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The map label for this gene is tldD [C]

Identifier: 108800395

GI number: 108800395

Start: 3638850

End: 3640367

Strand: Reverse

Name: tldD [C]

Synonym: Mmcs_3429

Alternate gene names: 108800395

Gene position: 3640367-3638850 (Counterclockwise)

Preceding gene: 108800396

Following gene: 108800394

Centisome position: 63.81

GC content: 69.57

Gene sequence:

>1518_bases
GTGACAGCGCCCCGACGTGTTGACGCCGACTTCCTCGCCCTGCCACGACAGCACCTGGCCGACGCCGCATTGTCGGCTGC
GCTGGCGGCGGGGGCGACCTACGCCGACCTGAGGATCCACGCGATCACCAGCGAACTGGTTCAGTTGCGCGACGGCGAAC
TCGAGACCGCGGTCATCGACCGGGAGATCGGCCTGGCCGTGCGGGTGATCGTCGACGGCACATGGGGGTTCGCCTCGCAC
GCCGAACTCGACCCGGCGGTGGCCGCCGACACCGCGCGGCGGGCGGTGGCCGTGGCGACGACGCTTGCCCCGCTCAACGC
CGAACGCATCGAACTGGCACCCGAACCGGTGTACCGCGACGTCAGCTGGGTGTCGGACTACCGCGTCGACCCGTTCATCG
TGCCCGCCGCGGACAAGATTGCCGTATTGGGTGAGTACTCCGGTCGGCTGCTCGCCGCGGACGGCGTCGACCACGTGTCG
GCCGGTCTGCACACCGCCAAGGAGCAGACGTTCTACGCCGACACGTTCGGGTCGTCGATCACCCAGCAGCGGGTGCGGGT
GCTGCCGACCCTCGATGCCGTCGCCGTCGACAGCGCCGCAGGGACATTCGAGACCATGCGCACCCTCGCCCCGCCGACCG
CGCGCGGCTGGGAGGTCGTCGCCGGCGACGAGGTGTGGGACTGGACCGCCGAACTCGCCGAGTTGCCGTCGCTGCTCGCG
GAGAAGGTCAAGGCGCCCGGCGTCACCGCCGGACCGACCGATCTGGTGATCGACCCGACGAACCTCTGGCTGACCATCCA
CGAATCCATCGGCCACGCCACCGAATACGACCGGGCCATCGGCTACGAGGCCGCCTACGCCGGCACGTCGTTCGCCACCC
CCGACAAACTCGGCACCATGCGGTACGGCTCACCGGTGATGAACGTGACCGCCGACCGGACCGTCGAATACGGCCTAGCG
TCAATCGGTTTCGACGACGAAGGCGTCCGCGCGCAGAGTTGGGACCTGGTGCGCGACGGGATCTTCGTCGGCTATCAGCT
CGACCGGGTCTTCGCCCCGCGGCTGGGGGTGGCCCGGTCCAACGGGTGCGCCTACGCCGACTCGCCGCACCACGTGCCGA
TCCAGCGGATGGCCAACGTGTCCCTGCAGCCGGCCGCCGAGGACGTCGGCACCGACGACCTGATCGCCCGCGTCGAGGAC
GGCCTGTACATCGTCGGCGACAAGAGCTGGTCGATCGACATGCAGCGCTACAACTTCCAGTTCACCGGTCAGCGGTTCTT
CCGGATCCGTGACGGCCGCCTCGACGGTCAGGTGCGTGACGTGGCGTATCAGGCGACGACGACGGACTTCTGGGGTGCGC
TCGAGGCCGTCGGCGGGCCGTCGACGTGGCGGCTCGGCGGGGCGTTCAACTGCGGTAAGGCCCAACCCGGACAGGTCGCG
GCGGTGAGCCACGGTTGTCCGTCGGCGCTGTTCCGGGGGATCAACGTGCTCAACACCCGTGAGGAGGCCGGTAGGTGA

Upstream 100 bases:

>100_bases
GTGTGCGGGGCGGCGCTGGCCGTGGAACTGACCGTGCTGCCGACGAGTTCGGCGCCCACCTGATCGGTGCCGTCGCCGCA
GCGCCACTACGGTGGATGCC

Downstream 100 bases:

>100_bases
TCGGGCCGCAGGACGTCGTCGACGCCGTACTCGCCGAAGCGGCCCGCCGGGGTCGCGCCGACGAGACGATCGTGCTGGTG
ACCGACCGGGCCGACGCGTC

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MTAPRRVDADFLALPRQHLADAALSAALAAGATYADLRIHAITSELVQLRDGELETAVIDREIGLAVRVIVDGTWGFASH
AELDPAVAADTARRAVAVATTLAPLNAERIELAPEPVYRDVSWVSDYRVDPFIVPAADKIAVLGEYSGRLLAADGVDHVS
AGLHTAKEQTFYADTFGSSITQQRVRVLPTLDAVAVDSAAGTFETMRTLAPPTARGWEVVAGDEVWDWTAELAELPSLLA
EKVKAPGVTAGPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGTMRYGSPVMNVTADRTVEYGLA
SIGFDDEGVRAQSWDLVRDGIFVGYQLDRVFAPRLGVARSNGCAYADSPHHVPIQRMANVSLQPAAEDVGTDDLIARVED
GLYIVGDKSWSIDMQRYNFQFTGQRFFRIRDGRLDGQVRDVAYQATTTDFWGALEAVGGPSTWRLGGAFNCGKAQPGQVA
AVSHGCPSALFRGINVLNTREEAGR

Sequences:

>Translated_505_residues
MTAPRRVDADFLALPRQHLADAALSAALAAGATYADLRIHAITSELVQLRDGELETAVIDREIGLAVRVIVDGTWGFASH
AELDPAVAADTARRAVAVATTLAPLNAERIELAPEPVYRDVSWVSDYRVDPFIVPAADKIAVLGEYSGRLLAADGVDHVS
AGLHTAKEQTFYADTFGSSITQQRVRVLPTLDAVAVDSAAGTFETMRTLAPPTARGWEVVAGDEVWDWTAELAELPSLLA
EKVKAPGVTAGPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGTMRYGSPVMNVTADRTVEYGLA
SIGFDDEGVRAQSWDLVRDGIFVGYQLDRVFAPRLGVARSNGCAYADSPHHVPIQRMANVSLQPAAEDVGTDDLIARVED
GLYIVGDKSWSIDMQRYNFQFTGQRFFRIRDGRLDGQVRDVAYQATTTDFWGALEAVGGPSTWRLGGAFNCGKAQPGQVA
AVSHGCPSALFRGINVLNTREEAGR
>Mature_504_residues
TAPRRVDADFLALPRQHLADAALSAALAAGATYADLRIHAITSELVQLRDGELETAVIDREIGLAVRVIVDGTWGFASHA
ELDPAVAADTARRAVAVATTLAPLNAERIELAPEPVYRDVSWVSDYRVDPFIVPAADKIAVLGEYSGRLLAADGVDHVSA
GLHTAKEQTFYADTFGSSITQQRVRVLPTLDAVAVDSAAGTFETMRTLAPPTARGWEVVAGDEVWDWTAELAELPSLLAE
KVKAPGVTAGPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGTMRYGSPVMNVTADRTVEYGLAS
IGFDDEGVRAQSWDLVRDGIFVGYQLDRVFAPRLGVARSNGCAYADSPHHVPIQRMANVSLQPAAEDVGTDDLIARVEDG
LYIVGDKSWSIDMQRYNFQFTGQRFFRIRDGRLDGQVRDVAYQATTTDFWGALEAVGGPSTWRLGGAFNCGKAQPGQVAA
VSHGCPSALFRGINVLNTREEAGR

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=262, Percent_Identity=24.8091603053435, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 54375; Mature: 54244

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPRRVDADFLALPRQHLADAALSAALAAGATYADLRIHAITSELVQLRDGELETAVID
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCEEHEEEEEHHHHHHHHHCCCCEEEEEEE
REIGLAVRVIVDGTWGFASHAELDPAVAADTARRAVAVATTLAPLNAERIELAPEPVYRD
CCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHEEEEEEECCCCCCCCEECCCCCHHHC
VSWVSDYRVDPFIVPAADKIAVLGEYSGRLLAADGVDHVSAGLHTAKEQTFYADTFGSSI
HHHHHCCCCCCEEECCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHCCEEEEHHHCCHH
TQQRVRVLPTLDAVAVDSAAGTFETMRTLAPPTARGWEVVAGDEVWDWTAELAELPSLLA
HHHHHHHCCCCHHHEECCCCCHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHH
EKVKAPGVTAGPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGTM
HHHCCCCCCCCCCCEEECCCCEEEEEEHHCCCHHHHHHHCCCHHHCCCCCCCCCCCCCCE
RYGSPVMNVTADRTVEYGLASIGFDDEGVRAQSWDLVRDGIFVGYQLDRVFAPRLGVARS
ECCCCCEEEECCCHHHHCCEECCCCCCCCCCCCCHHHHCCEEEEEEECHHHCCCCCCCCC
NGCAYADSPHHVPIQRMANVSLQPAAEDVGTDDLIARVEDGLYIVGDKSWSIDMQRYNFQ
CCEEECCCCCCCCHHHHHCCCCCCCHHHCCCHHHHHHHCCCEEEEECCCEEEEEEEEEEE
FTGQRFFRIRDGRLDGQVRDVAYQATTTDFWGALEAVGGPSTWRLGGAFNCGKAQPGQVA
ECCCEEEEEECCCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCEE
AVSHGCPSALFRGINVLNTREEAGR
EECCCCHHHHHHCCHHCCCHHHHCC
>Mature Secondary Structure 
TAPRRVDADFLALPRQHLADAALSAALAAGATYADLRIHAITSELVQLRDGELETAVID
CCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCEEHEEEEEHHHHHHHHHCCCCEEEEEEE
REIGLAVRVIVDGTWGFASHAELDPAVAADTARRAVAVATTLAPLNAERIELAPEPVYRD
CCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHEEEEEEECCCCCCCCEECCCCCHHHC
VSWVSDYRVDPFIVPAADKIAVLGEYSGRLLAADGVDHVSAGLHTAKEQTFYADTFGSSI
HHHHHCCCCCCEEECCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHCCEEEEHHHCCHH
TQQRVRVLPTLDAVAVDSAAGTFETMRTLAPPTARGWEVVAGDEVWDWTAELAELPSLLA
HHHHHHHCCCCHHHEECCCCCHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHH
EKVKAPGVTAGPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGTM
HHHCCCCCCCCCCCEEECCCCEEEEEEHHCCCHHHHHHHCCCHHHCCCCCCCCCCCCCCE
RYGSPVMNVTADRTVEYGLASIGFDDEGVRAQSWDLVRDGIFVGYQLDRVFAPRLGVARS
ECCCCCEEEECCCHHHHCCEECCCCCCCCCCCCCHHHHCCEEEEEEECHHHCCCCCCCCC
NGCAYADSPHHVPIQRMANVSLQPAAEDVGTDDLIARVEDGLYIVGDKSWSIDMQRYNFQ
CCEEECCCCCCCCHHHHHCCCCCCCHHHCCCHHHHHHHCCCEEEEECCCEEEEEEEEEEE
FTGQRFFRIRDGRLDGQVRDVAYQATTTDFWGALEAVGGPSTWRLGGAFNCGKAQPGQVA
ECCCEEEEEECCCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCEE
AVSHGCPSALFRGINVLNTREEAGR
EECCCCHHHHHHCCHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]