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The map label for this gene is frc [H]

Identifier: 108800640

GI number: 108800640

Start: 3932663

End: 3933871

Strand: Reverse

Name: frc [H]

Synonym: Mmcs_3675

Alternate gene names: 108800640

Gene position: 3933871-3932663 (Counterclockwise)

Preceding gene: 108800641

Following gene: 108800639

Centisome position: 68.95

GC content: 68.82

Gene sequence:

>1209_bases
ATGAGCAGGCCATTGGAGGGCATCCGCGTCCTCGAGGTCGCGATGTACGGGTTCGTCCCGTCGTGCGGTGCGGTGCTCGG
TGAGTGGGGCGCCGAGGTCATCAAGGTCGAACACGCGGTGACCGGCGATCCTCAGCGCGGACTGCGTCAGACCGGACCGC
TGCGGGTGGAGGGCGATCCGAACCCGAACATCGAACACGCCAACCGGGGCAAGCGCAGCATCGGGCTGGACATGTCGGTG
CCCGAGGGCCGGGAGGTCCTGCTCGAACTCGCCCGGCGCGCGGACGTGTTCCTGACCAGCTTCCTGCCCGGACATCGGCA
GAAGTTCGGCATCGACGTCGACGACATCCGTGCGGTGAACCCGAACATCGTCTACGCCCGCGGCAGCGCGCTCGGACCGC
GCGGTGAGGAGTCGGTGAAGGGCGGTTACGACATGACCGCGTTCTGGTGCCGGGCCGGTACGGCCGCCACCATCACCCCG
CCGGGGATCGAGGGCATGATCGGCCCGCCCGGACCGGCGTACGGCGACACCATCTCCGGGACGAATCTGGCCGGCGGCAT
CGCGGCGGCGCTGTTCCGCAGGGAGCGCACCGGTGAGCCGTCGGTGGTCGACGTCTCGCTGCTGGGCAGCGGTCTGTGGG
CGATGGGCCACACCGTTGCGCTGACCTCGCACCTGAACCAGCTGATGGTGCAGCCGCCTCCTGGGGTGCACGGTTCGCCG
ATCAACCCGCTGGTGGGGGTGTACCCGACCGCCGACGACCGCTACATCTCGTTCGTGATGATGCAGCCGACGAAGTTCTG
GGCCGACGTGTGCAAGCACATGGATCTCGACGAGTACGCCGACGATCCGCGCTTCGCGTCCGCGGAGTCCTTCGCCGAGC
ACACCCCGGCCGCCGTCGAGATCCTCACCGAGGCAATGCGTAAGCGTCCACTGCCGGAGTGGAGTGAGCGGTTCGCGACG
CTGGCCGGTCCGTGGGCGCCCGTGCAGGACACACTGCAGGCGGCCAAGGACTCGCAGATCCGGGCCAACGAGTACATCGT
GCAGGCCGGCGAACTGGAACTGGTGGCCAACCCGGTCCAGTTCGACGTCGCCGCTCCACAGACCGCCGCCGCGCCCGGGT
TCGCCGAACAGACCGACGACATCCTCGTCGAACTCGGCCTCGACTGGGACCGCATCATCGAGCTCAAGACGGCCGGCGCC
GTCACGTGA

Upstream 100 bases:

>100_bases
CGCGAGATGGGCACCGCAGGCCTCGAGGAGTTCCTCGAATCCAAGACATTCGCGACGGTGGTGGGCTGATGAGCGCTTGC
GCGAAGAGGAGAGTGCGTTG

Downstream 100 bases:

>100_bases
CCCCGGAGATCTGAATGCCGTTCACATCTTCGGTCGGAACGACTCCGTCGGCCGAGCAGGCGTTTGAGACGGCAGGTCTT
GTTTCTGGAGATATCCATGT

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSRPLEGIRVLEVAMYGFVPSCGAVLGEWGAEVIKVEHAVTGDPQRGLRQTGPLRVEGDPNPNIEHANRGKRSIGLDMSV
PEGREVLLELARRADVFLTSFLPGHRQKFGIDVDDIRAVNPNIVYARGSALGPRGEESVKGGYDMTAFWCRAGTAATITP
PGIEGMIGPPGPAYGDTISGTNLAGGIAAALFRRERTGEPSVVDVSLLGSGLWAMGHTVALTSHLNQLMVQPPPGVHGSP
INPLVGVYPTADDRYISFVMMQPTKFWADVCKHMDLDEYADDPRFASAESFAEHTPAAVEILTEAMRKRPLPEWSERFAT
LAGPWAPVQDTLQAAKDSQIRANEYIVQAGELELVANPVQFDVAAPQTAAAPGFAEQTDDILVELGLDWDRIIELKTAGA
VT

Sequences:

>Translated_402_residues
MSRPLEGIRVLEVAMYGFVPSCGAVLGEWGAEVIKVEHAVTGDPQRGLRQTGPLRVEGDPNPNIEHANRGKRSIGLDMSV
PEGREVLLELARRADVFLTSFLPGHRQKFGIDVDDIRAVNPNIVYARGSALGPRGEESVKGGYDMTAFWCRAGTAATITP
PGIEGMIGPPGPAYGDTISGTNLAGGIAAALFRRERTGEPSVVDVSLLGSGLWAMGHTVALTSHLNQLMVQPPPGVHGSP
INPLVGVYPTADDRYISFVMMQPTKFWADVCKHMDLDEYADDPRFASAESFAEHTPAAVEILTEAMRKRPLPEWSERFAT
LAGPWAPVQDTLQAAKDSQIRANEYIVQAGELELVANPVQFDVAAPQTAAAPGFAEQTDDILVELGLDWDRIIELKTAGA
VT
>Mature_401_residues
SRPLEGIRVLEVAMYGFVPSCGAVLGEWGAEVIKVEHAVTGDPQRGLRQTGPLRVEGDPNPNIEHANRGKRSIGLDMSVP
EGREVLLELARRADVFLTSFLPGHRQKFGIDVDDIRAVNPNIVYARGSALGPRGEESVKGGYDMTAFWCRAGTAATITPP
GIEGMIGPPGPAYGDTISGTNLAGGIAAALFRRERTGEPSVVDVSLLGSGLWAMGHTVALTSHLNQLMVQPPPGVHGSPI
NPLVGVYPTADDRYISFVMMQPTKFWADVCKHMDLDEYADDPRFASAESFAEHTPAAVEILTEAMRKRPLPEWSERFATL
AGPWAPVQDTLQAAKDSQIRANEYIVQAGELELVANPVQFDVAAPQTAAAPGFAEQTDDILVELGLDWDRIIELKTAGAV
T

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate. Essential enzyme for the bacterium survival, as it relies on oxalic acid as its sole source of energy [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=413, Percent_Identity=27.6029055690073, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI300863124, Length=337, Percent_Identity=28.7833827893175, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI266456254, Length=413, Percent_Identity=25.181598062954, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI42794625, Length=402, Percent_Identity=24.6268656716418, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI300863126, Length=145, Percent_Identity=35.1724137931034, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI266458393, Length=276, Percent_Identity=26.8115942028986, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI266458397, Length=274, Percent_Identity=27.007299270073, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI266458395, Length=142, Percent_Identity=29.5774647887324, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI42822893, Length=142, Percent_Identity=29.5774647887324, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1788717, Length=437, Percent_Identity=27.6887871853547, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87082093, Length=367, Percent_Identity=24.7956403269755, Blast_Score=108, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI32564160, Length=289, Percent_Identity=26.2975778546713, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115535051, Length=334, Percent_Identity=24.8502994011976, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648431, Length=404, Percent_Identity=27.7227722772277, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24585488, Length=347, Percent_Identity=25.3602305475504, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 43239; Mature: 43108

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPLEGIRVLEVAMYGFVPSCGAVLGEWGAEVIKVEHAVTGDPQRGLRQTGPLRVEGDP
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHCHHEEEEEHHCCCCHHHHHHCCCCEEEECCC
NPNIEHANRGKRSIGLDMSVPEGREVLLELARRADVFLTSFLPGHRQKFGIDVDDIRAVN
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHEECC
PNIVYARGSALGPRGEESVKGGYDMTAFWCRAGTAATITPPGIEGMIGPPGPAYGDTISG
CCEEEECCCCCCCCCCHHCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCC
TNLAGGIAAALFRRERTGEPSVVDVSLLGSGLWAMGHTVALTSHLNQLMVQPPPGVHGSP
CCHHHHHHHHHHHHHCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCCCC
INPLVGVYPTADDRYISFVMMQPTKFWADVCKHMDLDEYADDPRFASAESFAEHTPAAVE
CCCCEEECCCCCCCEEEEEEECCHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHCCCHHHH
ILTEAMRKRPLPEWSERFATLAGPWAPVQDTLQAAKDSQIRANEYIVQAGELELVANPVQ
HHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEECCCEEEEECCEE
FDVAAPQTAAAPGFAEQTDDILVELGLDWDRIIELKTAGAVT
EECCCCCHHCCCCCCCCCCCEEEEECCCHHHEEEEECCCCCC
>Mature Secondary Structure 
SRPLEGIRVLEVAMYGFVPSCGAVLGEWGAEVIKVEHAVTGDPQRGLRQTGPLRVEGDP
CCCHHHHHHHHHHHHHCCCHHHHHHHHHCHHEEEEEHHCCCCHHHHHHCCCCEEEECCC
NPNIEHANRGKRSIGLDMSVPEGREVLLELARRADVFLTSFLPGHRQKFGIDVDDIRAVN
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHEECC
PNIVYARGSALGPRGEESVKGGYDMTAFWCRAGTAATITPPGIEGMIGPPGPAYGDTISG
CCEEEECCCCCCCCCCHHCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCC
TNLAGGIAAALFRRERTGEPSVVDVSLLGSGLWAMGHTVALTSHLNQLMVQPPPGVHGSP
CCHHHHHHHHHHHHHCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCCCC
INPLVGVYPTADDRYISFVMMQPTKFWADVCKHMDLDEYADDPRFASAESFAEHTPAAVE
CCCCEEECCCCCCCEEEEEEECCHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHCCCHHHH
ILTEAMRKRPLPEWSERFATLAGPWAPVQDTLQAAKDSQIRANEYIVQAGELELVANPVQ
HHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEECCCEEEEECCEE
FDVAAPQTAAAPGFAEQTDDILVELGLDWDRIIELKTAGAVT
EECCCCCHHCCCCCCCCCCCEEEEECCCHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9150242; 2361939 [H]