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The map label for this gene is 108800161

Identifier: 108800161

GI number: 108800161

Start: 3386602

End: 3388095

Strand: Reverse

Name: 108800161

Synonym: Mmcs_3195

Alternate gene names: NA

Gene position: 3388095-3386602 (Counterclockwise)

Preceding gene: 108800162

Following gene: 108800160

Centisome position: 59.38

GC content: 57.56

Gene sequence:

>1494_bases
ATGACAGGCACCACGACGACGTTGATCGTCGGCGCCGGGTTCGCAGGTATCGGTGCGGCGATCAGACTGCTTCAAGAGGG
CACGGATGACTTCGTCATCCTGGAACGGTCAGATCGCGTCGGAGGCACCTGGCGAGACAATACTTATCCCGGTGCGGCCT
GCGATATTCCCTCGCTTCTCTACTCCTACTCGTTCGAGCCGAATCCGGGCTGGACTCGTACCTACTCGGGGAGCGCTGAG
ATCCTCGAATATATCGACGATATGGTCGACAAGTACGATCTTGCCCGGTTCATCCAGTTTGATACCGACGTGACTGCCTT
GGAATTCGATGAGAGTGCCGGCATCTGGATGGCCGACACGGCAGATGGAAAGCGGTATCACACCCGGTCAGTTGTGATGG
CCAGTGGACCACTTGCCAACGCCAGCTTTCCCGATATTCGGGGTATTGACTCGTACGGTGGAAAAAAGATCCACAGCGCT
CGATGGGACCATGGCTACGATCTCGGCGGTAAGAGGGTTGCAGTCATCGGGACAGGCGCGAGCGCGGTTCAGATCATTCC
CGAGCTCGTAAAGTCGGCTGCCTCGGTCAAAGTCTTCCAGAGAACGCCCGGCTGGGTGTTGCCCAGGGTGAACTTCAGGC
ATCCGGCCTGGGCGCGTTCGACCTTCACACACCTGCCGGTGAGCGAACAAGCGCTCCGCGACGCGTGGTTTTGGGCCCAC
GAAGTGATGGCAGTGGGTATGGTCTGGAACACCGCCGCGACGTCCGCGATACAGCTGGCGGCCAAGGCTCATCTCCGTCG
GCAGGTGAAAGACTCCTGGTTGAGACGTCAGTTGACGCCCCATTTCAGGCCTGGATGCAAGCGCATGCTCATGACCAGTG
ATTATTACCCTGCGCTACAGGCGGATAACTGCAAGCTGATCAGCTGGCCGATCGCCACATTGTCACCCAACGGTGTTCGG
ACCGCCGACGGTGTCGAGCACGAAGTGGACTGTATCGTATTTGCCACTGGCTTCGATGTGGCCAAACGTGGCACCCCGTT
CCCGATTAGCGGCCTCGGCGGTCGGAAGCTCGGCGATGAATGGTCTCAGGGGACATTTGCCTTCAAGAGCGTGAGCGTGG
CCGGGTATCCGAACTTATTCTTCACTTTCGGACCGAATTCCGGGCCAGGCCACAACTCGGCGCTCGTATATATGGAGGCT
GCAATTGACTATATAGTCAAGGCGATCAAGCTCCTTCAGCAAAATGACATCGGCACTTTGGATGTGAGGGAGGATCGTCA
GGACCGCTATCACTCCGAAATTCAGCGCCGCCTTCGACGAACGACTTGGAATTCGGGGTGCAGCAGTTGGTATTTGACCG
AGGACGGCTACAACGGCACGATGTACCCAGGTTTCGCGACCCAGTTTATGAGAGAACTATCCCGCTTGGATCCTCATGAT
TACGTGATAACCCGGCGCGACGATACACACGTCGAGCTGACGCAATCACTCTGA

Upstream 100 bases:

>100_bases
TGTCTCAGCGCCTTGGCAATGCGATCGATGTTTTCCCTGTTCAGATTTTCGGTCGGCCGCCATCCTGGACGGACGAACTG
ACCTACGAACCGGTTGCCAA

Downstream 100 bases:

>100_bases
ATACAAGTTTGCAGGGCTGACCGTCAGAACGGTGAAATACAGGAATGGATCGCAAGTCCGACCGTAATTACGAGATAATT
ATCATAGGAGCTGGATTTTC

Product: putative monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 496

Protein sequence:

>497_residues
MTGTTTTLIVGAGFAGIGAAIRLLQEGTDDFVILERSDRVGGTWRDNTYPGAACDIPSLLYSYSFEPNPGWTRTYSGSAE
ILEYIDDMVDKYDLARFIQFDTDVTALEFDESAGIWMADTADGKRYHTRSVVMASGPLANASFPDIRGIDSYGGKKIHSA
RWDHGYDLGGKRVAVIGTGASAVQIIPELVKSAASVKVFQRTPGWVLPRVNFRHPAWARSTFTHLPVSEQALRDAWFWAH
EVMAVGMVWNTAATSAIQLAAKAHLRRQVKDSWLRRQLTPHFRPGCKRMLMTSDYYPALQADNCKLISWPIATLSPNGVR
TADGVEHEVDCIVFATGFDVAKRGTPFPISGLGGRKLGDEWSQGTFAFKSVSVAGYPNLFFTFGPNSGPGHNSALVYMEA
AIDYIVKAIKLLQQNDIGTLDVREDRQDRYHSEIQRRLRRTTWNSGCSSWYLTEDGYNGTMYPGFATQFMRELSRLDPHD
YVITRRDDTHVELTQSL

Sequences:

>Translated_497_residues
MTGTTTTLIVGAGFAGIGAAIRLLQEGTDDFVILERSDRVGGTWRDNTYPGAACDIPSLLYSYSFEPNPGWTRTYSGSAE
ILEYIDDMVDKYDLARFIQFDTDVTALEFDESAGIWMADTADGKRYHTRSVVMASGPLANASFPDIRGIDSYGGKKIHSA
RWDHGYDLGGKRVAVIGTGASAVQIIPELVKSAASVKVFQRTPGWVLPRVNFRHPAWARSTFTHLPVSEQALRDAWFWAH
EVMAVGMVWNTAATSAIQLAAKAHLRRQVKDSWLRRQLTPHFRPGCKRMLMTSDYYPALQADNCKLISWPIATLSPNGVR
TADGVEHEVDCIVFATGFDVAKRGTPFPISGLGGRKLGDEWSQGTFAFKSVSVAGYPNLFFTFGPNSGPGHNSALVYMEA
AIDYIVKAIKLLQQNDIGTLDVREDRQDRYHSEIQRRLRRTTWNSGCSSWYLTEDGYNGTMYPGFATQFMRELSRLDPHD
YVITRRDDTHVELTQSL
>Mature_496_residues
TGTTTTLIVGAGFAGIGAAIRLLQEGTDDFVILERSDRVGGTWRDNTYPGAACDIPSLLYSYSFEPNPGWTRTYSGSAEI
LEYIDDMVDKYDLARFIQFDTDVTALEFDESAGIWMADTADGKRYHTRSVVMASGPLANASFPDIRGIDSYGGKKIHSAR
WDHGYDLGGKRVAVIGTGASAVQIIPELVKSAASVKVFQRTPGWVLPRVNFRHPAWARSTFTHLPVSEQALRDAWFWAHE
VMAVGMVWNTAATSAIQLAAKAHLRRQVKDSWLRRQLTPHFRPGCKRMLMTSDYYPALQADNCKLISWPIATLSPNGVRT
ADGVEHEVDCIVFATGFDVAKRGTPFPISGLGGRKLGDEWSQGTFAFKSVSVAGYPNLFFTFGPNSGPGHNSALVYMEAA
IDYIVKAIKLLQQNDIGTLDVREDRQDRYHSEIQRRLRRTTWNSGCSSWYLTEDGYNGTMYPGFATQFMRELSRLDPHDY
VITRRDDTHVELTQSL

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503757, Length=360, Percent_Identity=26.3888888888889, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4503755, Length=356, Percent_Identity=26.685393258427, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI50541965, Length=222, Percent_Identity=30.1801801801802, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI50541961, Length=222, Percent_Identity=30.1801801801802, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI221316678, Length=251, Percent_Identity=27.4900398406374, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4503759, Length=218, Percent_Identity=26.605504587156, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI221316674, Length=251, Percent_Identity=27.4900398406374, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI221316672, Length=251, Percent_Identity=27.4900398406374, Blast_Score=76, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25145785, Length=214, Percent_Identity=25.7009345794392, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 55355; Mature: 55224

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTTTTLIVGAGFAGIGAAIRLLQEGTDDFVILERSDRVGGTWRDNTYPGAACDIPSLL
CCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
YSYSFEPNPGWTRTYSGSAEILEYIDDMVDKYDLARFIQFDTDVTALEFDESAGIWMADT
HHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEC
ADGKRYHTRSVVMASGPLANASFPDIRGIDSYGGKKIHSARWDHGYDLGGKRVAVIGTGA
CCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCC
SAVQIIPELVKSAASVKVFQRTPGWVLPRVNFRHPAWARSTFTHLPVSEQALRDAWFWAH
HHHHHHHHHHHHHHHEEEEECCCCEEECCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHH
EVMAVGMVWNTAATSAIQLAAKAHLRRQVKDSWLRRQLTPHFRPGCKRMLMTSDYYPALQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEECCCCCCCC
ADNCKLISWPIATLSPNGVRTADGVEHEVDCIVFATGFDVAKRGTPFPISGLGGRKLGDE
CCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCHHHCCCCCCCCCCCCCCCCCC
WSQGTFAFKSVSVAGYPNLFFTFGPNSGPGHNSALVYMEAAIDYIVKAIKLLQQNDIGTL
CCCCEEEEEEEEECCCCCEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCEE
DVREDRQDRYHSEIQRRLRRTTWNSGCSSWYLTEDGYNGTMYPGFATQFMRELSRLDPHD
ECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCC
YVITRRDDTHVELTQSL
EEEEECCCCCEEEECCC
>Mature Secondary Structure 
TGTTTTLIVGAGFAGIGAAIRLLQEGTDDFVILERSDRVGGTWRDNTYPGAACDIPSLL
CCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
YSYSFEPNPGWTRTYSGSAEILEYIDDMVDKYDLARFIQFDTDVTALEFDESAGIWMADT
HHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEC
ADGKRYHTRSVVMASGPLANASFPDIRGIDSYGGKKIHSARWDHGYDLGGKRVAVIGTGA
CCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCC
SAVQIIPELVKSAASVKVFQRTPGWVLPRVNFRHPAWARSTFTHLPVSEQALRDAWFWAH
HHHHHHHHHHHHHHHEEEEECCCCEEECCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHH
EVMAVGMVWNTAATSAIQLAAKAHLRRQVKDSWLRRQLTPHFRPGCKRMLMTSDYYPALQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEECCCCCCCC
ADNCKLISWPIATLSPNGVRTADGVEHEVDCIVFATGFDVAKRGTPFPISGLGGRKLGDE
CCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCHHHCCCCCCCCCCCCCCCCCC
WSQGTFAFKSVSVAGYPNLFFTFGPNSGPGHNSALVYMEAAIDYIVKAIKLLQQNDIGTL
CCCCEEEEEEEEECCCCCEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCEE
DVREDRQDRYHSEIQRRLRRTTWNSGCSSWYLTEDGYNGTMYPGFATQFMRELSRLDPHD
ECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCC
YVITRRDDTHVELTQSL
EEEEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]