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The map label for this gene is guaA [H]

Identifier: 108800967

GI number: 108800967

Start: 4268263

End: 4268892

Strand: Reverse

Name: guaA [H]

Synonym: Mmcs_4003

Alternate gene names: 108800967

Gene position: 4268892-4268263 (Counterclockwise)

Preceding gene: 108800968

Following gene: 108800966

Centisome position: 74.82

GC content: 68.57

Gene sequence:

>630_bases
GTGACCGTCGCCGAGCAAAGGGTCGTCGACGACGGCCGGGTCCGGTGCGGCTGGTTGGACGGATCCCGGCTTGCCGCAGC
GGATTTCGAGCTCTACCGGGACTACCACGATTTCGAGTGGGGGCAACCGGTTCTCGAGTCCCCTGCGCTGTTCGAGCGGA
TCAGCCTGGAGGCCTTCCAGAGTGGTCTGTCGTGGCTCATCATCCTGCGCAAGCGGGAGAACTTCCGGCGGGCGTTCGAC
GGCTTCGACATCGACCGCGTCGCCGGGTACACCGACCGCGACGTCGAGCGGTTGATGGCCGACACCGGAATCGTCCGCAA
CCGCGCGAAGATCGAGGCGACCATCGCCAACGCACGCGCCGCGGCCGCCCTCTCCGACGCCGGGGTCGATCTCGCGCAGC
TGCTGTGGTCGTTCGCACCGGCCCGGCGGGGCAGGCCGGCAGGGCTGTCCGAGGTACCCGCGGTCACCCCCGAATCGACC
GCCATGGCCAAGGAACTCAAACGCCGCGGCTTCCGGTTCGTCGGTCCCACGACGGCCTACGCGCTCATGCAGGCGACCGG
AATGGTCGACGACCACATTGCGACGTGCTGGGTGCCACCGGCCGTCGAGGTGCCTCGACACAGCGGTTAA

Upstream 100 bases:

>100_bases
AGGTCGACTGGGTGCTCGACCGGCTCGGTCAGGAGATCGACGCGCTGCGCGGTGAACTGGCCGCGGTGCGCGCTGCCGCG
GAGCTGGCCGAGGAGTCCCC

Downstream 100 bases:

>100_bases
AACGGGTCTTTGCACACGTGGTCGCGCGGATAGGGAACAATAGAGGCGTTGAGTGCCGGTTCCGCCGAGAGGTGGGCGGC
CTGGCGGTTGGTTCAGTGTG

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTVAEQRVVDDGRVRCGWLDGSRLAAADFELYRDYHDFEWGQPVLESPALFERISLEAFQSGLSWLIILRKRENFRRAFD
GFDIDRVAGYTDRDVERLMADTGIVRNRAKIEATIANARAAAALSDAGVDLAQLLWSFAPARRGRPAGLSEVPAVTPEST
AMAKELKRRGFRFVGPTTAYALMQATGMVDDHIATCWVPPAVEVPRHSG

Sequences:

>Translated_209_residues
MTVAEQRVVDDGRVRCGWLDGSRLAAADFELYRDYHDFEWGQPVLESPALFERISLEAFQSGLSWLIILRKRENFRRAFD
GFDIDRVAGYTDRDVERLMADTGIVRNRAKIEATIANARAAAALSDAGVDLAQLLWSFAPARRGRPAGLSEVPAVTPEST
AMAKELKRRGFRFVGPTTAYALMQATGMVDDHIATCWVPPAVEVPRHSG
>Mature_208_residues
TVAEQRVVDDGRVRCGWLDGSRLAAADFELYRDYHDFEWGQPVLESPALFERISLEAFQSGLSWLIILRKRENFRRAFDG
FDIDRVAGYTDRDVERLMADTGIVRNRAKIEATIANARAAAALSDAGVDLAQLLWSFAPARRGRPAGLSEVPAVTPESTA
MAKELKRRGFRFVGPTTAYALMQATGMVDDHIATCWVPPAVEVPRHSG

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=189, Percent_Identity=44.973544973545, Blast_Score=173, Evalue=9e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 23212; Mature: 23080

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAEQRVVDDGRVRCGWLDGSRLAAADFELYRDYHDFEWGQPVLESPALFERISLEAFQ
CCCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHH
SGLSWLIILRKRENFRRAFDGFDIDRVAGYTDRDVERLMADTGIVRNRAKIEATIANARA
CCCEEEEEEHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
AAALSDAGVDLAQLLWSFAPARRGRPAGLSEVPAVTPESTAMAKELKRRGFRFVGPTTAY
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECHHHHH
ALMQATGMVDDHIATCWVPPAVEVPRHSG
HHHHHHCCCHHCHHEECCCCCCCCCCCCC
>Mature Secondary Structure 
TVAEQRVVDDGRVRCGWLDGSRLAAADFELYRDYHDFEWGQPVLESPALFERISLEAFQ
CCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHH
SGLSWLIILRKRENFRRAFDGFDIDRVAGYTDRDVERLMADTGIVRNRAKIEATIANARA
CCCEEEEEEHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
AAALSDAGVDLAQLLWSFAPARRGRPAGLSEVPAVTPESTAMAKELKRRGFRFVGPTTAY
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECHHHHH
ALMQATGMVDDHIATCWVPPAVEVPRHSG
HHHHHHCCCHHCHHEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]