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The map label for this gene is cysW [H]

Identifier: 108800446

GI number: 108800446

Start: 3708116

End: 3708937

Strand: Reverse

Name: cysW [H]

Synonym: Mmcs_3480

Alternate gene names: 108800446

Gene position: 3708937-3708116 (Counterclockwise)

Preceding gene: 108800447

Following gene: 108800445

Centisome position: 65.01

GC content: 66.91

Gene sequence:

>822_bases
ATGCTGTTGTCGCCGGTGACGCGCCGGGTACTGCGCTTCGTCGCGCTGGCCTACATCCTGGTGCTGGTCGTCGTGCCGGT
GGGGCTGATCCTGTGGCGGACCTTCTCACCCGGCATCGGCGCGTTCGTCGCATCGATCGGGACCCCCGCGGCCATCAGCG
CGCTGCAGTTGTCGCTGCTCGTCGTGGCGATCGTCGTCCCGCTCAACGTGCTGTTCGGGGTTCCGACCGCGCTGGTGTTG
GCGCGCAACAAGTTCCGCGGTAAGAGCGCGCTCCAGGCGGTGATCGACCTGCCGTTCGCGGTGTCGCCGGTGGTCGTGGG
TGTCGCGCTGATCCTGCTGTGGGGGTCGGCCGGGGTGTTCGGATTCGTCGAGAACAACCTCGGCTTCAAGATCATCTTCG
GGCTGCCCGGCATCGTGCTCGCGAGCATCTTCGTCACCGTGCCGTTCGTCATCCGCGAGGTCGAACCGGTGCTGCACGAG
ATCGGCACCGACCAGGAGGAAGCCGCCTCGACCCTGGGCTCGCAGTGGTGGCAGACCTTCTGGCGGATCACGCTGCCGTC
GATCCGCTGGGGTCTCACGTATGGCGTGGTCCTCACCATCGCCCGCACACTGGGGGAGTACGGCGCGGTCATCATGGTGT
CGTCGAACCTGCCGGGCACCTCGCAGACCCTGACGCTGCTGGTGTCCGACCGTTACAACCGGGGTGCCGAATACGGTGCC
TACGCCGTGTCGACACTGCTCATGGGGGTCGCGGTGATCGTCCTGGTGGTCCAGGTGGTACTCGACGCCCGTCGGGGCCG
ACAGGAGAGCAGAGGGTCATGA

Upstream 100 bases:

>100_bases
TCGATCGTGCTGCTGGCGATCTCGTTCGTCGTGCTGTTGATCCTGCGCGCGCTCGGCGCGCGGGCGGCCAAACGGGAACA
GATGGCGGGGTGATCGAGCA

Downstream 100 bases:

>100_bases
CAGACGCGATCATCGTGCGCGGCGCCAACAAGCACTACGGCGACTTCGCGGCGCTGGACAACATCGACTTCGAGGTTCCG
GCCGGTTCGCTCACCGCACT

Product: Sulfate ABC transporter permease CysW

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MLLSPVTRRVLRFVALAYILVLVVVPVGLILWRTFSPGIGAFVASIGTPAAISALQLSLLVVAIVVPLNVLFGVPTALVL
ARNKFRGKSALQAVIDLPFAVSPVVVGVALILLWGSAGVFGFVENNLGFKIIFGLPGIVLASIFVTVPFVIREVEPVLHE
IGTDQEEAASTLGSQWWQTFWRITLPSIRWGLTYGVVLTIARTLGEYGAVIMVSSNLPGTSQTLTLLVSDRYNRGAEYGA
YAVSTLLMGVAVIVLVVQVVLDARRGRQESRGS

Sequences:

>Translated_273_residues
MLLSPVTRRVLRFVALAYILVLVVVPVGLILWRTFSPGIGAFVASIGTPAAISALQLSLLVVAIVVPLNVLFGVPTALVL
ARNKFRGKSALQAVIDLPFAVSPVVVGVALILLWGSAGVFGFVENNLGFKIIFGLPGIVLASIFVTVPFVIREVEPVLHE
IGTDQEEAASTLGSQWWQTFWRITLPSIRWGLTYGVVLTIARTLGEYGAVIMVSSNLPGTSQTLTLLVSDRYNRGAEYGA
YAVSTLLMGVAVIVLVVQVVLDARRGRQESRGS
>Mature_273_residues
MLLSPVTRRVLRFVALAYILVLVVVPVGLILWRTFSPGIGAFVASIGTPAAISALQLSLLVVAIVVPLNVLFGVPTALVL
ARNKFRGKSALQAVIDLPFAVSPVVVGVALILLWGSAGVFGFVENNLGFKIIFGLPGIVLASIFVTVPFVIREVEPVLHE
IGTDQEEAASTLGSQWWQTFWRITLPSIRWGLTYGVVLTIARTLGEYGAVIMVSSNLPGTSQTLTLLVSDRYNRGAEYGA
YAVSTLLMGVAVIVLVVQVVLDARRGRQESRGS

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=255, Percent_Identity=40, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1788764, Length=223, Percent_Identity=33.6322869955157, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1786980, Length=220, Percent_Identity=34.5454545454545, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29225; Mature: 29225

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSPVTRRVLRFVALAYILVLVVVPVGLILWRTFSPGIGAFVASIGTPAAISALQLSLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHH
VVAIVVPLNVLFGVPTALVLARNKFRGKSALQAVIDLPFAVSPVVVGVALILLWGSAGVF
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEE
GFVENNLGFKIIFGLPGIVLASIFVTVPFVIREVEPVLHEIGTDQEEAASTLGSQWWQTF
EEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
WRITLPSIRWGLTYGVVLTIARTLGEYGAVIMVSSNLPGTSQTLTLLVSDRYNRGAEYGA
HHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHEEEEECCCCCCCHHHH
YAVSTLLMGVAVIVLVVQVVLDARRGRQESRGS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLLSPVTRRVLRFVALAYILVLVVVPVGLILWRTFSPGIGAFVASIGTPAAISALQLSLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHH
VVAIVVPLNVLFGVPTALVLARNKFRGKSALQAVIDLPFAVSPVVVGVALILLWGSAGVF
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEE
GFVENNLGFKIIFGLPGIVLASIFVTVPFVIREVEPVLHEIGTDQEEAASTLGSQWWQTF
EEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
WRITLPSIRWGLTYGVVLTIARTLGEYGAVIMVSSNLPGTSQTLTLLVSDRYNRGAEYGA
HHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHEEEEECCCCCCCHHHH
YAVSTLLMGVAVIVLVVQVVLDARRGRQESRGS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1708375 [H]