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The map label for this gene is fabH [H]

Identifier: 108800380

GI number: 108800380

Start: 3623920

End: 3625032

Strand: Reverse

Name: fabH [H]

Synonym: Mmcs_3414

Alternate gene names: 108800380

Gene position: 3625032-3623920 (Counterclockwise)

Preceding gene: 108800381

Following gene: 108800379

Centisome position: 63.54

GC content: 68.19

Gene sequence:

>1113_bases
GTGACGCTGGTGAGCACTCATTGGCTGGTGATGGACCACTCGAGGGACGGTGACGGCGCGCCGTACCGCACCCGGTTGGC
CGCGGCCGGCCGGCATCTGCCCGCGACCCGTCTGACGACCGACGAGTTGATGTCGTCGACGCGGCACAACACCCACATCG
ACCTCGAACGCCTCACCGGGATCCACGAGCGCCGGGTGTCGGTCGGGGACGAGGACTCCTACAGCCTGGCCACCACGGCG
GCGCGCGACTGCCTGGACAGGGCTGAGACGCCGGCCTCCGAGATCGACGTCGTCATCAGCTGCAGCATCACGAAGTTCCA
CGGCGGTCTGACCCAGTGGATGGAACCGACGATGAGCAGCGCGGTCGCGCATGCCATCGGTGCACAGCGGGCGATGACGT
TCGACCTGTCCAATGCGTGCGCCGGGATGCTCACGGGCGTCACGGTTCTGAACAACTGGATACGCCAGGGCGTGGTGCGG
CGGGGCCTGGTGGTCAGCGGCGAATACATCTCCCAGCTGGGCCACAATGCCGCCCGCCACATCCGCACCATCATGAGCAA
GGAACTGGCCTGTCTGACCCTGGGCGACGCCGGCGCTGCATTGCTGCTCGAACGCGCCGGCGCCGACTCGGGCGCGATCA
GCCTGGCCGGCTTCACCACGATCGCCGACCACAGCCGGCTGTGCCTGGCCTACCCGAAGGGCCGCGATCCGGGGGCGCGG
ATGTTCACCGACTCCCGGGCGATCCAGCGGGCGGCGATCGCCGACACGCCGGTGCTGCTGCACGAGGTCCTGGACGCGGC
CGGGATCGCGATCCACGACATCGACCACGTGATCACGCATCAGACCTCGGCGCGGGCCATCCGCAAGGGGATGGCCGAGA
TGTCCGCGGTCTTCGGCGACAGCCCCCGCCACGACGCGGTGATCACCGTCGACCGCTACGGGAACACGGCGTCGACGACA
CATACGGTGGCCCTCGTCGAAGAGTTGGAGGCAGGCCACATCGAGCCCGGCGAGACGATCGCGCTCATCGCGCTGGCGTC
GGGGCTCGAGATCGGGGTCGTACTCATCGAGGTGGACGAGGATCTGGTGAATCGCTATGGGCACCATCATTGA

Upstream 100 bases:

>100_bases
GCCGTGCTGGCCGAGATCGAGCACATGCCGTCAGGCCGCCAACAAGGGTCCAAATGCCCTGGCCGCGGGTCGCCGCGGTG
AACCACGATCACATCGGGAG

Downstream 100 bases:

>100_bases
TCGGGTCGAGCTGACGCGCGGCGGCTGGCGCACCCGGCACAGTGCCCTGCACCTCGCGGTCGCGGCCGCCAGATCGTGTC
TCGACGCCGCGCAGCGGGAT

Product: 3-oxoacyl-(acyl-carrier protein) synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTLVSTHWLVMDHSRDGDGAPYRTRLAAAGRHLPATRLTTDELMSSTRHNTHIDLERLTGIHERRVSVGDEDSYSLATTA
ARDCLDRAETPASEIDVVISCSITKFHGGLTQWMEPTMSSAVAHAIGAQRAMTFDLSNACAGMLTGVTVLNNWIRQGVVR
RGLVVSGEYISQLGHNAARHIRTIMSKELACLTLGDAGAALLLERAGADSGAISLAGFTTIADHSRLCLAYPKGRDPGAR
MFTDSRAIQRAAIADTPVLLHEVLDAAGIAIHDIDHVITHQTSARAIRKGMAEMSAVFGDSPRHDAVITVDRYGNTASTT
HTVALVEELEAGHIEPGETIALIALASGLEIGVVLIEVDEDLVNRYGHHH

Sequences:

>Translated_370_residues
MTLVSTHWLVMDHSRDGDGAPYRTRLAAAGRHLPATRLTTDELMSSTRHNTHIDLERLTGIHERRVSVGDEDSYSLATTA
ARDCLDRAETPASEIDVVISCSITKFHGGLTQWMEPTMSSAVAHAIGAQRAMTFDLSNACAGMLTGVTVLNNWIRQGVVR
RGLVVSGEYISQLGHNAARHIRTIMSKELACLTLGDAGAALLLERAGADSGAISLAGFTTIADHSRLCLAYPKGRDPGAR
MFTDSRAIQRAAIADTPVLLHEVLDAAGIAIHDIDHVITHQTSARAIRKGMAEMSAVFGDSPRHDAVITVDRYGNTASTT
HTVALVEELEAGHIEPGETIALIALASGLEIGVVLIEVDEDLVNRYGHHH
>Mature_369_residues
TLVSTHWLVMDHSRDGDGAPYRTRLAAAGRHLPATRLTTDELMSSTRHNTHIDLERLTGIHERRVSVGDEDSYSLATTAA
RDCLDRAETPASEIDVVISCSITKFHGGLTQWMEPTMSSAVAHAIGAQRAMTFDLSNACAGMLTGVTVLNNWIRQGVVRR
GLVVSGEYISQLGHNAARHIRTIMSKELACLTLGDAGAALLLERAGADSGAISLAGFTTIADHSRLCLAYPKGRDPGARM
FTDSRAIQRAAIADTPVLLHEVLDAAGIAIHDIDHVITHQTSARAIRKGMAEMSAVFGDSPRHDAVITVDRYGNTASTTH
TVALVEELEAGHIEPGETIALIALASGLEIGVVLIEVDEDLVNRYGHHH

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=336, Percent_Identity=22.6190476190476, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 39721; Mature: 39590

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVSTHWLVMDHSRDGDGAPYRTRLAAAGRHLPATRLTTDELMSSTRHNTHIDLERLTG
CCEEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEHHHHCC
IHERRVSVGDEDSYSLATTAARDCLDRAETPASEIDVVISCSITKFHGGLTQWMEPTMSS
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEEEEEEHHHCCCHHHHHHHHHHH
AVAHAIGAQRAMTFDLSNACAGMLTGVTVLNNWIRQGVVRRGLVVSGEYISQLGHNAARH
HHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHH
IRTIMSKELACLTLGDAGAALLLERAGADSGAISLAGFTTIADHSRLCLAYPKGRDPGAR
HHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCEEEECCCEECCCCCEEEECCCCCCCCCC
MFTDSRAIQRAAIADTPVLLHEVLDAAGIAIHDIDHVITHQTSARAIRKGMAEMSAVFGD
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
SPRHDAVITVDRYGNTASTTHTVALVEELEAGHIEPGETIALIALASGLEIGVVLIEVDE
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEEEEECH
DLVNRYGHHH
HHHHHCCCCC
>Mature Secondary Structure 
TLVSTHWLVMDHSRDGDGAPYRTRLAAAGRHLPATRLTTDELMSSTRHNTHIDLERLTG
CEEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEHHHHCC
IHERRVSVGDEDSYSLATTAARDCLDRAETPASEIDVVISCSITKFHGGLTQWMEPTMSS
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEEEEEEHHHCCCHHHHHHHHHHH
AVAHAIGAQRAMTFDLSNACAGMLTGVTVLNNWIRQGVVRRGLVVSGEYISQLGHNAARH
HHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHH
IRTIMSKELACLTLGDAGAALLLERAGADSGAISLAGFTTIADHSRLCLAYPKGRDPGAR
HHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCEEEECCCEECCCCCEEEECCCCCCCCCC
MFTDSRAIQRAAIADTPVLLHEVLDAAGIAIHDIDHVITHQTSARAIRKGMAEMSAVFGD
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
SPRHDAVITVDRYGNTASTTHTVALVEELEAGHIEPGETIALIALASGLEIGVVLIEVDE
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEEEEECH
DLVNRYGHHH
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA