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The map label for this gene is paaG [H]

Identifier: 108800299

GI number: 108800299

Start: 3534492

End: 3535271

Strand: Reverse

Name: paaG [H]

Synonym: Mmcs_3333

Alternate gene names: 108800299

Gene position: 3535271-3534492 (Counterclockwise)

Preceding gene: 108800305

Following gene: 108800297

Centisome position: 61.96

GC content: 70.0

Gene sequence:

>780_bases
GTGAGCGAATACGAGGCAATCACCTTCGAGCAGTCAGGTCCGGTGGCCCGGATCGTGTTGAACCGCCCGGAGGCGGCGAA
CGGGATGAACGACACCATGACCGCCGAACTCGCCGACGCCGCCGCGCGCTGCGACACCTCGGCGACCAAGGCGGTGGTGC
TCACCGGGTCCGGCCGCTTCTTCTGTGCCGGAGGCGATCTCAAGGCTTTCGCGACGGCGCCGTCGCGGGGCCGGTTCATC
AAGGGCGTCGCCGACGATCTGCACCGGGCCGTCTCGACATTCGCCCGGATGGACGCCGTGCTGGTGACCGCGGTCAACGG
CGCCGCGGCCGGGGCCGGTTTCAGCATCGCCGTGGCCGGCGACCTGGTACTGGCCGCCGAATCCGCGTCGTTCACGATGG
CCTACACCAAGGTCGGGCTGAGCCCGGACGGCAGCGCCTCGTACCACCTGCCGCGACTGATCGGGATGCGCCGCGCGCAG
GAGCTCATGCTGACCAACCGCACACTGTCGGCCGGCGAAGCCCTCGACTGGGGTCTGGTCACCGACGTGGTACCCGACGC
CGAACTCGGCGACCGCGCGACCGCGCTGGCCGATCAGTTGGCCGGCGGTTCGGCGCCGTCGCACGGTGCGGTCAAGACGC
TGCTGCTGGCCTCGCTGAAGAACGGTCTCGAAGAGCAGATGGAACTCGAGGGCCGGACGATTGCGCGCCGCGCCGACTCC
GCCGACGGCCGCGAAGGTGTCGACGCGTTCCTCGCCAAACGCAGGGCGGACTTCGCGTAA

Upstream 100 bases:

>100_bases
GTCTTGGCTGCCATGTCCACCTTCGCTGGTCCGTGGGGGCCACAAGCCTGCCACACCGAGGTGAACGAGCCCCGACGACG
GCGATCGCTACAGTCCCCCT

Downstream 100 bases:

>100_bases
GACAGTCCGCCTAGAAGCTGTGCTCCTCGGCCGGGAACACCCCGGCCGCCACCTCGTCGGCGTACTGGCTTGCCGCACGG
CGCAATTCGGCGCCGACATC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSEYEAITFEQSGPVARIVLNRPEAANGMNDTMTAELADAAARCDTSATKAVVLTGSGRFFCAGGDLKAFATAPSRGRFI
KGVADDLHRAVSTFARMDAVLVTAVNGAAAGAGFSIAVAGDLVLAAESASFTMAYTKVGLSPDGSASYHLPRLIGMRRAQ
ELMLTNRTLSAGEALDWGLVTDVVPDAELGDRATALADQLAGGSAPSHGAVKTLLLASLKNGLEEQMELEGRTIARRADS
ADGREGVDAFLAKRRADFA

Sequences:

>Translated_259_residues
MSEYEAITFEQSGPVARIVLNRPEAANGMNDTMTAELADAAARCDTSATKAVVLTGSGRFFCAGGDLKAFATAPSRGRFI
KGVADDLHRAVSTFARMDAVLVTAVNGAAAGAGFSIAVAGDLVLAAESASFTMAYTKVGLSPDGSASYHLPRLIGMRRAQ
ELMLTNRTLSAGEALDWGLVTDVVPDAELGDRATALADQLAGGSAPSHGAVKTLLLASLKNGLEEQMELEGRTIARRADS
ADGREGVDAFLAKRRADFA
>Mature_258_residues
SEYEAITFEQSGPVARIVLNRPEAANGMNDTMTAELADAAARCDTSATKAVVLTGSGRFFCAGGDLKAFATAPSRGRFIK
GVADDLHRAVSTFARMDAVLVTAVNGAAAGAGFSIAVAGDLVLAAESASFTMAYTKVGLSPDGSASYHLPRLIGMRRAQE
LMLTNRTLSAGEALDWGLVTDVVPDAELGDRATALADQLAGGSAPSHGAVKTLLLASLKNGLEEQMELEGRTIARRADSA
DGREGVDAFLAKRRADFA

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI25453481, Length=260, Percent_Identity=28.8461538461538, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI51538573, Length=260, Percent_Identity=28.8461538461538, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI4757968, Length=258, Percent_Identity=29.0697674418605, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI49355787, Length=258, Percent_Identity=29.0697674418605, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI45643119, Length=200, Percent_Identity=31, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI260275230, Length=200, Percent_Identity=31, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI260274832, Length=200, Percent_Identity=31, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4757966, Length=249, Percent_Identity=29.718875502008, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI51538581, Length=249, Percent_Identity=29.718875502008, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI194097323, Length=261, Percent_Identity=29.5019157088123, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI221136756, Length=234, Percent_Identity=29.4871794871795, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI221136753, Length=234, Percent_Identity=29.4871794871795, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI221307494, Length=234, Percent_Identity=29.4871794871795, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI116235487, Length=231, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI31542718, Length=263, Percent_Identity=28.1368821292776, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI70995211, Length=225, Percent_Identity=29.3333333333333, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI37594469, Length=217, Percent_Identity=27.6497695852535, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4502327, Length=247, Percent_Identity=27.9352226720648, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI37594471, Length=217, Percent_Identity=27.6497695852535, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787660, Length=254, Percent_Identity=41.7322834645669, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI221142681, Length=262, Percent_Identity=31.2977099236641, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787659, Length=250, Percent_Identity=33.6, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1788597, Length=267, Percent_Identity=31.0861423220974, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87082183, Length=261, Percent_Identity=25.2873563218391, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790281, Length=196, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788682, Length=108, Percent_Identity=35.1851851851852, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17535521, Length=261, Percent_Identity=29.1187739463602, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI25145438, Length=252, Percent_Identity=31.3492063492063, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17560910, Length=256, Percent_Identity=28.125, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17554946, Length=265, Percent_Identity=30.9433962264151, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17549921, Length=241, Percent_Identity=27.3858921161826, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17534483, Length=179, Percent_Identity=27.3743016759777, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540306, Length=254, Percent_Identity=26.3779527559055, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=169, Percent_Identity=27.810650887574, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25144157, Length=209, Percent_Identity=29.6650717703349, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25144160, Length=209, Percent_Identity=29.6650717703349, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=204, Percent_Identity=27.9411764705882, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129971, Length=261, Percent_Identity=30.6513409961686, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24653477, Length=261, Percent_Identity=30.6513409961686, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24654903, Length=187, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24653139, Length=254, Percent_Identity=28.3464566929134, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28571730, Length=183, Percent_Identity=29.5081967213115, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571729, Length=183, Percent_Identity=29.5081967213115, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920382, Length=256, Percent_Identity=27.734375, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21357171, Length=180, Percent_Identity=28.8888888888889, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19922422, Length=268, Percent_Identity=24.2537313432836, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 26869; Mature: 26737

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYEAITFEQSGPVARIVLNRPEAANGMNDTMTAELADAAARCDTSATKAVVLTGSGRF
CCCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCEE
FCAGGDLKAFATAPSRGRFIKGVADDLHRAVSTFARMDAVLVTAVNGAAAGAGFSIAVAG
EEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEC
DLVLAAESASFTMAYTKVGLSPDGSASYHLPRLIGMRRAQELMLTNRTLSAGEALDWGLV
CEEEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
TDVVPDAELGDRATALADQLAGGSAPSHGAVKTLLLASLKNGLEEQMELEGRTIARRADS
HHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
ADGREGVDAFLAKRRADFA
CCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SEYEAITFEQSGPVARIVLNRPEAANGMNDTMTAELADAAARCDTSATKAVVLTGSGRF
CCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCEE
FCAGGDLKAFATAPSRGRFIKGVADDLHRAVSTFARMDAVLVTAVNGAAAGAGFSIAVAG
EEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEC
DLVLAAESASFTMAYTKVGLSPDGSASYHLPRLIGMRRAQELMLTNRTLSAGEALDWGLV
CEEEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
TDVVPDAELGDRATALADQLAGGSAPSHGAVKTLLLASLKNGLEEQMELEGRTIARRADS
HHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
ADGREGVDAFLAKRRADFA
CCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]