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The map label for this gene is mec [H]

Identifier: 108800814

GI number: 108800814

Start: 4094364

End: 4094777

Strand: Reverse

Name: mec [H]

Synonym: Mmcs_3850

Alternate gene names: 108800814

Gene position: 4094777-4094364 (Counterclockwise)

Preceding gene: 108800815

Following gene: 108800813

Centisome position: 71.77

GC content: 67.87

Gene sequence:

>414_bases
GTGCTGGTGATCCGTGCCGATCTGGTCGACGCCATGGTCGCGCACGCCCGCGCCGACCATCCCGACGAGGCGTGCGGCGT
CATCGCCGGCCCGGAGGGGTCCGACCGGCCCGAACGGCACGTCGCGATGCTCAACGCGGAGCGTTCGCCGACGTTCTACC
GGTTCGACTCGATGGAGCAGCTCAAGGTGTGGCGCTCGATGGACGAGGCCGACGAGGTGCCGGTGGTGATCTACCACTCG
CACACCGGCACCGAGGCCTACCCGAGCCGTACCGACATCGCGCTGGCGTCCGAACCCGATGCCCACTACGTCCTGGTGTC
CACCCGCGACCCGGACGAACACGAACTACGCAGCTACCGCATCGTCGACGGCGTGGTGAGCGAAGAGCCCGTCAAGATCG
TCGACACCTACTGA

Upstream 100 bases:

>100_bases
GGGGTGCTGGCCGCCGAGGGTGCGGCCGGAATACCGACGTACCGGGACCTGTTGCCCGGAGCGTTCGGGTGAGAAGTCCG
TGCAGCGATAGGGGAGTGCA

Downstream 100 bases:

>100_bases
AATCACGCTTACCGAGAATCGAAGGAGTCCGTCACATGACCGTTTCGGTGTCCATCCCGACCATCCTGCGCACCCACACC
GGCGGGGAGAAGCGCGTCAG

Product: Mov34/MPN/PAD-1

Products: NA

Alternate protein names: Metallocarboxypeptidase Mec [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MLVIRADLVDAMVAHARADHPDEACGVIAGPEGSDRPERHVAMLNAERSPTFYRFDSMEQLKVWRSMDEADEVPVVIYHS
HTGTEAYPSRTDIALASEPDAHYVLVSTRDPDEHELRSYRIVDGVVSEEPVKIVDTY

Sequences:

>Translated_137_residues
MLVIRADLVDAMVAHARADHPDEACGVIAGPEGSDRPERHVAMLNAERSPTFYRFDSMEQLKVWRSMDEADEVPVVIYHS
HTGTEAYPSRTDIALASEPDAHYVLVSTRDPDEHELRSYRIVDGVVSEEPVKIVDTY
>Mature_137_residues
MLVIRADLVDAMVAHARADHPDEACGVIAGPEGSDRPERHVAMLNAERSPTFYRFDSMEQLKVWRSMDEADEVPVVIYHS
HTGTEAYPSRTDIALASEPDAHYVLVSTRDPDEHELRSYRIVDGVVSEEPVKIVDTY

Specific function: Protease that hydrolyzes the covalent CysO-cysteine adduct synthesized by CysM to release L-cysteine and regenerate CysO [H]

COG id: COG1310

COG function: function code R; Predicted metal-dependent protease of the PAD1/JAB1 superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MPN (JAB/Mov34) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000555 [H]

Pfam domain/function: PF01398 Mov34 [H]

EC number: NA

Molecular weight: Translated: 15392; Mature: 15392

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVIRADLVDAMVAHARADHPDEACGVIAGPEGSDRPERHVAMLNAERSPTFYRFDSMEQ
CEEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCEEECCCHHH
LKVWRSMDEADEVPVVIYHSHTGTEAYPSRTDIALASEPDAHYVLVSTRDPDEHELRSYR
HHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCEEEEECCCCCHHHHHEEE
IVDGVVSEEPVKIVDTY
EECCCCCCCCEEEEECC
>Mature Secondary Structure
MLVIRADLVDAMVAHARADHPDEACGVIAGPEGSDRPERHVAMLNAERSPTFYRFDSMEQ
CEEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCEEECCCHHH
LKVWRSMDEADEVPVVIYHSHTGTEAYPSRTDIALASEPDAHYVLVSTRDPDEHELRSYR
HHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCEEEEECCCCCHHHHHEEE
IVDGVVSEEPVKIVDTY
EECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]