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The map label for this gene is trpD [H]

Identifier: 108800256

GI number: 108800256

Start: 3487225

End: 3488298

Strand: Reverse

Name: trpD [H]

Synonym: Mmcs_3290

Alternate gene names: 108800256

Gene position: 3488298-3487225 (Counterclockwise)

Preceding gene: 108800261

Following gene: 108800254

Centisome position: 61.14

GC content: 70.76

Gene sequence:

>1074_bases
ATGGCGTGGGAACATCTGCGCGTGACTGATACTCCCACGTGGCCGTCGATCCTGGGGCGGTTGACCACCGGACAGAATCT
GGGGACCGGGCAGGCCGCCTGGGCGATGGACCAGATCATGACCGGGACGGCCACCCCGGCTCAGATCGCCGGGTTCGCGG
TGGCGATGAAACTCAAGCGCCCGACGTCGGCGGAGGTCACCGAACTCGCCGACGTGATGCTCAAGCACGCGCGCCGCATC
CCGACCGACATCATCGGAAACGAGACGGTCGACATCGTCGGCACCGGCGGCGACGGTGCAAACACCGTCAACCTCTCCAC
GATGGCGGCGATCGTGGTGGCCGCCGCGGGGGTGCCGGTGATGAAGCACGGCAACCGGGCCGCCTCGTCGCTGTCCGGCG
GGGCCGACACCCTCGAAGCGCTCGGCGTCCGGATCGACCTCGGTCCCGAACAGGTGGCGGCGTCCGTGGCCGAGGTCGGT
ATCGGATTCGCGTTCGCCAACCAGTTCCACCCGTCGTACAAGCACGCCTCGGCCGTGCGCCGGGAGCTCGGGGTGCCGAC
GGTGTTCAACCTGCTCGGACCGCTGACCAACCCCGCGCGTCCGCGCGCCGGGCTGATCGGCTGCGCGTGGGCGGAGCTGG
CCGAGGTGATGGCCGGGGTCTTCGCGTCGCGCAACTCCAGCGTGCTGGTGGTGCACGGCGACGACGGCCTCGACGAGCTG
ACCACGACCACCACGAGCACGATCTGGCGCGTGCAGGCGGGCACGGTCGAGAGGTTGACCTTCGACCCGGCGGCCTTCGG
CTTCCAGCGCGCGCACCTGTCCGAACTCGTCGGTGGCGACGCCGAGTACAACGCCGCCGAGGTGCGGGCGGTGCTCGGGG
GTGCAAAGGGCGCGGTGCGCGATGCGGTGGTGCTCAACGCCGCGGGCGCGCTGGTCGCACACGCCGGGCTATCCAGCGAC
GCCAAATGGGTGCCGGCCTGGGAGGCGGGCCTGGCCCGGGCGACCGAGACCATCGACTCCGGGGCGGCCGAAAAGCTGCT
CGCGCGTTGGGTGCGGTTCACCCAGAAGCTCTGA

Upstream 100 bases:

>100_bases
CGCAAGTATGACGCTTTGTAGTTGTCGAACTCCACCCGGGTCGCCTAATCGTCACAAGTGTCGTACGGGAAGATCGGGCG
GACCTTTGGGAAGTTCCCGG

Downstream 100 bases:

>100_bases
GGGGACCGACTCTCTGGTCCTCGCGTCCGCACCGGTCTGCTCGGCGGCCAACCGTGCCGAACGCGCCGTATCCGCCCAGC
CCAGCCAGCGGCCCGCCGCG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MAWEHLRVTDTPTWPSILGRLTTGQNLGTGQAAWAMDQIMTGTATPAQIAGFAVAMKLKRPTSAEVTELADVMLKHARRI
PTDIIGNETVDIVGTGGDGANTVNLSTMAAIVVAAAGVPVMKHGNRAASSLSGGADTLEALGVRIDLGPEQVAASVAEVG
IGFAFANQFHPSYKHASAVRRELGVPTVFNLLGPLTNPARPRAGLIGCAWAELAEVMAGVFASRNSSVLVVHGDDGLDEL
TTTTTSTIWRVQAGTVERLTFDPAAFGFQRAHLSELVGGDAEYNAAEVRAVLGGAKGAVRDAVVLNAAGALVAHAGLSSD
AKWVPAWEAGLARATETIDSGAAEKLLARWVRFTQKL

Sequences:

>Translated_357_residues
MAWEHLRVTDTPTWPSILGRLTTGQNLGTGQAAWAMDQIMTGTATPAQIAGFAVAMKLKRPTSAEVTELADVMLKHARRI
PTDIIGNETVDIVGTGGDGANTVNLSTMAAIVVAAAGVPVMKHGNRAASSLSGGADTLEALGVRIDLGPEQVAASVAEVG
IGFAFANQFHPSYKHASAVRRELGVPTVFNLLGPLTNPARPRAGLIGCAWAELAEVMAGVFASRNSSVLVVHGDDGLDEL
TTTTTSTIWRVQAGTVERLTFDPAAFGFQRAHLSELVGGDAEYNAAEVRAVLGGAKGAVRDAVVLNAAGALVAHAGLSSD
AKWVPAWEAGLARATETIDSGAAEKLLARWVRFTQKL
>Mature_356_residues
AWEHLRVTDTPTWPSILGRLTTGQNLGTGQAAWAMDQIMTGTATPAQIAGFAVAMKLKRPTSAEVTELADVMLKHARRIP
TDIIGNETVDIVGTGGDGANTVNLSTMAAIVVAAAGVPVMKHGNRAASSLSGGADTLEALGVRIDLGPEQVAASVAEVGI
GFAFANQFHPSYKHASAVRRELGVPTVFNLLGPLTNPARPRAGLIGCAWAELAEVMAGVFASRNSSVLVVHGDDGLDELT
TTTTSTIWRVQAGTVERLTFDPAAFGFQRAHLSELVGGDAEYNAAEVRAVLGGAKGAVRDAVVLNAAGALVAHAGLSSDA
KWVPAWEAGLARATETIDSGAAEKLLARWVRFTQKL

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=295, Percent_Identity=32.8813559322034, Blast_Score=156, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320561, Length=332, Percent_Identity=29.8192771084337, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 37119; Mature: 36987

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWEHLRVTDTPTWPSILGRLTTGQNLGTGQAAWAMDQIMTGTATPAQIAGFAVAMKLKR
CCCCCEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEEECC
PTSAEVTELADVMLKHARRIPTDIIGNETVDIVGTGGDGANTVNLSTMAAIVVAAAGVPV
CCCHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHCCCCH
MKHGNRAASSLSGGADTLEALGVRIDLGPEQVAASVAEVGIGFAFANQFHPSYKHASAVR
HHCCCHHHHHCCCCHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RELGVPTVFNLLGPLTNPARPRAGLIGCAWAELAEVMAGVFASRNSSVLVVHGDDGLDEL
HHCCCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHH
TTTTTSTIWRVQAGTVERLTFDPAAFGFQRAHLSELVGGDAEYNAAEVRAVLGGAKGAVR
HHHHHHEEEEEECCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHH
DAVVLNAAGALVAHAGLSSDAKWVPAWEAGLARATETIDSGAAEKLLARWVRFTQKL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AWEHLRVTDTPTWPSILGRLTTGQNLGTGQAAWAMDQIMTGTATPAQIAGFAVAMKLKR
CCCCEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEEECC
PTSAEVTELADVMLKHARRIPTDIIGNETVDIVGTGGDGANTVNLSTMAAIVVAAAGVPV
CCCHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHCCCCH
MKHGNRAASSLSGGADTLEALGVRIDLGPEQVAASVAEVGIGFAFANQFHPSYKHASAVR
HHCCCHHHHHCCCCHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RELGVPTVFNLLGPLTNPARPRAGLIGCAWAELAEVMAGVFASRNSSVLVVHGDDGLDEL
HHCCCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHH
TTTTTSTIWRVQAGTVERLTFDPAAFGFQRAHLSELVGGDAEYNAAEVRAVLGGAKGAVR
HHHHHHEEEEEECCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHH
DAVVLNAAGALVAHAGLSSDAKWVPAWEAGLARATETIDSGAAEKLLARWVRFTQKL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA