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The map label for this gene is degP1 [H]

Identifier: 108800956

GI number: 108800956

Start: 4257746

End: 4259251

Strand: Reverse

Name: degP1 [H]

Synonym: Mmcs_3992

Alternate gene names: 108800956

Gene position: 4259251-4257746 (Counterclockwise)

Preceding gene: 108800957

Following gene: 108800955

Centisome position: 74.65

GC content: 69.32

Gene sequence:

>1506_bases
GTGATACCACCGGTGACCAATCAGGACCAGGCCAGCCGTCGCATGGCACCTCGCCCCGTCGAGCGGCCTCCGGTCGACCC
GACGGCCCAACGCGTCTTCGGCCGGCCCAGGGGGGTCAGCGGTTCGTTCCTCGGCGTGGACCAGCACCGCGGCCAGGGGG
AGTACGCCCCGAAGGACCAGGCGCCCGACCCGGTGCTCGCCGAGGCGTTCGGCCGTCCGCCGTACGCCGGTGCCGACTCC
CTGCAGCGCCATCCCGCCGACTCGGGTGCGCTCGACGCCGAACGGGCCGGTGACACCGGCGACGTCGAACCCGATCCGTG
GCGCGACCCGAACGCGCCCGTGGCGCTGGGCACCCCCGCCGTCGAGGCACCCGCACCCGTCCACGGTCCGGCACAGACCG
GCAAACTCGGTGTGCGCGACGTGCTGTTCGGTCGCAAGGTGTCCTATGTCGGGCTGGCGATCCTGCTGCTCACCGCGTTG
ATGGTCGGCGCGCTCGGCGGCTGGGTCGGCAACAAGACCGCCGAGACCGTGCAGGCGTTCACCACGTCGAAGGTCACGCT
GGAGACCAGTGACAGCGGGGACCCGCCCGAGGGACGCATCACCAAGGTGGCCGACGCGGTCGCCGACTCCGTGGTGACCA
TCGAGGCCAAGAGCGACCAGGAGGGCTCCCAGGGTTCCGGTGTGGTGATCGACGGTCGCGGCTACATCGTCACCAACAAC
CACGTGATCTCCGAGGCCGCCAACAACCCCGCCAAGTACAAGATGACCGTCGTGTTCAACGACGGTAAAGAGGTCCCCGC
CAACCTGGTCGGCCGCGACCCGAAGACCGACCTCGCCGTGCTGAAGGTCGACAACGTCGACAACCTCACCGTGGCCAAGA
TGGGTGACTCGGACAAACTGCAGGTCGGTGAGGAGGTGATCGCCGCGGGCGCCCCGCTGGGTCTGCGCAGCACCGTCACC
TCCGGCATCATCAGCGCCCTGCACCGGCCGGTTCCGCTGTCGGGCGACGGATCCGACACCGACACCGTGATCGACGGGGT
GCAGACCGACGCGTCGATCAACCACGGCAACTCCGGCGGCCCGCTGATCGACATGGACGCCAACGTGATCGGCATCAACA
CCGCGGGTAAGTCGCTGTCCGACAGCGCCAGCGGTCTGGGCTTCGCGATCCCGGTCAACGAGGTCAAGACCGTCGTCGAG
GCGTTGATCAGGGACGGCAGGATCGAGCATCCGACACTCGGCCTGACCGCGAAGTCCGTCAGCAACGACGTGGCCTCCGG
CGCCCAGGTCGCCAACGTCAAGGCGGGCAGCGCCGCCGAGCGGGCCGGCATCCTGGAGAACGACGTCGTGGTCAAGGTCG
GCAACCGCGACGTCGCGGACGCCGACGAGTTCGTGGTCGCGGTGCGTCAGCTCAAGATCAATGAACCCGCCCCGATCGAG
GTCGTCCGCGACGGCCGTCCGGTGACGCTCACCGTGACACCGACGCCAGACGCCGCCACCGACTGA

Upstream 100 bases:

>100_bases
TTGCTGACGACCAAACGCGGGACCGGCGCAGACGCCGGTAGGCTGGGTTCTGGAGTCGAGCAGCGACTGCGCCCGGTCAT
GCCGGGTGCTCCGATAGAGA

Downstream 100 bases:

>100_bases
TGTTCGCCAACATCGGCTGGGGGGAGATGCTGATCCTGGTGATCGCCGGGCTGGTGATCCTGGGACCGGAACGGCTGCCC
GGGGCGATCCGCTGGACCTC

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MIPPVTNQDQASRRMAPRPVERPPVDPTAQRVFGRPRGVSGSFLGVDQHRGQGEYAPKDQAPDPVLAEAFGRPPYAGADS
LQRHPADSGALDAERAGDTGDVEPDPWRDPNAPVALGTPAVEAPAPVHGPAQTGKLGVRDVLFGRKVSYVGLAILLLTAL
MVGALGGWVGNKTAETVQAFTTSKVTLETSDSGDPPEGRITKVADAVADSVVTIEAKSDQEGSQGSGVVIDGRGYIVTNN
HVISEAANNPAKYKMTVVFNDGKEVPANLVGRDPKTDLAVLKVDNVDNLTVAKMGDSDKLQVGEEVIAAGAPLGLRSTVT
SGIISALHRPVPLSGDGSDTDTVIDGVQTDASINHGNSGGPLIDMDANVIGINTAGKSLSDSASGLGFAIPVNEVKTVVE
ALIRDGRIEHPTLGLTAKSVSNDVASGAQVANVKAGSAAERAGILENDVVVKVGNRDVADADEFVVAVRQLKINEPAPIE
VVRDGRPVTLTVTPTPDAATD

Sequences:

>Translated_501_residues
MIPPVTNQDQASRRMAPRPVERPPVDPTAQRVFGRPRGVSGSFLGVDQHRGQGEYAPKDQAPDPVLAEAFGRPPYAGADS
LQRHPADSGALDAERAGDTGDVEPDPWRDPNAPVALGTPAVEAPAPVHGPAQTGKLGVRDVLFGRKVSYVGLAILLLTAL
MVGALGGWVGNKTAETVQAFTTSKVTLETSDSGDPPEGRITKVADAVADSVVTIEAKSDQEGSQGSGVVIDGRGYIVTNN
HVISEAANNPAKYKMTVVFNDGKEVPANLVGRDPKTDLAVLKVDNVDNLTVAKMGDSDKLQVGEEVIAAGAPLGLRSTVT
SGIISALHRPVPLSGDGSDTDTVIDGVQTDASINHGNSGGPLIDMDANVIGINTAGKSLSDSASGLGFAIPVNEVKTVVE
ALIRDGRIEHPTLGLTAKSVSNDVASGAQVANVKAGSAAERAGILENDVVVKVGNRDVADADEFVVAVRQLKINEPAPIE
VVRDGRPVTLTVTPTPDAATD
>Mature_501_residues
MIPPVTNQDQASRRMAPRPVERPPVDPTAQRVFGRPRGVSGSFLGVDQHRGQGEYAPKDQAPDPVLAEAFGRPPYAGADS
LQRHPADSGALDAERAGDTGDVEPDPWRDPNAPVALGTPAVEAPAPVHGPAQTGKLGVRDVLFGRKVSYVGLAILLLTAL
MVGALGGWVGNKTAETVQAFTTSKVTLETSDSGDPPEGRITKVADAVADSVVTIEAKSDQEGSQGSGVVIDGRGYIVTNN
HVISEAANNPAKYKMTVVFNDGKEVPANLVGRDPKTDLAVLKVDNVDNLTVAKMGDSDKLQVGEEVIAAGAPLGLRSTVT
SGIISALHRPVPLSGDGSDTDTVIDGVQTDASINHGNSGGPLIDMDANVIGINTAGKSLSDSASGLGFAIPVNEVKTVVE
ALIRDGRIEHPTLGLTAKSVSNDVASGAQVANVKAGSAAERAGILENDVVVKVGNRDVADADEFVVAVRQLKINEPAPIE
VVRDGRPVTLTVTPTPDAATD

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=323, Percent_Identity=31.5789473684211, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI4506141, Length=324, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI24308541, Length=321, Percent_Identity=31.1526479750779, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI7019477, Length=299, Percent_Identity=32.1070234113712, Blast_Score=116, Evalue=5e-26,
Organism=Escherichia coli, GI1789629, Length=278, Percent_Identity=37.0503597122302, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1786356, Length=277, Percent_Identity=36.8231046931408, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1789630, Length=288, Percent_Identity=36.1111111111111, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646839, Length=329, Percent_Identity=30.3951367781155, Blast_Score=130, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 51763; Mature: 51763

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPPVTNQDQASRRMAPRPVERPPVDPTAQRVFGRPRGVSGSFLGVDQHRGQGEYAPKDQ
CCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCC
APDPVLAEAFGRPPYAGADSLQRHPADSGALDAERAGDTGDVEPDPWRDPNAPVALGTPA
CCCCHHHHHCCCCCCCCCHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEECCCC
VEAPAPVHGPAQTGKLGVRDVLFGRKVSYVGLAILLLTALMVGALGGWVGNKTAETVQAF
CCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TTSKVTLETSDSGDPPEGRITKVADAVADSVVTIEAKSDQEGSQGSGVVIDGRGYIVTNN
HCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCEEEEECC
HVISEAANNPAKYKMTVVFNDGKEVPANLVGRDPKTDLAVLKVDNVDNLTVAKMGDSDKL
EEEECCCCCCCEEEEEEEECCCCCCCHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCH
QVGEEVIAAGAPLGLRSTVTSGIISALHRPVPLSGDGSDTDTVIDGVQTDASINHGNSGG
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCC
PLIDMDANVIGINTAGKSLSDSASGLGFAIPVNEVKTVVEALIRDGRIEHPTLGLTAKSV
CEEEECCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEHHHH
SNDVASGAQVANVKAGSAAERAGILENDVVVKVGNRDVADADEFVVAVRQLKINEPAPIE
HHHHHCCCEEEEECCCCHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEE
VVRDGRPVTLTVTPTPDAATD
EEECCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MIPPVTNQDQASRRMAPRPVERPPVDPTAQRVFGRPRGVSGSFLGVDQHRGQGEYAPKDQ
CCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCC
APDPVLAEAFGRPPYAGADSLQRHPADSGALDAERAGDTGDVEPDPWRDPNAPVALGTPA
CCCCHHHHHCCCCCCCCCHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEECCCC
VEAPAPVHGPAQTGKLGVRDVLFGRKVSYVGLAILLLTALMVGALGGWVGNKTAETVQAF
CCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TTSKVTLETSDSGDPPEGRITKVADAVADSVVTIEAKSDQEGSQGSGVVIDGRGYIVTNN
HCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCEEEEECC
HVISEAANNPAKYKMTVVFNDGKEVPANLVGRDPKTDLAVLKVDNVDNLTVAKMGDSDKL
EEEECCCCCCCEEEEEEEECCCCCCCHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCH
QVGEEVIAAGAPLGLRSTVTSGIISALHRPVPLSGDGSDTDTVIDGVQTDASINHGNSGG
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCC
PLIDMDANVIGINTAGKSLSDSASGLGFAIPVNEVKTVVEALIRDGRIEHPTLGLTAKSV
CEEEECCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEHHHH
SNDVASGAQVANVKAGSAAERAGILENDVVVKVGNRDVADADEFVVAVRQLKINEPAPIE
HHHHHCCCEEEEECCCCHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEE
VVRDGRPVTLTVTPTPDAATD
EEECCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550509; 11481430 [H]