| Definition | Mycobacterium sp. MCS chromosome, complete genome. |
|---|---|
| Accession | NC_008146 |
| Length | 5,705,448 |
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The map label for this gene is fabG [H]
Identifier: 108800726
GI number: 108800726
Start: 4014351
End: 4015157
Strand: Reverse
Name: fabG [H]
Synonym: Mmcs_3761
Alternate gene names: 108800726
Gene position: 4015157-4014351 (Counterclockwise)
Preceding gene: 108800727
Following gene: 108800724
Centisome position: 70.37
GC content: 72.0
Gene sequence:
>807_bases ATGGCCATCGACCCGTCCGGCATCCTGCTCACCGACCGCGTCGCCGTGGTCACCGGCGGCGGCGCCGGTATCGGCCTCGG TATCGCCGCGGGTCTGGCGGCGTTCGGCGCCCGGGTGGCGATCTGGGAGCGTGACGCCGACCGCTGTGCGGTCGCCGCGG AATCCGTCGGCGGGCTCGGTATCGTCACCGATGTCCGCGACAGCGCCGCGGTGACGGCGGCCCTCGACCGCACGGTCGCC GAACTGGGCACGGTGACGATCCTGGTCAACAACGCGGGCGGTACGTTCTCCTCACCGCTGCTGGAGACCAGCGAAAACGC CTGGGACGCACTGTACAAGGCGAATCTGCGACATGTGCTGCTGTGCACGCAGCGGGTCGCGCAGCAGATGGTGGCCGCCG GGGTGGGCGGCAGCGTCATCACGGTGACGTCGATCGAAGGGGTCCGCGCCGCCCCGGGTTACGCGGCCTACGCGGCGGCC AAGGCCGGCGTCGTCAACTACACGCAGACGGCCGCCTTCGAACTGGCCCCGCACGGTATCCGGGTCAACGCGCTGGCGCC CGACGTCGTCGTCACCGAAGGGTTGGTGGCGCTCTCGCCCGGTGGGCTGCCCGCCGGAATCGGCGACGCGATACCGATGG GCCGGCCCGGGACCGTGGACGAGATCGCCGGGGCCGCAGTGTTCCTCGCGTCCGATCTGGCCGGATACATCACCGGTGAG ACGCTGCACGTCGACGGCGGAACCCACGCGGCGGGCGGCTGGTACCGGCATCCGCGGACCGGTGCGGCCACCCTGGGCCC CGGTTAA
Upstream 100 bases:
>100_bases GAAGAGCTTCTCGCCGAACTGGGCCTCACCGCGGACGACATCGCCCGACTCGCCGCCGACAAGGTGATCGGCCACACCGT CTGACTGGTTGACTGGCGCC
Downstream 100 bases:
>100_bases CGGGGCCGGTCGAGTCCCGGGTCGCCGAGCCGGGAGCGGATCGCCGCCCACGGGTCGGCGTACTTGCCGGGCTTGTTCCG GTAGGCGCCCTGGCGGGCGA
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 268; Mature: 267
Protein sequence:
>268_residues MAIDPSGILLTDRVAVVTGGGAGIGLGIAAGLAAFGARVAIWERDADRCAVAAESVGGLGIVTDVRDSAAVTAALDRTVA ELGTVTILVNNAGGTFSSPLLETSENAWDALYKANLRHVLLCTQRVAQQMVAAGVGGSVITVTSIEGVRAAPGYAAYAAA KAGVVNYTQTAAFELAPHGIRVNALAPDVVVTEGLVALSPGGLPAGIGDAIPMGRPGTVDEIAGAAVFLASDLAGYITGE TLHVDGGTHAAGGWYRHPRTGAATLGPG
Sequences:
>Translated_268_residues MAIDPSGILLTDRVAVVTGGGAGIGLGIAAGLAAFGARVAIWERDADRCAVAAESVGGLGIVTDVRDSAAVTAALDRTVA ELGTVTILVNNAGGTFSSPLLETSENAWDALYKANLRHVLLCTQRVAQQMVAAGVGGSVITVTSIEGVRAAPGYAAYAAA KAGVVNYTQTAAFELAPHGIRVNALAPDVVVTEGLVALSPGGLPAGIGDAIPMGRPGTVDEIAGAAVFLASDLAGYITGE TLHVDGGTHAAGGWYRHPRTGAATLGPG >Mature_267_residues AIDPSGILLTDRVAVVTGGGAGIGLGIAAGLAAFGARVAIWERDADRCAVAAESVGGLGIVTDVRDSAAVTAALDRTVAE LGTVTILVNNAGGTFSSPLLETSENAWDALYKANLRHVLLCTQRVAQQMVAAGVGGSVITVTSIEGVRAAPGYAAYAAAK AGVVNYTQTAAFELAPHGIRVNALAPDVVVTEGLVALSPGGLPAGIGDAIPMGRPGTVDEIAGAAVFLASDLAGYITGET LHVDGGTHAAGGWYRHPRTGAATLGPG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=242, Percent_Identity=36.3636363636364, Blast_Score=133, Evalue=2e-31, Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=37.7952755905512, Blast_Score=129, Evalue=4e-30, Organism=Homo sapiens, GI10190704, Length=260, Percent_Identity=35.3846153846154, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=32.8063241106719, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=34.5528455284553, Blast_Score=111, Evalue=8e-25, Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=35.1464435146443, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI4503301, Length=226, Percent_Identity=31.4159292035398, Blast_Score=105, Evalue=6e-23, Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=32.0158102766798, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=32.6771653543307, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=34.4086021505376, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI33667109, Length=200, Percent_Identity=34, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI66933014, Length=194, Percent_Identity=29.3814432989691, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI59889578, Length=222, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI31542939, Length=193, Percent_Identity=32.1243523316062, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI142976729, Length=191, Percent_Identity=27.2251308900524, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI302344755, Length=108, Percent_Identity=37.037037037037, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4504505, Length=207, Percent_Identity=28.9855072463768, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI209862901, Length=196, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI19923983, Length=196, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=8e-12, Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=40.1673640167364, Blast_Score=147, Evalue=6e-37, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=37.8048780487805, Blast_Score=135, Evalue=3e-33, Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=32.4, Blast_Score=121, Evalue=5e-29, Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=33.1932773109244, Blast_Score=117, Evalue=9e-28, Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=35.8565737051793, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=30.7086614173228, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=30.8, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=28.515625, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=31.1475409836066, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1786812, Length=241, Percent_Identity=30.2904564315353, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI2367365, Length=239, Percent_Identity=28.0334728033473, Blast_Score=73, Evalue=2e-14, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=42.3387096774194, Blast_Score=147, Evalue=4e-36, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=40.080971659919, Blast_Score=147, Evalue=8e-36, Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=32.5925925925926, Blast_Score=120, Evalue=7e-28, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=31.6981132075472, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=33.201581027668, Blast_Score=117, Evalue=9e-27, Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=32.5842696629214, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=33.7349397590361, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17562910, Length=275, Percent_Identity=29.4545454545455, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI71994600, Length=262, Percent_Identity=30.1526717557252, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI17561272, Length=251, Percent_Identity=36.6533864541833, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=32.1138211382114, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=31.4741035856574, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17559104, Length=272, Percent_Identity=31.6176470588235, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=32.824427480916, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI71994604, Length=262, Percent_Identity=30.5343511450382, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=29.6296296296296, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562904, Length=273, Percent_Identity=30.03663003663, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=30.2583025830258, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=30.3703703703704, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=30.0751879699248, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=30.3846153846154, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17538486, Length=277, Percent_Identity=31.0469314079422, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=28.6290322580645, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=26.6409266409266, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=29.277566539924, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=27.7777777777778, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17538182, Length=247, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17544670, Length=279, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71982365, Length=209, Percent_Identity=29.6650717703349, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17568967, Length=255, Percent_Identity=27.0588235294118, Blast_Score=70, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=29.3436293436293, Blast_Score=96, Evalue=8e-21, Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=26.1538461538462, Blast_Score=67, Evalue=4e-12, Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=35.7976653696498, Blast_Score=139, Evalue=3e-33, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=35.7142857142857, Blast_Score=132, Evalue=2e-31, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=35.4838709677419, Blast_Score=130, Evalue=8e-31, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=33.6, Blast_Score=126, Evalue=2e-29, Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=35.3174603174603, Blast_Score=120, Evalue=1e-27, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=34.0080971659919, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=31.6872427983539, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24644337, Length=257, Percent_Identity=29.5719844357977, Blast_Score=88, Evalue=7e-18, Organism=Drosophila melanogaster, GI116007236, Length=206, Percent_Identity=32.5242718446602, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24641232, Length=215, Percent_Identity=29.7674418604651, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI116007234, Length=233, Percent_Identity=33.4763948497854, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI18859837, Length=200, Percent_Identity=31.5, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI116007232, Length=183, Percent_Identity=34.9726775956284, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007238, Length=182, Percent_Identity=31.3186813186813, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=30.6878306878307, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=30.6878306878307, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24584752, Length=186, Percent_Identity=27.4193548387097, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26604; Mature: 26473
Theoretical pI: Translated: 4.81; Mature: 4.81
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 0.7 %Met (Mature Protein) 1.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAIDPSGILLTDRVAVVTGGGAGIGLGIAAGLAAFGARVAIWERDADRCAVAAESVGGLG CCCCCCCEEEECCEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCEE IVTDVRDSAAVTAALDRTVAELGTVTILVNNAGGTFSSPLLETSENAWDALYKANLRHVL EEEECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHCCCHHHHHHHHHCCHHHH LCTQRVAQQMVAAGVGGSVITVTSIEGVRAAPGYAAYAAAKAGVVNYTQTAAFELAPHGI HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCEECCHHEEEEECCCCE RVNALAPDVVVTEGLVALSPGGLPAGIGDAIPMGRPGTVDEIAGAAVFLASDLAGYITGE EEEEECCCEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC TLHVDGGTHAAGGWYRHPRTGAATLGPG EEEECCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure AIDPSGILLTDRVAVVTGGGAGIGLGIAAGLAAFGARVAIWERDADRCAVAAESVGGLG CCCCCCEEEECCEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCEE IVTDVRDSAAVTAALDRTVAELGTVTILVNNAGGTFSSPLLETSENAWDALYKANLRHVL EEEECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHCCCHHHHHHHHHCCHHHH LCTQRVAQQMVAAGVGGSVITVTSIEGVRAAPGYAAYAAAKAGVVNYTQTAAFELAPHGI HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCEECCHHEEEEECCCCE RVNALAPDVVVTEGLVALSPGGLPAGIGDAIPMGRPGTVDEIAGAAVFLASDLAGYITGE EEEEECCCEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC TLHVDGGTHAAGGWYRHPRTGAATLGPG EEEECCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10684935 [H]