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The map label for this gene is trxB [H]

Identifier: 108800306

GI number: 108800306

Start: 3540464

End: 3541402

Strand: Reverse

Name: trxB [H]

Synonym: Mmcs_3340

Alternate gene names: 108800306

Gene position: 3541402-3540464 (Counterclockwise)

Preceding gene: 108800308

Following gene: 108800305

Centisome position: 62.07

GC content: 71.78

Gene sequence:

>939_bases
ATGGACGACATCTGGGATTGCGTGATCATCGGCGGCGGCGCCGCCGGACTGAGCGCCGCGCTGGTACTGGGGCGGGCGCG
CCGCCGCACACTCGTGGTGGATGCCGGTGAGCCGAGTAATGCGGTGGCGCACGGGATCGGCGGGCTGCTCGGACACGACG
GGCGGGCGCCGGCGGAGCTGTACGCCGCCGGGCGAGCGGAGCTGACGAGATACCCGCAGGTGCAACTGCGCACCGGAGTG
GTGACCGACGTGCGGCGGGGCGAGCAGTTCACCGTCGAACTGGCCGACGGCACAGTCGAACTCGCGCGACGCATCGTGCT
CGCGACCGGTATGCAGTACCGCCTGCAGGAAGTTCCCGGCCTGGCGCAGATGTGGGGCGATGCGGTGTTCCACTGCCCGT
TCTGTCACGGCTGGGAGGTGCGTGACGCCCCGGTCGCGGTGCTGGCCGACGGCGCCCGGGCGGTGCACGCCGGACTGCTC
CTGCGCGGGTGGAGTGACGACATCGTGGTGCTCGCAGGAGATGTCGGCGACGACCGCGTGCTGCTGGAGGCCGCGGGCAT
CCTGATCGAAGGACGGCCGGTCACCGAGGTGCGCGCGGCCGGAGAGGGTCTCGAGGTCGTCTTCGCCGACGGTTCGGTAC
TGGGCCGGCGGGCGCTGATGGTCGCGGCGTCGGTGGGTCAGCGGTCCGCGCTGGCCGAACGGCTCGGCGTGCGGTTCGGT
GAGCCGAATCCCCTTTCGGCCGAGGCGGTCTGGGTCGACGAGTTCGGCCGCACGTCGGTGCCCGGGGTGTTCGCCGCCGG
TGACGTCACCGTGGCGCTGCCGCAGGTGGCCGCGGCGATCGCGGCCGGTTCGAAGGTGGCCGCGGCGGTCATGCAGAGCC
TGCTGGCCGACGAGTTCGGATTGCCGGTACCGGCATGGAAGGAGGACGTGAATGTCTGA

Upstream 100 bases:

>100_bases
CGCTTGCGTACCCGTTGGTCCACGCTGTCCTCGGACGCCTCGTTTGCCTGCATGGCAAATAAGCTTGCCACCTGTAGCGG
CTACACGGCAACCTCGGGAC

Downstream 100 bases:

>100_bases
GACGGTGGAGTTCTGGGAGGAGCACTACGGCGCGAAGGACCGGGTGTGGAGCGGCCGGGTCAATGTTCGGCTGGCCGAGA
TCGTCGAACCGTTGCCGCCG

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MDDIWDCVIIGGGAAGLSAALVLGRARRRTLVVDAGEPSNAVAHGIGGLLGHDGRAPAELYAAGRAELTRYPQVQLRTGV
VTDVRRGEQFTVELADGTVELARRIVLATGMQYRLQEVPGLAQMWGDAVFHCPFCHGWEVRDAPVAVLADGARAVHAGLL
LRGWSDDIVVLAGDVGDDRVLLEAAGILIEGRPVTEVRAAGEGLEVVFADGSVLGRRALMVAASVGQRSALAERLGVRFG
EPNPLSAEAVWVDEFGRTSVPGVFAAGDVTVALPQVAAAIAAGSKVAAAVMQSLLADEFGLPVPAWKEDVNV

Sequences:

>Translated_312_residues
MDDIWDCVIIGGGAAGLSAALVLGRARRRTLVVDAGEPSNAVAHGIGGLLGHDGRAPAELYAAGRAELTRYPQVQLRTGV
VTDVRRGEQFTVELADGTVELARRIVLATGMQYRLQEVPGLAQMWGDAVFHCPFCHGWEVRDAPVAVLADGARAVHAGLL
LRGWSDDIVVLAGDVGDDRVLLEAAGILIEGRPVTEVRAAGEGLEVVFADGSVLGRRALMVAASVGQRSALAERLGVRFG
EPNPLSAEAVWVDEFGRTSVPGVFAAGDVTVALPQVAAAIAAGSKVAAAVMQSLLADEFGLPVPAWKEDVNV
>Mature_312_residues
MDDIWDCVIIGGGAAGLSAALVLGRARRRTLVVDAGEPSNAVAHGIGGLLGHDGRAPAELYAAGRAELTRYPQVQLRTGV
VTDVRRGEQFTVELADGTVELARRIVLATGMQYRLQEVPGLAQMWGDAVFHCPFCHGWEVRDAPVAVLADGARAVHAGLL
LRGWSDDIVVLAGDVGDDRVLLEAAGILIEGRPVTEVRAAGEGLEVVFADGSVLGRRALMVAASVGQRSALAERLGVRFG
EPNPLSAEAVWVDEFGRTSVPGVFAAGDVTVALPQVAAAIAAGSKVAAAVMQSLLADEFGLPVPAWKEDVNV

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 32535; Mature: 32535

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDIWDCVIIGGGAAGLSAALVLGRARRRTLVVDAGEPSNAVAHGIGGLLGHDGRAPAEL
CCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHH
YAAGRAELTRYPQVQLRTGVVTDVRRGEQFTVELADGTVELARRIVLATGMQYRLQEVPG
HHCCCHHHHCCCCEEEECCCHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHCCC
LAQMWGDAVFHCPFCHGWEVRDAPVAVLADGARAVHAGLLLRGWSDDIVVLAGDVGDDRV
HHHHHCCCEEECCCCCCCCCCCCCEEEEECCCHHHHHHEEEECCCCCEEEEECCCCCCEE
LLEAAGILIEGRPVTEVRAAGEGLEVVFADGSVLGRRALMVAASVGQRSALAERLGVRFG
EEEECCEEEECCCCHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCC
EPNPLSAEAVWVDEFGRTSVPGVFAAGDVTVALPQVAAAIAAGSKVAAAVMQSLLADEFG
CCCCCCCEEEEEECCCCCCCCCEEECCCEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCC
LPVPAWKEDVNV
CCCCCCHHCCCC
>Mature Secondary Structure
MDDIWDCVIIGGGAAGLSAALVLGRARRRTLVVDAGEPSNAVAHGIGGLLGHDGRAPAEL
CCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHH
YAAGRAELTRYPQVQLRTGVVTDVRRGEQFTVELADGTVELARRIVLATGMQYRLQEVPG
HHCCCHHHHCCCCEEEECCCHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHCCC
LAQMWGDAVFHCPFCHGWEVRDAPVAVLADGARAVHAGLLLRGWSDDIVVLAGDVGDDRV
HHHHHCCCEEECCCCCCCCCCCCCEEEEECCCHHHHHHEEEECCCCCEEEEECCCCCCEE
LLEAAGILIEGRPVTEVRAAGEGLEVVFADGSVLGRRALMVAASVGQRSALAERLGVRFG
EEEECCEEEECCCCHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCC
EPNPLSAEAVWVDEFGRTSVPGVFAAGDVTVALPQVAAAIAAGSKVAAAVMQSLLADEFG
CCCCCCCEEEEEECCCCCCCCCEEECCCEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCC
LPVPAWKEDVNV
CCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]