCCCEEEECCCEEEECCCCCEEECCCH
RLEALAKIFHSEKIVPAPVTFVDIAGIVKGASEGAGLGNKFLANIRECDAICQVVRVFAD
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DDVVHVDGKVDPKSDIEVIETELILADMQTLERAVPRLEKEARTHKDRKPVLDAALAAQE
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VLNSGKTLFAAGTDVSLLRELNLMTTKPFLYVFNADESVLTDEARKAELRELVAPADCVF
HHHCCCEEEEECCCHHHHHHHHHEECCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEE
LDAKIEAELQELDDESAAELLESIGQTERGLDALARAGFHTLRLQTYLTAGPKEARAWTI
EECHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCHHEEEEEEEECCCCCCCCEEEE
HQGDTAPKAAGVIHSDFEKGFIKAEIVSFDDLAEAGSMAAAKAAGKVRMEGKDYVMADGD
ECCCCCCHHHCCHHHHHHCCCEEEEEECHHHHHHHCCHHHHHHCCCEEECCCCEEEECCC
VVEFRHGQPSTSKAKA
EEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA