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The map label for this gene is typA [H]

Identifier: 108801004

GI number: 108801004

Start: 4313367

End: 4315268

Strand: Reverse

Name: typA [H]

Synonym: Mmcs_4040

Alternate gene names: 108801004

Gene position: 4315268-4313367 (Counterclockwise)

Preceding gene: 108801007

Following gene: 108801003

Centisome position: 75.63

GC content: 68.66

Gene sequence:

>1902_bases
GTGGATTTACCCAATGACTTCCGCAATGTCGCCATCGTCGCCCACGTCGACCACGGCAAGACGACGCTGGTCGATGCGAT
GCTGCGGCAGTCCGGTGCGCTGAGTCACCGCGGCGACGATGCCGTCGAACGCCTGATGGACTCCGGGGATCTGGAGAAGG
AAAAAGGCATCACCATCCTCGCCAAGAACACGGCGGTGCACCGTCATCACCCCGACGGCACGATGACCGTCATCAACGTG
ATCGACACCCCGGGCCACGCCGACTTCGGCGGCGAGGTCGAGCGCGGGCTGTCCATGGTCGACGGCGTGCTGCTGCTGGT
CGACGCCTCCGAGGGGCCGTTGCCGCAGACCCGCTTCGTGCTGCGCAAGGCACTGGCCGCGCACCTGCCCGTCATCCTCG
TGGTGAACAAGACCGACCGCCCCGACGCCCGGATCGCGGAGGTGGTCTCCGAGAGCCACGATCTGCTGCTCGACGTCGCC
TCCGACCTCGACGACGAGGCGCAGAAGGCCGCCGAGGAGGCGCTCGGTCTGCCGGTCCTCTACGCCTCCGGCCGCGCGGG
TATCGCGAGCACCACCGAACCCGCGAACGGTGAGAACCCCGACGGCGAGAACCTCGACCCGCTCTTCGACGTCCTGCTCG
AGCACATCCCGCCGCCGCAGGGCGATCCGGAGGCGCCGCTGCAGGCGTTGGTGACCAACCTCGACGCGTCGGCCTTCCTC
GGCCGTCTCGCGCTGATCCGTATCTACAAGGGGCGCATCCGCAAGGGTCAGCAGGTGGCCTGGATGCGTGAGGTCGACGG
CCACCCGGTCGTGACCAACGCCAAGATCACCGAACTGCTCGTCACCGTGGGCGTCGAGCGCACCGCCACCGACGAAGCCG
TCGCCGGGGACATCGTGGCCGTCGCCGGGATCCCCGAGATCATGATCGGCGACACGCTGGCCGATCCGGACCATGCGCAC
GCACTGCCGCGCATCACCGTCGACGAGCCCGCCATCTCGGTCACCATCGGCACCAACACCTCACCGCTGGCAGGCAAGGT
GTCCGGTCACAAGCTCACCGCACGAATGGTGAAGTCGCGGTTGGACTCCGAACTGGTCGGCAACGTGTCGCTGAAGGTCG
TCGACATCGGCCGGCCCGACGCCTGGGAGGTGCAGGGCCGCGGCGAGCTGGCGCTCGCGGTGCTCGTCGAGCAGATGCGC
CGCGAGGGCTTCGAGCTCACCGTCGGCAAACCGCAGGTGGTCACCCGCACGATCGACGGCAAGCTGCACGAGCCGTTCGA
GGCCCTGACGATCGACTGCCCAGAGGAGTTCGTCGGCGCGATCACCCAGCTGATGGCCGCCCGCAAGGGCCGCATGGAGG
AGATGACCAACCACGCCGCGGGCTGGGTGCGGATGGACTTCATCGTCCCGAGCCGTGGCCTGATCGGTTTCCGCACCGAC
TTCCTGACGTTGACCCGCGGCACCGGCATCGCCAACGCGGTGTTCGACGGCTACCGCCCGTGGGCGGGGGAGATCCGCGC
CCGCCACACCGGCTCGCTGGTGTCGGACCGCAGCGGCTCGGTGACGCCGTTCGCGATGATTCAGCTCTCCGACCGTGGCC
AGTTCTTCGTCGAGCCGGGCGACGACACCTACGAGGGACAGGTCGTCGGGATCAACCCGCGTGCCGAGGACCTCGACGTC
AACGTCACCCGCGAGAAGAAGCTGACCAACATGCGCAGTTCCACCGCCGACGTGATGGAGACGCTGGCCCGTCCGCTCGA
GCTCGGCCTCGAACAGGCCATGGAGTTCTGCGCCGAGGACGAATGCGTCGAGGTCACCCCCGAGGTGGTGCGGGTGCGCA
AGGTCGAGCTCGACGCCACCCTGCGGGCCCGCGCGCGCTCGCGGGCGAAGGCGCGGAACTGA

Upstream 100 bases:

>100_bases
GCCATTACATTGCCACGGCGCGATCGGGCCGCGGTGGCCTCCCTCGCGTGCCCGGCTGTGCATTTCGCGATCGAGTCACC
GCACTGCGACAATCACCGAC

Downstream 100 bases:

>100_bases
TCAAGCTTCAGCGGTCGATACTCTGAGGAGCGTGCCGACCCGTCCCCGCCGCCACCGCGTGACGTTGGGGGCGTTGGTCT
CTGCCGTCGCACTGCTGCTC

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MDLPNDFRNVAIVAHVDHGKTTLVDAMLRQSGALSHRGDDAVERLMDSGDLEKEKGITILAKNTAVHRHHPDGTMTVINV
IDTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKALAAHLPVILVVNKTDRPDARIAEVVSESHDLLLDVA
SDLDDEAQKAAEEALGLPVLYASGRAGIASTTEPANGENPDGENLDPLFDVLLEHIPPPQGDPEAPLQALVTNLDASAFL
GRLALIRIYKGRIRKGQQVAWMREVDGHPVVTNAKITELLVTVGVERTATDEAVAGDIVAVAGIPEIMIGDTLADPDHAH
ALPRITVDEPAISVTIGTNTSPLAGKVSGHKLTARMVKSRLDSELVGNVSLKVVDIGRPDAWEVQGRGELALAVLVEQMR
REGFELTVGKPQVVTRTIDGKLHEPFEALTIDCPEEFVGAITQLMAARKGRMEEMTNHAAGWVRMDFIVPSRGLIGFRTD
FLTLTRGTGIANAVFDGYRPWAGEIRARHTGSLVSDRSGSVTPFAMIQLSDRGQFFVEPGDDTYEGQVVGINPRAEDLDV
NVTREKKLTNMRSSTADVMETLARPLELGLEQAMEFCAEDECVEVTPEVVRVRKVELDATLRARARSRAKARN

Sequences:

>Translated_633_residues
MDLPNDFRNVAIVAHVDHGKTTLVDAMLRQSGALSHRGDDAVERLMDSGDLEKEKGITILAKNTAVHRHHPDGTMTVINV
IDTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKALAAHLPVILVVNKTDRPDARIAEVVSESHDLLLDVA
SDLDDEAQKAAEEALGLPVLYASGRAGIASTTEPANGENPDGENLDPLFDVLLEHIPPPQGDPEAPLQALVTNLDASAFL
GRLALIRIYKGRIRKGQQVAWMREVDGHPVVTNAKITELLVTVGVERTATDEAVAGDIVAVAGIPEIMIGDTLADPDHAH
ALPRITVDEPAISVTIGTNTSPLAGKVSGHKLTARMVKSRLDSELVGNVSLKVVDIGRPDAWEVQGRGELALAVLVEQMR
REGFELTVGKPQVVTRTIDGKLHEPFEALTIDCPEEFVGAITQLMAARKGRMEEMTNHAAGWVRMDFIVPSRGLIGFRTD
FLTLTRGTGIANAVFDGYRPWAGEIRARHTGSLVSDRSGSVTPFAMIQLSDRGQFFVEPGDDTYEGQVVGINPRAEDLDV
NVTREKKLTNMRSSTADVMETLARPLELGLEQAMEFCAEDECVEVTPEVVRVRKVELDATLRARARSRAKARN
>Mature_633_residues
MDLPNDFRNVAIVAHVDHGKTTLVDAMLRQSGALSHRGDDAVERLMDSGDLEKEKGITILAKNTAVHRHHPDGTMTVINV
IDTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKALAAHLPVILVVNKTDRPDARIAEVVSESHDLLLDVA
SDLDDEAQKAAEEALGLPVLYASGRAGIASTTEPANGENPDGENLDPLFDVLLEHIPPPQGDPEAPLQALVTNLDASAFL
GRLALIRIYKGRIRKGQQVAWMREVDGHPVVTNAKITELLVTVGVERTATDEAVAGDIVAVAGIPEIMIGDTLADPDHAH
ALPRITVDEPAISVTIGTNTSPLAGKVSGHKLTARMVKSRLDSELVGNVSLKVVDIGRPDAWEVQGRGELALAVLVEQMR
REGFELTVGKPQVVTRTIDGKLHEPFEALTIDCPEEFVGAITQLMAARKGRMEEMTNHAAGWVRMDFIVPSRGLIGFRTD
FLTLTRGTGIANAVFDGYRPWAGEIRARHTGSLVSDRSGSVTPFAMIQLSDRGQFFVEPGDDTYEGQVVGINPRAEDLDV
NVTREKKLTNMRSSTADVMETLARPLELGLEQAMEFCAEDECVEVTPEVVRVRKVELDATLRARARSRAKARN

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=535, Percent_Identity=26.9158878504673, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI94966754, Length=160, Percent_Identity=38.125, Blast_Score=117, Evalue=5e-26,
Organism=Homo sapiens, GI4503483, Length=154, Percent_Identity=38.3116883116883, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI18390331, Length=143, Percent_Identity=40.5594405594406, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI217272894, Length=142, Percent_Identity=36.6197183098592, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI217272892, Length=142, Percent_Identity=36.6197183098592, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI310132016, Length=114, Percent_Identity=40.3508771929825, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI310110807, Length=114, Percent_Identity=40.3508771929825, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI310123363, Length=114, Percent_Identity=40.3508771929825, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI25306283, Length=143, Percent_Identity=38.4615384615385, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI19923640, Length=144, Percent_Identity=38.1944444444444, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI25306287, Length=144, Percent_Identity=38.1944444444444, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI34147630, Length=300, Percent_Identity=27, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI94966752, Length=112, Percent_Identity=36.6071428571429, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI53729339, Length=249, Percent_Identity=28.5140562248996, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI53729337, Length=249, Percent_Identity=28.5140562248996, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI48994988, Length=628, Percent_Identity=46.1783439490446, Blast_Score=544, Evalue=1e-156,
Organism=Escherichia coli, GI1788922, Length=310, Percent_Identity=34.8387096774194, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1789738, Length=158, Percent_Identity=36.7088607594937, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1790835, Length=390, Percent_Identity=23.3333333333333, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790412, Length=135, Percent_Identity=37.7777777777778, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789737, Length=135, Percent_Identity=37.7777777777778, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17557151, Length=257, Percent_Identity=31.1284046692607, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17552882, Length=195, Percent_Identity=30.7692307692308, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17533571, Length=140, Percent_Identity=42.8571428571429, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71988811, Length=147, Percent_Identity=38.0952380952381, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71988819, Length=147, Percent_Identity=38.0952380952381, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17556745, Length=233, Percent_Identity=31.3304721030043, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17556456, Length=363, Percent_Identity=26.9972451790634, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323320, Length=530, Percent_Identity=25.2830188679245, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6323098, Length=502, Percent_Identity=26.2948207171315, Blast_Score=130, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6324707, Length=154, Percent_Identity=39.6103896103896, Blast_Score=107, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6320593, Length=154, Percent_Identity=39.6103896103896, Blast_Score=107, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6322359, Length=145, Percent_Identity=37.2413793103448, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324166, Length=146, Percent_Identity=38.3561643835616, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324761, Length=304, Percent_Identity=27.9605263157895, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI78706572, Length=536, Percent_Identity=25, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24585711, Length=158, Percent_Identity=39.2405063291139, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24585713, Length=158, Percent_Identity=39.2405063291139, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24585709, Length=158, Percent_Identity=39.2405063291139, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24582462, Length=148, Percent_Identity=40.5405405405405, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28574573, Length=140, Percent_Identity=40, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357743, Length=140, Percent_Identity=35, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI221458488, Length=157, Percent_Identity=40.1273885350318, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19921738, Length=298, Percent_Identity=29.1946308724832, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281363316, Length=351, Percent_Identity=26.2108262108262, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17864358, Length=351, Percent_Identity=26.2108262108262, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI28572034, Length=137, Percent_Identity=33.5766423357664, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68545; Mature: 68545

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLPNDFRNVAIVAHVDHGKTTLVDAMLRQSGALSHRGDDAVERLMDSGDLEKEKGITIL
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCEEEE
AKNTAVHRHHPDGTMTVINVIDTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFV
EECCEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCHHHHH
LRKALAAHLPVILVVNKTDRPDARIAEVVSESHDLLLDVASDLDDEAQKAAEEALGLPVL
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCEEHHHHHCCCHHHHHHHHHHCCCEEE
YASGRAGIASTTEPANGENPDGENLDPLFDVLLEHIPPPQGDPEAPLQALVTNLDASAFL
EECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHH
GRLALIRIYKGRIRKGQQVAWMREVDGHPVVTNAKITELLVTVGVERTATDEAVAGDIVA
HHHHHHHHHHHHCCCCCEEEEHHHCCCCCEEECCHHHHHHHHHCCCCCCCCHHHCCCEEE
VAGIPEIMIGDTLADPDHAHALPRITVDEPAISVTIGTNTSPLAGKVSGHKLTARMVKSR
ECCCCCEEECCCCCCCCHHHCCCCEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
LDSELVGNVSLKVVDIGRPDAWEVQGRGELALAVLVEQMRREGFELTVGKPQVVTRTIDG
HCHHHHCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHCCCEEECCCCEEEEEECCC
KLHEPFEALTIDCPEEFVGAITQLMAARKGRMEEMTNHAAGWVRMDFIVPSRGLIGFRTD
CCCCCCHHEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEEECCCCCEEEEEC
FLTLTRGTGIANAVFDGYRPWAGEIRARHTGSLVSDRSGSVTPFAMIQLSDRGQFFVEPG
EEEEECCCCCHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCC
DDTYEGQVVGINPRAEDLDVNVTREKKLTNMRSSTADVMETLARPLELGLEQAMEFCAED
CCCCCCEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ECVEVTPEVVRVRKVELDATLRARARSRAKARN
CCEECCHHHHEEEEEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLPNDFRNVAIVAHVDHGKTTLVDAMLRQSGALSHRGDDAVERLMDSGDLEKEKGITIL
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCEEEE
AKNTAVHRHHPDGTMTVINVIDTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFV
EECCEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCHHHHH
LRKALAAHLPVILVVNKTDRPDARIAEVVSESHDLLLDVASDLDDEAQKAAEEALGLPVL
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCEEHHHHHCCCHHHHHHHHHHCCCEEE
YASGRAGIASTTEPANGENPDGENLDPLFDVLLEHIPPPQGDPEAPLQALVTNLDASAFL
EECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHH
GRLALIRIYKGRIRKGQQVAWMREVDGHPVVTNAKITELLVTVGVERTATDEAVAGDIVA
HHHHHHHHHHHHCCCCCEEEEHHHCCCCCEEECCHHHHHHHHHCCCCCCCCHHHCCCEEE
VAGIPEIMIGDTLADPDHAHALPRITVDEPAISVTIGTNTSPLAGKVSGHKLTARMVKSR
ECCCCCEEECCCCCCCCHHHCCCCEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
LDSELVGNVSLKVVDIGRPDAWEVQGRGELALAVLVEQMRREGFELTVGKPQVVTRTIDG
HCHHHHCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHCCCEEECCCCEEEEEECCC
KLHEPFEALTIDCPEEFVGAITQLMAARKGRMEEMTNHAAGWVRMDFIVPSRGLIGFRTD
CCCCCCHHEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEEECCCCCEEEEEC
FLTLTRGTGIANAVFDGYRPWAGEIRARHTGSLVSDRSGSVTPFAMIQLSDRGQFFVEPG
EEEEECCCCCHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCC
DDTYEGQVVGINPRAEDLDVNVTREKKLTNMRSSTADVMETLARPLELGLEQAMEFCAED
CCCCCCEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ECVEVTPEVVRVRKVELDATLRARARSRAKARN
CCEECCHHHHEEEEEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]