Click here to switch to the map view.

The map label for this gene is yfbT [C]

Identifier: 108800114

GI number: 108800114

Start: 3337722

End: 3338408

Strand: Reverse

Name: yfbT [C]

Synonym: Mmcs_3148

Alternate gene names: 108800114

Gene position: 3338408-3337722 (Counterclockwise)

Preceding gene: 108800115

Following gene: 108800113

Centisome position: 58.51

GC content: 69.0

Gene sequence:

>687_bases
ATGAGAGCGGTGCTGTGGGACATGGATGGAACGCTCGTCGACTCCGAAAAGCTCTGGGACGTCTCGCTTGCCGCGCTCTA
CGACCGGCTCGGCGGGGTGATCACCGACGAGTTGCGCACCGCCCTGGTCGGCAGTTCCGCGGAGAACACCATCAAGACGA
TCTTCGCCGACCTCGGCCTCGAACCCGACCCCGCGGCGATGGCCGAGGCCGACAGATGGCTGCACGATCACACCGGCGAC
CTGTTCGCCACCCACGGTCTGCCGTGGTGCGACGGCGCCCGCGAACTGCTGGAAGCCCTTGCGGGCGAAGGTGTTCCGAT
GGCATTGGTCACCAACACCCAGCGCGCGCTGACCGAGCAGGCGCTCGACAGCATCGGCCGCCACTTCTTCTCGGTGACCG
TCTGTGGTGACGAGGTGCCCAACGGCAAACCCGAACCGGACCCCTACCGCCGCGCCGCCGCACTGCTCGACCTCGACCCC
GGTCACTGCTTGGCGGTGGAGGATTCGGTCACCGGCACTCTCGCCGCCGAACTCGCCGGGTGCCCGGTCCTCGTGGTCCC
CAACGACGTCGTCGTCCCACCGAGCCCGCGCCGCAGGCACGTCGACTCGCTGCGCGACGTGGCCGTCGACGACCTGCGCG
CATTCCACGCCGAGATCGCCGCCGCCTCCGGTAAACGCAGCGCCTGA

Upstream 100 bases:

>100_bases
ACCCGGAGGACTGAACGTTGATCGTCGCGAATGTGACGTTGTGCGCGAGAATTCGGCAGAAACCCAAACACGAGCTCACG
TTCGGCGGGGGACTGCGCGC

Downstream 100 bases:

>100_bases
CAGCCGATATCCGGCGCCGCCCGGTTTCGCTCAGCGCACTTGCGGGAACCCGCCTTTTCCGGCCGGATCGGTGTTTGAAT
GTGATTCCGGTCACGCGACG

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MRAVLWDMDGTLVDSEKLWDVSLAALYDRLGGVITDELRTALVGSSAENTIKTIFADLGLEPDPAAMAEADRWLHDHTGD
LFATHGLPWCDGARELLEALAGEGVPMALVTNTQRALTEQALDSIGRHFFSVTVCGDEVPNGKPEPDPYRRAAALLDLDP
GHCLAVEDSVTGTLAAELAGCPVLVVPNDVVVPPSPRRRHVDSLRDVAVDDLRAFHAEIAAASGKRSA

Sequences:

>Translated_228_residues
MRAVLWDMDGTLVDSEKLWDVSLAALYDRLGGVITDELRTALVGSSAENTIKTIFADLGLEPDPAAMAEADRWLHDHTGD
LFATHGLPWCDGARELLEALAGEGVPMALVTNTQRALTEQALDSIGRHFFSVTVCGDEVPNGKPEPDPYRRAAALLDLDP
GHCLAVEDSVTGTLAAELAGCPVLVVPNDVVVPPSPRRRHVDSLRDVAVDDLRAFHAEIAAASGKRSA
>Mature_228_residues
MRAVLWDMDGTLVDSEKLWDVSLAALYDRLGGVITDELRTALVGSSAENTIKTIFADLGLEPDPAAMAEADRWLHDHTGD
LFATHGLPWCDGARELLEALAGEGVPMALVTNTQRALTEQALDSIGRHFFSVTVCGDEVPNGKPEPDPYRRAAALLDLDP
GHCLAVEDSVTGTLAAELAGCPVLVVPNDVVVPPSPRRRHVDSLRDVAVDDLRAFHAEIAAASGKRSA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=191, Percent_Identity=29.8429319371728, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI87082080, Length=207, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789787, Length=200, Percent_Identity=31, Blast_Score=63, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116008157, Length=192, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20129151, Length=196, Percent_Identity=30.6122448979592, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17137324, Length=192, Percent_Identity=31.25, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR000150
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24367; Mature: 24367

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVLWDMDGTLVDSEKLWDVSLAALYDRLGGVITDELRTALVGSSAENTIKTIFADLGL
CCEEEECCCCCEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCC
EPDPAAMAEADRWLHDHTGDLFATHGLPWCDGARELLEALAGEGVPMALVTNTQRALTEQ
CCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHH
ALDSIGRHFFSVTVCGDEVPNGKPEPDPYRRAAALLDLDPGHCLAVEDSVTGTLAAELAG
HHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHHHEECCCCCEEEECCCCCHHHHHHHCC
CPVLVVPNDVVVPPSPRRRHVDSLRDVAVDDLRAFHAEIAAASGKRSA
CCEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRAVLWDMDGTLVDSEKLWDVSLAALYDRLGGVITDELRTALVGSSAENTIKTIFADLGL
CCEEEECCCCCEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCC
EPDPAAMAEADRWLHDHTGDLFATHGLPWCDGARELLEALAGEGVPMALVTNTQRALTEQ
CCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHH
ALDSIGRHFFSVTVCGDEVPNGKPEPDPYRRAAALLDLDPGHCLAVEDSVTGTLAAELAG
HHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHHHEECCCCCEEEECCCCCHHHHHHHCC
CPVLVVPNDVVVPPSPRRRHVDSLRDVAVDDLRAFHAEIAAASGKRSA
CCEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA