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The map label for this gene is rho [H]

Identifier: 108800857

GI number: 108800857

Start: 4144146

End: 4146137

Strand: Reverse

Name: rho [H]

Synonym: Mmcs_3893

Alternate gene names: 108800857

Gene position: 4146137-4144146 (Counterclockwise)

Preceding gene: 108800858

Following gene: 108800855

Centisome position: 72.67

GC content: 69.03

Gene sequence:

>1992_bases
GTGACCGATACGGACCTCTTCACGGCCGACAGCGCTGAGCGAACAGAGTTGCCGAACGTCGTGAACACCGAAACTTCCAC
GGCGTCGGAGGGCCCGGCCGTCACCACGACGACCGCGGAGTCCGCCCCGACCGCCGACGTGGCGTCGGGTGACCGTGCCG
CCTCGCTGACCTCGATGGTCCTGCCGGAACTGCGCGCGCTGGCGCGCCAGATCGGCGTCGAAGGCGCCTCCGGCATGCGC
AAGAGCGAACTGATCGCCGCGATCCGCGAACGCCGCGGCGACGGCGGTGCCGCCAAGGCGGAGAGCGCCGCTGCACCGCA
GACGCCCCCGCGCCGTGAGCGTCGCAGCGCATCGCGTCAGGCCGGCGCCGCCGAGGCCAAGGCTCCAGAGGCCCTCGAGG
CCAAGGCCCCCGAGGTGAAGGCCCCCGAGGTGAAGGCCCCCGAGGTGAAGGCTGATGCACCGGCCGAAGAGGCCGCTGCG
GAGCCCAAGACCGAGCGGCCCAGGAACGACCGCACCAAGGCCGAGAAGCCCGCGGCGCAGCAGCCCGACGGCGAGCAGCC
CAAGGGAGACCAGCCGAAGGGCGAGCAGTCCAGGGGCGATCAGCGCCGGTCCGATCGTCCGCGGGGCGATCAGTCCGACA
CCAGGTCCGACGACCGGTCCGACAGTGACCAGCAGCAGGGCCAGGGCAACCGAAACAACAGCAACAACAGCGCCGATGGC
GACGACGACGGCGACGGCCGGGGTGGCCGCCGCGGCCGCCGGTTCCGCGACCGCCGGCGCCGTGGTGAGCGCGGTGGCGA
GGGCGGCGGCGGTGGCGATACCGAGATCCGCGAGGACGACGTCGTCCAGCCCGTCGCCGGCATCCTCGACGTCCTCGACA
ACTACGCGTTCGTCCGCACCTCGGGCTACCTGCCCGGTCCGAACGACGTCTACGTGTCGATGAACATGGTGCGCAAGAAC
GGGCTGCGCCGCGGCGACGCCGTCACCGGTGCGGTCAAGGTGCCCAAGGAGGGCGAAGGCGGCGGTCAGAACCAGCGCCA
GAAGTTCAATCCGCTGGTGCGTCTCGACAGCGTCAACGGCGGGCCGGTCGAGGATGCGAGGAAGCGTCCCGAATTCGGCA
AGCTGACCCCGCTGTACCCCAATCAGCGGCTGCGTCTGGAGACCTCTCCGGACAAGCTGACCACCCGCGTCATCGACCTG
ATCATGCCGATCGGCAAGGGGCAGCGCGCGCTGATCGTGTCGCCGCCCAAGGCCGGTAAGACCACGATCATGCAGGACAT
CGCCAACGCGATCACCCGCAACAACCCGGAATGCCACCTGATGGTGGTGCTCGTCGACGAGCGTCCGGAAGAGGTCACCG
ACATGCAGCGCTCGGTCAAGGGTGAGGTCATCGCCTCGACCTTCGACCGGCCGCCGTCCGACCACACCACGGTCGCCGAA
CTGGCCATCGAGCGCGCCAAGCGCCTGGTGGAGCAGGGCAAGGACGTCGTGGTGCTCCTCGACTCGATCACCCGCCTCGG
CCGGGCCTACAACAACGCCTCGCCGGCCTCGGGCCGCATCCTGTCCGGTGGTGTGGACTCGACCGCGTTGTACCCGCCGA
AGCGCTTCCTGGGTGCCGCACGCAACATCGAAGAGGGCGGCTCACTGACCATCGTCGCGACCGCGATGGTGGAGACCGGT
TCGACCGGTGACACGGTCATCTTCGAGGAGTTCAAGGGCACCGGTAACGCCGAGCTCAAGCTCGATCGCAAGATCGCCGA
ACGCCGGGTGTTCCCCGCGGTCGACGTGAACCCGTCGGGCACCCGTAAGGACGAGCTGCTGCTCGGCCCCGACGAGTTCG
CGATCGTGCACAAGCTGCGCCGGGTGCTGTCGGGTCTCGACAGCCATCAGGCCATCGACCTGCTGATGAGTCAGCTGCGC
AAGACCAAGACGAACTACGAGTTCCTGGTGCAGGTCTCCAAGAACACACCGGGGTCGGTGGACAACGACTGA

Upstream 100 bases:

>100_bases
CGGCGACGGTGGAACCTTCGCGTTCGGCGGATCGGCTGAACGCCGAGGACATTTTGAGCCCTCGCGCTAACGCAATCAGC
GAGGGAAAGAAAGGAAATCC

Downstream 100 bases:

>100_bases
TCCGTGCTACGAGGAGGGCCCCCGCCGTCGAGGTGGGGGCCTTTTTCGCGTCAGACCGCGGGATCGGCCGTCAACCCCGG
CATCACATACCTGCGGATGT

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 663; Mature: 662

Protein sequence:

>663_residues
MTDTDLFTADSAERTELPNVVNTETSTASEGPAVTTTTAESAPTADVASGDRAASLTSMVLPELRALARQIGVEGASGMR
KSELIAAIRERRGDGGAAKAESAAAPQTPPRRERRSASRQAGAAEAKAPEALEAKAPEVKAPEVKAPEVKADAPAEEAAA
EPKTERPRNDRTKAEKPAAQQPDGEQPKGDQPKGEQSRGDQRRSDRPRGDQSDTRSDDRSDSDQQQGQGNRNNSNNSADG
DDDGDGRGGRRGRRFRDRRRRGERGGEGGGGGDTEIREDDVVQPVAGILDVLDNYAFVRTSGYLPGPNDVYVSMNMVRKN
GLRRGDAVTGAVKVPKEGEGGGQNQRQKFNPLVRLDSVNGGPVEDARKRPEFGKLTPLYPNQRLRLETSPDKLTTRVIDL
IMPIGKGQRALIVSPPKAGKTTIMQDIANAITRNNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTTVAE
LAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIEEGGSLTIVATAMVETG
STGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKDELLLGPDEFAIVHKLRRVLSGLDSHQAIDLLMSQLR
KTKTNYEFLVQVSKNTPGSVDND

Sequences:

>Translated_663_residues
MTDTDLFTADSAERTELPNVVNTETSTASEGPAVTTTTAESAPTADVASGDRAASLTSMVLPELRALARQIGVEGASGMR
KSELIAAIRERRGDGGAAKAESAAAPQTPPRRERRSASRQAGAAEAKAPEALEAKAPEVKAPEVKAPEVKADAPAEEAAA
EPKTERPRNDRTKAEKPAAQQPDGEQPKGDQPKGEQSRGDQRRSDRPRGDQSDTRSDDRSDSDQQQGQGNRNNSNNSADG
DDDGDGRGGRRGRRFRDRRRRGERGGEGGGGGDTEIREDDVVQPVAGILDVLDNYAFVRTSGYLPGPNDVYVSMNMVRKN
GLRRGDAVTGAVKVPKEGEGGGQNQRQKFNPLVRLDSVNGGPVEDARKRPEFGKLTPLYPNQRLRLETSPDKLTTRVIDL
IMPIGKGQRALIVSPPKAGKTTIMQDIANAITRNNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTTVAE
LAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIEEGGSLTIVATAMVETG
STGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKDELLLGPDEFAIVHKLRRVLSGLDSHQAIDLLMSQLR
KTKTNYEFLVQVSKNTPGSVDND
>Mature_662_residues
TDTDLFTADSAERTELPNVVNTETSTASEGPAVTTTTAESAPTADVASGDRAASLTSMVLPELRALARQIGVEGASGMRK
SELIAAIRERRGDGGAAKAESAAAPQTPPRRERRSASRQAGAAEAKAPEALEAKAPEVKAPEVKAPEVKADAPAEEAAAE
PKTERPRNDRTKAEKPAAQQPDGEQPKGDQPKGEQSRGDQRRSDRPRGDQSDTRSDDRSDSDQQQGQGNRNNSNNSADGD
DDGDGRGGRRGRRFRDRRRRGERGGEGGGGGDTEIREDDVVQPVAGILDVLDNYAFVRTSGYLPGPNDVYVSMNMVRKNG
LRRGDAVTGAVKVPKEGEGGGQNQRQKFNPLVRLDSVNGGPVEDARKRPEFGKLTPLYPNQRLRLETSPDKLTTRVIDLI
MPIGKGQRALIVSPPKAGKTTIMQDIANAITRNNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTTVAEL
AIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIEEGGSLTIVATAMVETGS
TGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKDELLLGPDEFAIVHKLRRVLSGLDSHQAIDLLMSQLRK
TKTNYEFLVQVSKNTPGSVDND

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=369, Percent_Identity=55.5555555555556, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 71418; Mature: 71287

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTDLFTADSAERTELPNVVNTETSTASEGPAVTTTTAESAPTADVASGDRAASLTSMV
CCCCCCEECCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHCCCCHHHHHHHHH
LPELRALARQIGVEGASGMRKSELIAAIRERRGDGGAAKAESAAAPQTPPRRERRSASRQ
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AGAAEAKAPEALEAKAPEVKAPEVKAPEVKADAPAEEAAAEPKTERPRNDRTKAEKPAAQ
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHCCCCCCC
QPDGEQPKGDQPKGEQSRGDQRRSDRPRGDQSDTRSDDRSDSDQQQGQGNRNNSNNSADG
CCCCCCCCCCCCCCCHHCCHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCC
DDDGDGRGGRRGRRFRDRRRRGERGGEGGGGGDTEIREDDVVQPVAGILDVLDNYAFVRT
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEE
SGYLPGPNDVYVSMNMVRKNGLRRGDAVTGAVKVPKEGEGGGQNQRQKFNPLVRLDSVNG
CCCCCCCCCEEEEEHHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCEEEEECCCC
GPVEDARKRPEFGKLTPLYPNQRLRLETSPDKLTTRVIDLIMPIGKGQRALIVSPPKAGK
CCCHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
TTIMQDIANAITRNNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTTVAE
HHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHH
LAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAA
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHH
RNIEEGGSLTIVATAMVETGSTGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSG
CCCCCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCEEEEHHHHHHHHCCCCCCCCCCC
TRKDELLLGPDEFAIVHKLRRVLSGLDSHQAIDLLMSQLRKTKTNYEFLVQVSKNTPGSV
CCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
DND
CCC
>Mature Secondary Structure 
TDTDLFTADSAERTELPNVVNTETSTASEGPAVTTTTAESAPTADVASGDRAASLTSMV
CCCCCEECCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHCCCCHHHHHHHHH
LPELRALARQIGVEGASGMRKSELIAAIRERRGDGGAAKAESAAAPQTPPRRERRSASRQ
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AGAAEAKAPEALEAKAPEVKAPEVKAPEVKADAPAEEAAAEPKTERPRNDRTKAEKPAAQ
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHCCCCCCC
QPDGEQPKGDQPKGEQSRGDQRRSDRPRGDQSDTRSDDRSDSDQQQGQGNRNNSNNSADG
CCCCCCCCCCCCCCCHHCCHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCC
DDDGDGRGGRRGRRFRDRRRRGERGGEGGGGGDTEIREDDVVQPVAGILDVLDNYAFVRT
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEE
SGYLPGPNDVYVSMNMVRKNGLRRGDAVTGAVKVPKEGEGGGQNQRQKFNPLVRLDSVNG
CCCCCCCCCEEEEEHHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCEEEEECCCC
GPVEDARKRPEFGKLTPLYPNQRLRLETSPDKLTTRVIDLIMPIGKGQRALIVSPPKAGK
CCCHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
TTIMQDIANAITRNNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTTVAE
HHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHH
LAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAA
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHH
RNIEEGGSLTIVATAMVETGSTGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSG
CCCCCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCEEEEHHHHHHHHCCCCCCCCCCC
TRKDELLLGPDEFAIVHKLRRVLSGLDSHQAIDLLMSQLRKTKTNYEFLVQVSKNTPGSV
CCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
DND
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]