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The map label for this gene is fadM [H]

Identifier: 108800989

GI number: 108800989

Start: 4288669

End: 4289625

Strand: Reverse

Name: fadM [H]

Synonym: Mmcs_4025

Alternate gene names: 108800989

Gene position: 4289625-4288669 (Counterclockwise)

Preceding gene: 108800990

Following gene: 108800984

Centisome position: 75.18

GC content: 66.88

Gene sequence:

>957_bases
ATGGGTGCCTTCCAGCGCGTAGCACGTCCGGTGATCCTGGCGGCCGCCCGGTCGGACTCGCTGCGGCACACGGCGGAGCG
GCTGCCGGTGACACGGAATGTGGTGCACCGCTTCGTACCTGGCGAAAGCGTCGAAGAGGCGATGTACTGCGTTACGGGAC
TGCGGAACTCGGGCCGCATGGTCAGCGTCGACTACCTCGGCGAGGATGTGACCGACGTCGACACCGCGAACGCGACCGTC
GAGGCGTACGTGAAACTGCTCGACGCACTTGGCCGCCGGGACGAGCCGGCCGGTGCCGTCAGGCCGCTGGAGGTGTCGCT
GAAGCTCTCCGCGCTGGGTCAGGCGCTGCCGCGGGACGGCGAGAAGATCGCACTGGAGAACGCGCACACGATCTGCACGC
ACGCCCAACGCGTCGGTGCGTGGGTGACCGTCGATGCCGAGGACCACACGACCACCGACTCGACGCTGTCGATCGTGCGC
GAGTTGCGTTCGGAGTTCGACTGGTTGGGCACGGTGCTGCAGGCCTACCTGCGCCGCACGCAGGCCGACTGTGCGGAGTT
CGCCGCCTCCGGGGCGCGGATCCGGTTGTGCAAGGGGGCGTATGACGAACCGGCTTCAGTGGCGTTCCGCGATGCGGACG
AGGTCACGGACAACTATCTGCGCTGTCTGGAGACGCTGATGGCAGGACGCGGGTATCCGATGGTGGCGTCACACGATCCG
GTGGTGATCGACGCGGTGCCGGGGCTGGCGGCGGCGCAGGGACGGGCATCCGGGAGTTACGAATATCAGATGCTGTACGG
CATCCGTGACCAGGAGCAGCAACGGCTGGCCGATGCCGGAAACGTTGTTCGCGTGTATGTTCCGTTCGGCACGCAGTGGT
ATGGCTACTTCGTTCGCAGGCTCGCCGAACGGCCGGCAAACATGGCGTTCTTCCTGAGAGCCCTGGCGGGTCGCTGA

Upstream 100 bases:

>100_bases
GTCGCCGATGAACCTGCTGCGGTGGACGTCGGCGCGGTCGATCAAGGAGAACTTCGTCCCGCCGACCGACCACGACTATC
CCCACATGGAGGTGTGAGCA

Downstream 100 bases:

>100_bases
CACGTCTGTCATGATCATGATCGGCGCCGTGTCTGGCCGTGCCCGCCTTGGGTTCGGGGGAACGCGGTGGAGTCGGTCAG
GCCACGGGCGCCGTCAGGTG

Product: L-proline dehydrogenase

Products: NA

Alternate protein names: PRODH 1; Proline oxidase 1 [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MGAFQRVARPVILAAARSDSLRHTAERLPVTRNVVHRFVPGESVEEAMYCVTGLRNSGRMVSVDYLGEDVTDVDTANATV
EAYVKLLDALGRRDEPAGAVRPLEVSLKLSALGQALPRDGEKIALENAHTICTHAQRVGAWVTVDAEDHTTTDSTLSIVR
ELRSEFDWLGTVLQAYLRRTQADCAEFAASGARIRLCKGAYDEPASVAFRDADEVTDNYLRCLETLMAGRGYPMVASHDP
VVIDAVPGLAAAQGRASGSYEYQMLYGIRDQEQQRLADAGNVVRVYVPFGTQWYGYFVRRLAERPANMAFFLRALAGR

Sequences:

>Translated_318_residues
MGAFQRVARPVILAAARSDSLRHTAERLPVTRNVVHRFVPGESVEEAMYCVTGLRNSGRMVSVDYLGEDVTDVDTANATV
EAYVKLLDALGRRDEPAGAVRPLEVSLKLSALGQALPRDGEKIALENAHTICTHAQRVGAWVTVDAEDHTTTDSTLSIVR
ELRSEFDWLGTVLQAYLRRTQADCAEFAASGARIRLCKGAYDEPASVAFRDADEVTDNYLRCLETLMAGRGYPMVASHDP
VVIDAVPGLAAAQGRASGSYEYQMLYGIRDQEQQRLADAGNVVRVYVPFGTQWYGYFVRRLAERPANMAFFLRALAGR
>Mature_317_residues
GAFQRVARPVILAAARSDSLRHTAERLPVTRNVVHRFVPGESVEEAMYCVTGLRNSGRMVSVDYLGEDVTDVDTANATVE
AYVKLLDALGRRDEPAGAVRPLEVSLKLSALGQALPRDGEKIALENAHTICTHAQRVGAWVTVDAEDHTTTDSTLSIVRE
LRSEFDWLGTVLQAYLRRTQADCAEFAASGARIRLCKGAYDEPASVAFRDADEVTDNYLRCLETLMAGRGYPMVASHDPV
VIDAVPGLAAAQGRASGSYEYQMLYGIRDQEQQRLADAGNVVRVYVPFGTQWYGYFVRRLAERPANMAFFLRALAGR

Specific function: Catalyzes the oxidation of L-proline to delta-1- pyrroline-5-carboxylate (P5C) [H]

COG id: COG0506

COG function: function code E; Proline dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1787250, Length=314, Percent_Identity=29.2993630573248, Blast_Score=85, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015590
- InterPro:   IPR002872
- InterPro:   IPR008219 [H]

Pfam domain/function: PF01619 Pro_dh [H]

EC number: =1.5.99.8 [H]

Molecular weight: Translated: 34975; Mature: 34844

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAFQRVARPVILAAARSDSLRHTAERLPVTRNVVHRFVPGESVEEAMYCVTGLRNSGRM
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCE
VSVDYLGEDVTDVDTANATVEAYVKLLDALGRRDEPAGAVRPLEVSLKLSALGQALPRDG
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHCCCCC
EKIALENAHTICTHAQRVGAWVTVDAEDHTTTDSTLSIVRELRSEFDWLGTVLQAYLRRT
CEEEECCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QADCAEFAASGARIRLCKGAYDEPASVAFRDADEVTDNYLRCLETLMAGRGYPMVASHDP
HHHHHHHHCCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCEEECCCC
VVIDAVPGLAAAQGRASGSYEYQMLYGIRDQEQQRLADAGNVVRVYVPFGTQWYGYFVRR
EEEECCCCCHHHCCCCCCCEEEEEEECCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
LAERPANMAFFLRALAGR
HHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GAFQRVARPVILAAARSDSLRHTAERLPVTRNVVHRFVPGESVEEAMYCVTGLRNSGRM
CHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCE
VSVDYLGEDVTDVDTANATVEAYVKLLDALGRRDEPAGAVRPLEVSLKLSALGQALPRDG
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHCCCCC
EKIALENAHTICTHAQRVGAWVTVDAEDHTTTDSTLSIVRELRSEFDWLGTVLQAYLRRT
CEEEECCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QADCAEFAASGARIRLCKGAYDEPASVAFRDADEVTDNYLRCLETLMAGRGYPMVASHDP
HHHHHHHHCCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCEEECCCC
VVIDAVPGLAAAQGRASGSYEYQMLYGIRDQEQQRLADAGNVVRVYVPFGTQWYGYFVRR
EEEECCCCCHHHCCCCCCCEEEEEEECCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
LAERPANMAFFLRALAGR
HHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA